Hallervorden-Spatz Disease

Hallervorden-Spatz disease, also known as pantothenate kinase-associated neurodegeneration, is a rare neurodegenerative disease associated with iron accumulation in the brain. Here is the latest research.

March 25, 2020

Intellectual Disability, Falls and Gait Disturbances: A Misdiagnosis

European Journal of Case Reports in Internal Medicine
Noel Lorenzo VillalbaAbrar-Ahmad Zulfiqar
May 28, 2020
Open Access

Substantia nigra echogenicity is associated with serum ferritin, gender and iron-related genes in Parkinson's disease

Scientific Reports
Kai LiChun-Feng Liu
January 14, 2021

Pathogenic mechanism and modeling of neuroferritinopathy

Cellular and Molecular Life Sciences : CMLS
Anna CozziSonia Levi
July 14, 2020
Open Access

A New Allelic Variant in the PANK2 Gene in a Patient with Incomplete HARP Syndrome

Journal of Movement Disorders
Myriam Ley MartosLorena Estepa Pedregosa
April 2, 2020
Case Report
Open Access

Idiopathic brain calcification in a patient with hereditary hemochromatosis

BMC Neurology
Stefania ScarliniElena Corradini
October 6, 2020
Open Access

Brain MRI Pattern Recognition in Neurodegeneration With Brain Iron Accumulation

Frontiers in Neurology
Jae-Hyeok LeeSusan J Hayflick
November 26, 2020

Abnormal Vasculature Development in Zebrafish Embryos with Reduced Expression of Pantothenate Kinase 2 Gene

Bulletin of Experimental Biology and Medicine
D KhatriD Finazzi
July 14, 2020
Open Access

MRI of neurodegeneration with brain iron accumulation

Current Opinion in Neurology
Stéphane LehéricyFanny Mochel
March 8, 2020
Open Access

NBIA: a network-based integrative analysis framework - applied to pathway analysis

Scientific Reports
Tin NguyenSorin Draghici
January 6, 2021
Open Access

Exploring Yeast as a Study Model of Pantothenate Kinase-Associated Neurodegeneration and for the Identification of Therapeutic Compounds

International Journal of Molecular Sciences
Camilla Ceccatelli BertiPaola Goffrini
August 9, 2020
Open Access

Impaired proteasome activity and neurodegeneration with brain iron accumulation in FBXO7 defect

Annals of Clinical and Translational Neurology
Marta Correa-VelaCarmen Espinós
March 19, 2020
Open Access

Genotype-phenotype correlations of adult-onset PLA2G6-associated Neurodegeneration: case series and literature review

BMC Neurology
Yung-Tsai ChuChin-Hsien Lin
May 28, 2020
Open Access

Harmful Iron-Calcium Relationship in Pantothenate kinase Associated Neurodegeneration

International Journal of Molecular Sciences
Paolo SantambrogioSonia Levi
August 28, 2020

Cerebral blood flow in dystonia due to pantothenate kinase-associated neurodegeneration

The Neuroradiology Journal
Peter StoeterPamela Bido
July 25, 2020
Open Access

PKAN neurodegeneration and residual PANK2 activities in patient erythrocytes

Annals of Clinical and Translational Neurology
Maike WerningUlrich Salzer
November 3, 2020
Open Access

Novel dominant MPAN family with a complex genetic architecture as a basis for phenotypic variability

Neurology. Genetics
Peter BaliczaMaria Judit Molnar
March 1, 2020
Open Access

A novel way to synthesize pantothenate in bacteria involves β-alanine synthase present in uracil degradation pathway

Mariana López-SámanoAlejandro García-de Los Santos
February 12, 2020
Open Access

Natural history and genotype-phenotype correlation of pantothenate kinase-associated neurodegeneration

CNS Neuroscience & Therapeutics
Xuting ChangYe Wu

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