Genome Editing & T-Cells

Genome editing technologies enable the editing of genes to create or correct mutations or express genes of interest. Here is the latest research on genome editing in T- cells and their application in human diseases such as adoptive T-cell immunotherapy for cancer.

January 23, 2021

Chimeric Antigen Receptor T-cell Therapy for Melanoma.

Expert Review of Clinical Immunology
Azadehsadat RazaviNima Rezaei
January 26, 2021
Review

Bacterial exopolysaccharides: Chemical structures, gene clusters and genetic engineering.

International Journal of Biological Macromolecules
Xiaqing Sun, Jianfa Zhang
January 23, 2021

Preclinical Chimeric Antibody Chimeric Antigen Receptor T Cell Progress in Digestive System Cancers.

Cancer Biotherapy & Radiopharmaceuticals
Peng LüKeping Chen
January 22, 2021
Open Access

CRISPR-Cas9 gene editing of hepatitis B virus in chronically infected humanized mice.

Molecular Therapy. Methods & Clinical Development
Daniel StoneKeith R Jerome
January 21, 2021

Mitochondrial replacement therapy: Genetic counselors' experiences, knowledge, and opinions.

Journal of Genetic Counseling
Anjali AryamvallyJulianne E Hartmann
January 21, 2021
Review

Clinical development of natural killer cells expressing chimeric antigen receptors.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
Ryan J Golden, Andrew D Fesnak
January 23, 2021
Open Access

The Roles of the miRNAome and Transcriptome in the Ovine Ovary Reveal Poor Efficiency in Juvenile Superovulation.

Animals : an Open Access Journal From MDPI
Xiaosheng ZhangXiaofei Guo
January 21, 2021
Review
Open Access

Origin, Regulation, and Fitness Effect of Chromosomal Rearrangements in the Yeast Saccharomyces cerevisiae.

International Journal of Molecular Sciences
Xing-Xing TangDao-Qiong Zheng
January 26, 2021
Review

Cardiomyocyte Death and Genome-Edited Stem Cell Therapy for Ischemic Heart Disease.

Stem Cell Reviews and Reports
Hyun-Min Cho, Je-Yoel Cho
January 24, 2021
Open Access

ADO/hypotaurine: a novel metabolic pathway contributing to glioblastoma development.

Cell Death Discovery
Dachuan ShenRuoyu Wang
January 24, 2021

Correction of a Urea Cycle Defect after ex vivo Gene Editing of Human Hepatocytes.

Molecular Therapy : the Journal of the American Society of Gene Therapy
Mihaela ZabulicaStephen C Strom
January 24, 2021

Anti-CD117 immunotherapy to eliminate hematopoietic and leukemia stem cells.

Experimental Hematology
Norman F RusskampMarkus G Manz
January 26, 2021

Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes.

Circulation Research
Jonas PeperStephan E Lehnart
January 26, 2021
Open Access

Optimization of CRISPR/Cas System for Improving Genome Editing Efficiency in Plasmodium falciparum.

Frontiers in Microbiology
Yuemeng ZhaoQingfeng Zhang
January 26, 2021
Open Access

Abscisic acid-mediated induction of FLAVIN-CONTAINING MONOOXYGENASE 2 leads to reduced accumulation of methylthioalkyl glucosinolates in Arabidopsis thaliana.

Plant Science : an International Journal of Experimental Plant Biology
Yimeng LiMasami Yokota Hirai

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