Hematopoiesis In Aging

Hematopoiesis is the process by which a limited number of hematopoietic stem cells maintain a functioning blood and immune system. Aging of these stem cells leads to several functional changes, including alterations affecting self-renewal and differentiation. Here is the latest research.

December 18, 2020
Open Access

Immuno-Modulation of Hematopoietic Stem and Progenitor Cells in Inflammation

Frontiers in Immunology
Maiko SezakiHitoshi Takizawa
January 4, 2021

Neuroprotection through G-CSF: recent advances and future viewpoints

Pharmacological Reports : PR
Vikrant RahiPuneet Kumar
December 2, 2020
Open Access

Restoration of β-globin expression with optimally designed lentiviral vector for β-thalassemia treatment in Chinese patients

Human Gene Therapy
Wenjie OuyangChao Liu
December 15, 2020
Open Access

High platelet count is associated with low bone mineral density: The MrOS Sweden cohort

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
H L KristjansdottirC Lewerin
December 18, 2020

Clonal hematopoiesis: a risk factor for leukemia and cardiovascular disease?

Nederlands tijdschrift voor geneeskunde
I A van ZeventerG Huls
January 6, 2021
Open Access

Anti-Aging Physiological Roles of Aryl Hydrocarbon Receptor and Its Dietary Regulators

International Journal of Molecular Sciences
Eva SernaJose Vina
January 15, 2021
Open Access

Aging of human hematopoietic stem cells is linked to changes in Cdc42 activity

Amanda AmoahHartmut Geiger
January 5, 2021
Open Access

Generation of Dyskeratosis Congenita-like Hematopoietic Stem Cells through the Stable Inhibition of DKC1

Carlos Carrascoso-RubioGuillermo Guenechea
January 7, 2021
Open Access

Gene Therapy for Primary Immunodeficiency

Benjamin C Houghton, Claire Booth
January 14, 2021
Open Access

Inflammasomes and the Maintenance of Hematopoietic Homeostasis: New Perspectives and Opportunities

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Lijing YangJunping Wang
December 23, 2020
Open Access

Expansion of senescent megakaryocyte-lineage cells maintains CML cell leukemogenesis

Blood Advances
Yamato TanabeTomohisa Baba
January 5, 2021
Open Access

Mitigating oxygen stress enhances aged mouse hematopoietic stem cell numbers and function

The Journal of Clinical Investigation
Maegan L CapitanoHal E Broxmeyer
January 22, 2021

Establishment of a cell processing laboratory to support hematopoietic stem cell transplantation and chimeric antigen receptor (CAR)-T cell therapy.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
Somnath MukherjeeDavid Stroncek
December 2, 2020

Stathmin 1 deficiency induces erythro-megakaryocytic defects leading to macrocytic anemia and thrombocythemia in Stathmin 1 knock out mice

Blood Cells, Molecules & Diseases
Charmaine A Ramlogan-SteelGeorge F Atweh
December 17, 2020
Open Access

Bone Angiogenesis and Vascular Niche Remodeling in Stress, Aging, and Diseases

Frontiers in Cell and Developmental Biology
Sina StuckerAnjali P Kusumbe

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