GPCRs Signaling Pathway

G-protein coupled receptors (GPCRs) are membrane receptors implicated in the pathophysiology of various diseases, including neurodegenerative disorders, infectious diseases, and cancer. Here is the latest research on GPCR signaling pathway.

January 16, 2022

Computational characterization of transducer recognition of β2 adrenergic receptor.

Biochemical and Biophysical Research Communications
Lifen ZhaoXi Cheng
January 16, 2022

Agonist-induced extracellular vesicles contribute to the transfer of functional bombesin receptor-subtype 3 to recipient cells.

Cellular and Molecular Life Sciences : CMLS
Zeyuan WangHua Xiao
January 16, 2022

Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin.

NPJ Science of Food
Naoki HaradaRyoichi Yamaji
January 15, 2022
Preprint
Open Access

BitterMatch: Recommendation systems for matching molecules with bitter taste receptors

BioRxiv : the Preprint Server for Biology
E. MargulisMasha Y Niv
January 15, 2022

Molecular mechanism of agonism and inverse agonism in ghrelin receptor.

Nature Communications
Jiao QinZhenhua Shao
January 14, 2022
Preprint
Open Access

Location bias contributes to functionally selective responses of biased CXCR3 agonists

BioRxiv : the Preprint Server for Biology
D. S. EigerSudarshan Rajagopal
January 15, 2022
Open Access

Differential voltage-dependent modulation of the ACh-gated K+ current by adenosine and acetylcholine.

PloS One
Ana Laura López-SerranoEloy G Moreno-Galindo
January 14, 2022

Dopamine D2L receptor density influences the recruitment of β-arrestin2 and Gi1 induced by antiparkinsonian drugs.

Neuropharmacology
Mattia FerraioloEmmanuel Hermans
January 14, 2022

Farnesylation and lipid unsaturation are critical for the membrane binding of the C-terminal segment of G-Protein Receptor Kinase 1.

Colloids and Surfaces. B, Biointerfaces
Marc-Antoine MilletteChristian Salesse
January 14, 2022

PM2.5 causes vascular hyperreactivity through the upregulation of the thromboxane A2 receptor and activation of MAPK pathways.

Environmental Science and Pollution Research International
Rong WangBei Qin
January 14, 2022
Open Access

Hyperoside attenuates non-alcoholic fatty liver disease in rats via cholesterol metabolism and bile acid metabolism.

Journal of Advanced Research
Songsong WangPeng Li
January 14, 2022

Mice Lacking Gpr75 are Hypophagic and Thin.

Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy
David R PowellMelanie K Shadoan
January 14, 2022

Peptide-Dependent Growth in Yeast via Fine-Tuned Peptide/GPCR-Activated Essential Gene Expression.

Biochemistry
Sonja Billerbeck, Virginia W Cornish
January 14, 2022

Apelin-13 Decreases Epithelial Sodium Channel (ENaC) Expression and Activity in Kidney Collecting Duct Cells.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology
Houda Ayari, Ahmed Chraibi
January 14, 2022

Design, Characterization, and Docking Studies of Some Novel Isatin Derivatives for Anticonvulsant and Antidepressant Activity.

Advances in Experimental Medicine and Biology
Konda SwathiP Naveena
January 13, 2022

GPR17 signaling activation by CHBC agonist induced cell death via modulation of MAPK pathway in glioblastoma.

Life Sciences
Phung NguyenMeenakshisundaram Kandhavelu

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