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GLP-1 Signaling

GLP-1 Signaling diagram by ibreakstock, Shutterstock
ibreakstock, Shutterstock

GLP-1 signaling pathway has been well studied for its role in regulating glucose homeostasis, as well as its beneficial effects in energy and nutrient metabolism. Discover the latest research on this signaling pathway here.

Top 20 most recent papers

A PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD Lipid

DiabetesJanuary 25, 2020
Mario Luca MorieriAlessandro Doria

Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality: a prospective study

DiabetologiaJanuary 25, 2020
Amra JujićMartin Magnusson
Nature Communications

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Nature CommunicationsJanuary 26, 2020
Julia AstDavid J Hodson

A Single Bout of One-legged Exercise to Local Exhaustion Decreases Insulin Action in Non-exercised Muscle Leading to Decreased Whole-body Insulin Action

DiabetesJanuary 25, 2020
Dorte E SteenbergJørgen F P Wojtaszewski
Scientific Reports

Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects

Scientific ReportsJanuary 24, 2020
Mitsuhiro KawakuboTakayoshi Suganami

Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects with Hepatic Steatosis

DiabetesJanuary 25, 2020
Malte P SuppliFilip K Knop

Liver ChREBP Protects Against Fructose-induced Glycogenic Hepatotoxicity by Regulating L-type Pyruvate Kinase

DiabetesJanuary 25, 2020
Jian-Hui ShiWeiping J Zhang
International Journal of Obesity : Journal of the International Association for the Study of Obesity

Liraglutide improves memory in obese patients with prediabetes or early type 2 diabetes: a randomized, controlled study

International Journal of Obesity : Journal of the International Association for the Study of ObesityJanuary 23, 2020
Francesco VadiniFrancesca Santilli

Comprehensive Glycomic Analysis Reveals that Human Serum Albumin Glycation Specifically Affects the Pharmacokinetics and Efficacy of Different Anticoagulant Drugs in Diabetes

DiabetesJanuary 25, 2020
Hongyan QiuQunye Zhang

Troponin T parallels Structural Nerve Damage in Type 2 Diabetes a Cross-sectional Study Using Magnetic Resonance Neurography

DiabetesJanuary 25, 2020
Johann M E JendeFelix T Kurz
Clinical Diabetes and Endocrinology

Achieving postprandial glucose control with lixisenatide improves glycemic control in patients with type 2 diabetes on basal insulin: a post-hoc analysis of pooled data

Clinical Diabetes and EndocrinologyJanuary 21, 2020
Jaime A DavidsonLawrence A Leiter
Clinical Diabetes : a Publication of the American Diabetes Association

Clinical Use of IDegLira: Initiation to Titration After Basal Insulin

Clinical Diabetes : a Publication of the American Diabetes AssociationJanuary 25, 2020
Mark Warren, Donna Steel
Diabetes Care

No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes

Diabetes CareJanuary 18, 2020
Natasha C BergmannFilip K Knop

Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats

DiabetesJanuary 25, 2020
Le QiZhaoli Sun

Clinical Considerations When Initiating and Titrating Insulin Degludec/Liraglutide (IDegLira) in People with Type 2 Diabetes

DrugsJanuary 22, 2020
Stewart HarrisTina Vilsbøll

Rapid changes in neuroendocrine regulation may contribute to reversal of type 2 diabetes after gastric bypass surgery

EndocrineJanuary 27, 2020
Petros KatsogiannosJan W Eriksson
Molecular Nutrition & Food Research

Flavone Hispidulin Stimulates Glucagon-Like peptide-1 Secretion and Ameliorates Hyperglycemia in Streptozotocin-Induced Diabetic Mice

Molecular Nutrition & Food ResearchJanuary 23, 2020
Yao WangDongmin Liu
Metabolism: Clinical and Experimental

Twelve weeks of exenatide treatment increases [18 F]fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males

Metabolism: Clinical and ExperimentalJanuary 27, 2020
Laura G M JanssenPatrick C N Rensen
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology

Dimerization/oligomerization of the extracellular domain of the GLP-1 receptor and the negative cooperativity in its ligand binding revealed by the improved NanoBiT

FASEB Journal : Official Publication of the Federation of American Societies for Experimental BiologyJanuary 24, 2020
Xiaohan SongNan Wang

Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared to Type 1 Diabetes Mellitus

DiabetesJanuary 25, 2020
Anne Jörns A JSigurd Lenzen S L

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