GPCRs & Homeostasis
GPCRs are membrane receptors implicated in the pathophysiology of various diseases. Several GPCRs, including GLP-1 receptor, glucagon receptor, and adiponectin receptor, are also involved in metabolic regulation and homeostasis. Here is the latest research.
β1-adrenoceptor-stimulated lactate production in cultured astrocytes is predominantly glycogen-independent
Enigmatic Histamine Receptor H4 for Potential Treatment of Multiple Inflammatory, Autoimmune, and Related Diseases
Endocrine, Metabolic and Pharmacological Effects of Thyronamines (TAM), Thyroacetic Acids (TA) and Thyroid Hormone Metabolites (THM) - Evidence from in vitro, Cellular, Experimental Animal and Human Studies
Dopamine D2 autoreceptor interactome: Targeting the receptor complex as a strategy for treatment of substance use disorder
Role of GPRC6A in Regulating Hepatic Energy Metabolism in Mice
Evidence for NADPH oxidase activation by GPR40 in pancreatic β-cells
A common human variant of GIPR improves systemic glucose homeostasis in a sexual dimorphic manner
7α,25-dihydroxycholesterol protects against liver X receptor-mediated steatosis through GPR183/EBI2 in human and mouse hepatocytes
Discovery and pharmacology of the covalent GLP-1 receptor (GLP-1R) allosteric modulator BETP: A novel tool to probe GLP-1R pharmacology
Comparative and Evolutionary Physiology of Vasopressin/ Oxytocin-Type Neuropeptide Signaling in Invertebrates
Evolutionary links between intra- and extracellular acid-base regulation in fish and other aquatic animals
The Multi-Faced Extracellular Vesicles in the Plasma of Chronic Kidney Disease Patients
Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A
A2A adenosine receptor antagonists: From caffeine to selective non-xanthines
Ceramide and Sphingosine 1-Phosphate in Liver Diseases
Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer
Selective stimulation of colonic L cells improves metabolic outcomes in mice
The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression
The Role of the Microbiome in Food Allergy: A Review
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