Genomic Instability & Aging

During aging, it has been shown that genomic instability increases. This leads to mutations, cellular dysfunction, mitochondrial DNA damage, which may increase the risk for neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease and ALS. Here is the latest research on genomic instability associated with aging.

July 2, 2020
Review
Open Access

Centrosome dysfunction: a link between senescence and tumor immunity

Signal Transduction and Targeted Therapy
Qi WuSi Sun
July 2, 2020
Review
Open Access

Bibliometric Analysis of Research on Telomere Length in Children: A Review of Scientific Literature

International Journal of Environmental Research and Public Health
Desirée Valera-GranEva-María Navarrete-Muñoz
July 8, 2020
Preprint
Open Access

Age Influences on the Molecular Presentation of Tumours

BioRxiv : the Preprint Server for Biology
July 9, 2020
Review

Inborn Errors of Adaptive Immunity in Down Syndrome

Journal of Clinical Immunology
Ruud H J Verstegen, Maaike A A Kusters
July 8, 2020

Nutrient Control of mRNA Translation

Annual Review of Nutrition
Xin Erica ShuShu-Bing Qian
July 2, 2020

Body size, inbreeding, and lifespan in domestic dogs

Conservation Genetics
Jennifer YordyAdam R Boyko
July 8, 2020
Review
Open Access

The Nuclear Lamina: Protein Accumulation and Disease

Biomedicines
Carla Almendáriz-PalaciosChristopher H Eskiw
July 11, 2020
Review

Pathogenic Mechanisms of Somatic Mutation and Genome Mosaicism in Aging

Cell
Jan Vijg, Xiao Dong
July 9, 2020
Review
Open Access

The Impact of Single-Cell Genomics on Adipose Tissue Research

International Journal of Molecular Sciences
Alana DeutschKosaku Shinoda
July 6, 2020
Open Access

Persistent telomere cohesion protects aged cells from premature senescence

Nature Communications
Kameron AzarmSusan Smith
July 13, 2020

Epigenome-wide association studies in Alzheimer's disease; Achievements and challenges

Brain Pathology
Daniel L A van den HoveEhsan Pishva
July 5, 2020
Preprint
Open Access

STAMP: a multiplex sequencing method for simultaneous evaluation of mitochondrial DNA heteroplasmies and content

BioRxiv : the Preprint Server for Biology
Zhenglong GuR. Zhang
July 6, 2020
Preprint
Open Access

Copy numbers of 45S and 5S ribosomal DNA arrays lack meaningful correlation in humans

BioRxiv : the Preprint Server for Biology
A. N. HallChristine Queitsch
July 8, 2020

Older molecular brain age in severe mental illness

Molecular Psychiatry
Chien-Wei LinEtienne Sibille

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