Gfral Neurons Reduce Food Intake

GFRAL is a receptor for growth differentiation factor 15 (GDF15). These proteins play a role in regulating inflammatory pathways, as well as cell repair, apoptosis, cell growth, and body-weight regulation. Here is the latest research on the role of GFRAL-expressing neurons in reducing food intake.

October 17, 2021

Cholecystokinin acts in the dorsomedial hypothalamus of young male rats to suppress appetite in a nitric oxide-dependent manner.

Neuroscience Letters
Victoria A Rust, Karen M Crosby
October 17, 2021

AgRP neuronal activity across feeding-related behaviours.

The European Journal of Neuroscience
Ayden GouveiaSophie M Steculorum
October 16, 2021
Review

Disease-modifying treatment of Parkinson's disease by phytochemicals: targeting multiple pathogenic factors.

Journal of Neural Transmission
Makoto NaoiMasayo Shamoto-Nagai
October 15, 2021

Oestrogen engages brain MC4R signalling to drive physical activity in female mice.

Nature
William C KrauseHolly A Ingraham
October 14, 2021

Functional heterogeneity of POMC neurons relies on mTORC1 signaling.

Cell Reports
Nicolas SaucisseDaniela Cota
October 13, 2021

Synthesis of Proposed Structure of Aaptoline A, a Marine Sponge-Derived 7,8-Dihydroxyquinoline, and Its Neuroprotective Properties in C. elegans.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Soobin KimYoung Taek Han
October 13, 2021
Open Access

Targeting Oxidative Stress with Antioxidant Duotherapy after Experimental Traumatic Brain Injury.

International Journal of Molecular Sciences
Jenni KyyriäinenAsla Pitkänen
October 13, 2021
Review

Parkinsonism and motor neuron disorders: Lessons from Western Pacific ALS/PDC.

Journal of the Neurological Sciences
Peter S Spencer
October 12, 2021

Time-dependent changes in hippocampal and striatal glycogen long after maze training in male rats.

Neurobiology of Learning and Memory
Claire J ScavuzzoDonna L Korol
October 11, 2021

A Comprehensive Review of the Neuroscience of Ingestion: The Physiological Control of Eating - Signals, Neurons and Networks.

Physiological Reviews
Willis K Samson, Gina L C Yosten
October 10, 2021

Time and metabolic state dependent effects of GLP-1R agonists on NPY/AgRP and POMC neuronal activity in-vivo.

Molecular Metabolism
Yanbin DongKevin W Williams
October 8, 2021
Review
Open Access

Food-Origin Mycotoxin-Induced Neurotoxicity: Intend to Break the Rules of Neuroglia Cells.

Oxidative Medicine and Cellular Longevity
Xingyao PeiDaowen Li
October 7, 2021

Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
Wudi HaoCuihong Jin
October 5, 2021

The potential role of Piper guineense (black pepper) in managing geriatric brain aging: a review.

Critical Reviews in Food Science and Nutrition
Oluwaseun Hannah AdemuyiwaOluwafemi Ayodeji Adebo

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