Feed Preview

Fast Growing

Genome Surgery & Neuronal Disorders

Genome Surgery & Neuronal Disorders diagram by

Genome surgery using CRISPR genomic techniques offer the potential to correct disease-causing mutations in many neuronal disorders. Here are the latest discoveries pertaining to genome surgery and neuronal disorders.

Top 20 most recent papers
bioRxiv

Gene replacement therapy provides benefit in an adult mouse model of Leigh syndrome

bioRxivJanuary 9, 2020
Robin Reynaud-DulaurierMichael Decressac
6
Journal of Neurology

Expert consensus recommendations to improve diagnosis of ATTR amyloidosis with polyneuropathy

Journal of NeurologyJanuary 8, 2020
David AdamsGiampaolo Merlini
33
1
Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry

Discovery of Selective SIRT2 Inhibitors as Therapeutic Agents in B-Cell Lymphoma and Other Malignancies

Molecules : a Journal of Synthetic Chemistry and Natural Product ChemistryJanuary 25, 2020
Sarwat ChowdhuryJulian A Simon
Antioxidants & Redox Signaling

NADPH oxidase and neurodegenerative diseases: mechanisms and therapy

Antioxidants & Redox SignalingJanuary 24, 2020
Liyan HouQingshan Wang
Molecular Neurobiology

CRISPR, Prime Editing, Optogenetics, and DREADDs: New Therapeutic Approaches Provided by Emerging Technologies in the Treatment of Spinal Cord Injury

Molecular NeurobiologyJanuary 14, 2020
Vera PaschonAlexandre Hiroaki Kihara
1
PloS One

Astrocyte senescence promotes glutamate toxicity in cortical neurons

PloS OneJanuary 17, 2020
Chandani LimbadJudith Campisi
1
1
Cell Death & Disease

Interferon mediated neuroinflammation in polyglutamine disease is not caused by RNA toxicity

Cell Death & DiseaseJanuary 11, 2020
Aksheev BhambriBeena Pillai
1
1
Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Clinical potential and current progress of mesenchymal stem cells for Parkinson's disease: a systematic review

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical NeurophysiologyJanuary 11, 2020
Ying ChenXiaosu Gu
2
1
Neurologia i neurochirurgia polska

Spinal muscular atrophy - new therapies, new challenges

Neurologia i neurochirurgia polskaJanuary 11, 2020
Maria Jędrzejowska, Anna Kostera-Pruszczyk
Tissue Engineering and Regenerative Medicine

Combination of Human Mesenchymal Stem Cells and Repetitive Transcranial Magnetic Stimulation Enhances Neurological Recovery of 6-Hydroxydopamine Model of Parkinsonian's Disease

Tissue Engineering and Regenerative MedicineJanuary 24, 2020
Ji Yong LeeByung Pil Cho
2
International Journal of Molecular Sciences

Progress of Induced Pluripotent Stem Cell Technologies to Understand Genetic Epilepsy

International Journal of Molecular SciencesJanuary 17, 2020
Bruno SterliniAnna Corradi
1
European Journal of Medicinal Chemistry

A review of currently identified small molecule modulators of microRNA function

European Journal of Medicinal ChemistryJanuary 14, 2020
Emile N Van MeterKelly A Teske
2
Journal of Clinical Medicine

Glial Cells-The Strategic Targets in Amyotrophic Lateral Sclerosis Treatment

Journal of Clinical MedicineJanuary 23, 2020
Tereza FilipiAnd Miroslava Anderova
1
JCI Insight

Gigaxonin glycosylation regulates intermediate filament turnover and may impact giant axonal neuropathy etiology or treatment

JCI InsightJanuary 17, 2020
Po-Han ChenMichael Boyce
9
CNS Drugs

Recent Advances in the Treatment of Huntington's Disease: Targeting DNA and RNA

CNS DrugsJanuary 15, 2020
Kathleen M Shannon
3
1
Drug Delivery and Translational Research

Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B

Drug Delivery and Translational ResearchJanuary 17, 2020
Anita GroverAnil Bagri
Cardiology in Review

Catecholaminergic Polymorphic Ventricular Tachycardia

Cardiology in ReviewJanuary 15, 2020
Chan W KimWilliam H Frishman
1
Molecular Therapy. Methods & Clinical Development

7T MRI Predicts Amelioration of Neurodegeneration in the Brain after AAV Gene Therapy

Molecular Therapy. Methods & Clinical DevelopmentJanuary 24, 2020
Heather L Gray-EdwardsDouglas R Martin
2
Molecular Therapy. Methods & Clinical Development

Intralingual and Intrapleural AAV Gene Therapy Prolongs Survival in a SOD1 ALS Mouse Model

Molecular Therapy. Methods & Clinical DevelopmentJanuary 24, 2020
Allison M KeelerMai K ElMallah
European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society

Genetic potassium channel-associated epilepsies: Clinical review of the Kv family

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology SocietyJanuary 15, 2020
Nicholas M AllenHolger Lerche

See more papers from this feed

Related Feeds

ALS

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

ALS & FTD: TDP-43

ALS shares with a considerable proportion of FTD cases the same neuropathological substrate, namely, inclusions of abnormally phosphorylated protein tdp-43 (ptdp-43). Here are the latest discoveries pertaining to ptdp-43 and these diseases.

ALS - Pathogenic Mechanisms

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating pathogenic mechanisms that underlie this genetically heterogeneous disorder.

ALS - Phenotypes

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating phenotypes associated with this genetically heterogeneous disorder.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here are the latest discoveries pertaining to this disease.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research.

ALS: Therapies

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS therapies here.

ALS: Transposon de-silencing

Transposon silencing is a form of transcriptional gene silencing. These gene silencing mechanisms are impaired in Amyotrophic lateral sclerosis (ALS). Here are the latest discoveries pertaining to transposon silencing and this disease.

Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

© 2020 Meta ULC. All rights reserved
/feed-previews/genome-surgery-neuronal-disorders/46af9a03-6bab-45f4-a4c4-2f46679f9852