Gfral Neurons Reduce Food Intake

GFRAL is a receptor for growth differentiation factor 15 (GDF15). These proteins play a role in regulating inflammatory pathways, as well as cell repair, apoptosis, cell growth, and body-weight regulation. Here is the latest research on the role of GFRAL-expressing neurons in reducing food intake.

October 17, 2021

Cholecystokinin acts in the dorsomedial hypothalamus of young male rats to suppress appetite in a nitric oxide-dependent manner.

Neuroscience Letters
Victoria A Rust, Karen M Crosby
October 17, 2021

AgRP neuronal activity across feeding-related behaviours.

The European Journal of Neuroscience
Ayden GouveiaSophie M Steculorum
October 16, 2021

Disease-modifying treatment of Parkinson's disease by phytochemicals: targeting multiple pathogenic factors.

Journal of Neural Transmission
Makoto NaoiMasayo Shamoto-Nagai
October 15, 2021

Oestrogen engages brain MC4R signalling to drive physical activity in female mice.

William C KrauseHolly A Ingraham
October 14, 2021

Functional heterogeneity of POMC neurons relies on mTORC1 signaling.

Cell Reports
Nicolas SaucisseDaniela Cota
October 13, 2021

Synthesis of Proposed Structure of Aaptoline A, a Marine Sponge-Derived 7,8-Dihydroxyquinoline, and Its Neuroprotective Properties in C. elegans.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Soobin KimYoung Taek Han
October 13, 2021
Open Access

Targeting Oxidative Stress with Antioxidant Duotherapy after Experimental Traumatic Brain Injury.

International Journal of Molecular Sciences
Jenni KyyriäinenAsla Pitkänen
October 13, 2021

Parkinsonism and motor neuron disorders: Lessons from Western Pacific ALS/PDC.

Journal of the Neurological Sciences
Peter S Spencer
October 12, 2021

Time-dependent changes in hippocampal and striatal glycogen long after maze training in male rats.

Neurobiology of Learning and Memory
Claire J ScavuzzoDonna L Korol
October 11, 2021

A Comprehensive Review of the Neuroscience of Ingestion: The Physiological Control of Eating - Signals, Neurons and Networks.

Physiological Reviews
Willis K Samson, Gina L C Yosten
October 10, 2021

Time and metabolic state dependent effects of GLP-1R agonists on NPY/AgRP and POMC neuronal activity in-vivo.

Molecular Metabolism
Yanbin DongKevin W Williams
October 8, 2021
Open Access

Food-Origin Mycotoxin-Induced Neurotoxicity: Intend to Break the Rules of Neuroglia Cells.

Oxidative Medicine and Cellular Longevity
Xingyao PeiDaowen Li
October 7, 2021

Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
Wudi HaoCuihong Jin
October 5, 2021

The potential role of Piper guineense (black pepper) in managing geriatric brain aging: a review.

Critical Reviews in Food Science and Nutrition
Oluwaseun Hannah AdemuyiwaOluwafemi Ayodeji Adebo

Sign up to follow this feed and discover related papers.

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.


Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.

Astrocytes & Amyloid

Astrocytes are thought to play a role in amyloid production and have been implicated in neurodegenerative diseases such as Alzheimer’s disease. Here is the latest research on the relationship between astrocytes and amyloid.

Astrocytes & Huntington’s Disease

Astrocytes are abundant within the central nervous system and their dysfunction has been thought to be an important contributor to some neurodegenerative diseases, in particular Huntington’s disease. Damage to these cells may make neurons more susceptible to degeneration. Here is the latest research on astrocytes and Huntington’s disease.

Astrocytes & Neurodegeneration

Astrocytes are important for the health and function of the central nervous system. When these cells stop functioning properly, either through gain of function or loss of homeostatic controls, neurodegenerative diseases can occur. Here is the latest research on astrocytes and neurodegeneration.

Astrocytes in Repair & Regeneration

Astrocytes are glial cells found within the CNS and are able to regenerate new neurons. They become activated during CNS injury and disease. The activation leads to the transcription of new genes and the repair and regeneration of neurons. Discover the latest research on astrocytes in repair and regeneration here.


Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.

Basal Forebrain & Food Avoidance

Neurons in the basal forebrain play specific roles in regulating feeding. Here are the latest discoveries pertaining to the basal forebrain and food avoidance.

Blood Brain Barrier & Cytokines

Some cytokines are able to cross the blood brain barrier through transport systems and enter the cerebrospinal fluid and interstitial fluid spaces. Here is the latest research on cytokines crossing the blood brain barrier and how this can affect tissues within the CNS.

© 2021 Meta ULC. All rights reserved