GFRAL/GDF15 Signaling

GFRAL is a receptor for growth differentiation factor 15 (GDF15). These proteins play a role in regulating inflammatory pathways, as well as cell repair, apoptosis, and cell growth. Here is the latest research on GFRAL/GDF15-mediated signal transduction.

December 22, 2020
Review
Open Access

Role of Growth Differentiation Factor 15 in Lung Disease and Senescence: Potential Role Across the Lifespan

Frontiers in Medicine
Faeq Al-MudaresKrithika Lingappan
January 10, 2021

GDF15 as a biomarker of ageing

Experimental Gerontology
Huan LiuYan Li
December 19, 2020
Open Access

Increased urinary markers of kidney damage in the institutionalized frail elderly due to recurrent urinary tract infections

Therapeutic Advances in Urology
María-Fernanda Lorenzo-GómezMaría-Begoña García-Cenador
December 22, 2020
Open Access

Full Issue PDF

JACC. Case Reports
December 19, 2020

AMPK mediates energetic stress-induced liver GDF15

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Logan K TownsendDavid C Wright
December 19, 2020

News section PDF

The Veterinary Record
January 13, 2021
Open Access

GDF15 promotes glioma stem cell-like phenotype via regulation of ERK1/2-c-Fos-LIF signaling

Cell Death Discovery
Shan ZhuJingtao Chen
January 11, 2021

Serum NT-proBNP levels are associated with cognitive functions in hemodialysis patients

Seminars in Dialysis
Gulsum AkkusOzkan Gungor
December 16, 2020
Review

Growth differentiation factor-15 and its role in diabetes and cardiovascular disease

Cytokine & Growth Factor Reviews
Adrian C Eddy, Aaron J Trask
December 15, 2020

Biomarkers for Risk Assessment in Atrial Fibrillation

Clinical Chemistry
David D BergDavid A Morrow
January 18, 2021
Open Access

BMP-9 and LDL crosstalk regulates ALK-1 endocytosis and LDL transcytosis in endothelial cells

The Journal of Biological Chemistry
Bo TaoWilliam C Sessa
January 10, 2021
Open Access

Growth Differentiation Factor 15: A Biomarker with High Clinical Potential in the Evaluation of Kidney Transplant Candidates

Journal of Clinical Medicine
Marina de Cos GomezEmilio Rodrigo Calabia
January 19, 2021
Preprint
Open Access

Post-biopsy cell-free DNA from blood: an open window on primary prostate cancer genetics and biology

ResearchSquare
Marinella CorbettaStefano Duga
January 12, 2021

Association of GDF15 with inflammation and physical function during aging and recovery after acute hospitalization: a longitudinal study of older patients and age-matched controls

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Juliette TavenierJan O Nehlin
December 22, 2020
Open Access

Hepatic stellate cells in hepatocellular carcinoma promote tumor growth via growth differentiation factor 15 production

Gastroenterology
Yuta MyojinTetsuo Takehara
January 8, 2021
Open Access

Hippocampal and Prefrontal Cortical Brain Tissue Levels of Irisin and GDF15 Receptor Subunits in Children

Molecular Neurobiology
Travis C JacksonPatrick M Kochanek

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