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Genome Surgery & Neuronal Disorders

Genome Surgery & Neuronal Disorders diagram by undefined

Genome surgery using CRISPR genomic techniques offer the potential to correct disease-causing mutations in many neuronal disorders. Here are the latest discoveries pertaining to genome surgery and neuronal disorders.

Top 20 most recent papers
bioRxiv

Protein thermal stability does not correlate with cellular half-life: Global observations and a case study of tripeptidyl-peptidase 1

bioRxivNovember 11, 2019
Aaron Michael CollierPeter Lobel
4
Scientific Reports

The Effect of Early Rounds of ex vivo Expansion and Cryopreservation on the Adipogenic Differentiation Capacity of Adipose-Derived Stromal/Stem Cells

Scientific ReportsNovember 4, 2019
Chrisna DurandtMichael Sean Pepper
Scientific Reports

Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice

Scientific ReportsNovember 20, 2019
Jerel Adam FieldsNigel A Calcutt
2
Cellular and Molecular Life Sciences : CMLS

A role of cellular translation regulation associated with toxic Huntingtin protein

Cellular and Molecular Life Sciences : CMLSDecember 3, 2019
Hiranmay JoagAmitabha Majumdar
Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology

Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation

Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune PharmacologyDecember 4, 2019
Marina V AksenovaMichael S Shtutman
Journal of Neurology

Do heterozygous mutations of Niemann-Pick type C predispose to late-onset neurodegeneration: a review of the literature

Journal of NeurologyNovember 7, 2019
Susanne Annika SchneiderTatiana Bremova-Ertl
2
2
Cell Reports

TDP-43 Regulates Coupled Dendritic mRNA Transport-Translation Processes in Co-operation with FMRP and Staufen1

Cell ReportsDecember 3, 2019
Jen-Fei ChuChe-Kun James Shen
International Journal of Molecular Sciences

B Vitamins and Fatty Acids: What Do They Share with Small Vessel Disease-Related Dementia?

International Journal of Molecular SciencesNovember 18, 2019
rita moretti, Costanza Peinkhofer
4
1
Natural Product Reports

Targeting and extending the eukaryotic druggable genome with natural products: cytoskeletal targets of natural products

Natural Product ReportsNovember 25, 2019
April L Risinger, Lin Du
Annals of Neurology

Early Intrathecal T Helper 17.1 Cell Activity in Huntington Disease

Annals of NeurologyNovember 14, 2019
Marina Rode von EssenFinn Thorup Sellebjerg
4
2
NPJ Genomic Medicine

Identification and targeted management of a neurodegenerative disorder caused by biallelic mutations in SLC5A6

NPJ Genomic MedicineNovember 14, 2019
Alicia B ByrneHamish Steele Scott
9
Frontiers in Pharmacology

Recent Advances in the Use of Focused Ultrasound for Magnetic Resonance Image-Guided Therapeutic Nanoparticle Delivery to the Central Nervous System

Frontiers in PharmacologyNovember 13, 2019
Delaney G Fisher, Richard J Price
Diagnostics

Systematic Approach for Drug Repositioning of Anti-Epileptic Drugs

DiagnosticsNovember 30, 2019
Youn-Hee KoJin-Sung Lee
International Journal of Molecular Sciences

Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases

International Journal of Molecular SciencesNovember 30, 2019
Julia KonovalovaAndrii Domanskyi
AIDS

Symptomatic cerebrospinal fluid escape

AIDSDecember 1, 2019
Andrea MastrangeloPaola Cinque
Theranostics

Strategy to enhance transgene expression in proximity of amyloid plaques in a mouse model of Alzheimer's disease

TheranosticsOctober 18, 2019
Danielle Weber-AdrianIsabelle Aubert
2
1
Frontiers in Genetics

Diagnostic Yield of a Targeted Next-Generation Sequencing Gene Panel for Pediatric-Onset Movement Disorders: A 3-Year Cohort Study

Frontiers in GeneticsOctober 29, 2019
Federica GraziolaAlessandro Capuano
Journal of Ethnopharmacology

Tibetan medicine Ru-yi-Zhen-bao Pills exhibits anti-migraine effect through mediating PAG anti-nociceptive channel

Journal of EthnopharmacologyNovember 30, 2019
Ya Min LuoXiao Hua Tao
JIMD Reports

High diagnostic yield of direct Sanger sequencing in the diagnosis of neuronal ceroid lipofuscinoses

JIMD ReportsNovember 1, 2019
Abdulhakim JilaniSaadet Mercimek-Mahmutoglu
Molecular Therapy. Methods & Clinical Development

AAV5-miHTT Lowers Huntingtin mRNA and Protein without Off-Target Effects in Patient-Derived Neuronal Cultures and Astrocytes

Molecular Therapy. Methods & Clinical DevelopmentNovember 19, 2019
Sonay KeskinMelvin M Evers
4
1
4

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