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Hematopoiesis In Aging

Hematopoiesis In Aging diagram by undefined

Hematopoiesis is the process by which a limited number of hematopoietic stem cells maintain a functioning blood and immune system. Aging of these stem cells leads to several functional changes, including alterations affecting self-renewal and differentiation. Here is the latest research.

Top 20 most recent papers
Nature

Genetic predisposition to mosaic Y chromosome loss in blood

NatureNovember 20, 2019
Deborah J. ThompsonJohn R. B. Perry
210
2
1
1
1
Nature Medicine

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

Nature MedicineNovember 7, 2019
Vanessa FrodermannMatthias Nahrendorf
449
6
7
1
1
Science

Clonal hematopoiesis in human aging and disease

ScienceNovember 1, 2019
Siddhartha Jaiswal, Benjamin L Ebert
184
1
1
Blood

Clonal Dynamics and Clinical Implications of Post-Remission Clonal Hematopoiesis in Acute Myeloid Leukemia (AML)

BloodNovember 13, 2019
Tomoyuki TanakaKoichi Takahashi
1
bioRxiv

Mass spectrometry analysis of mouse hematopoietic stem cells and their progenitors reveals differential expression within and between proteome and transcriptome throughout adult and aged hematopoiesis

bioRxivNovember 9, 2019
Balyn W ZaroIrving L. Weissman
30
Blood

Donor Clonal Hematopoiesis Increases Risk of Acute Graft Versus Host Disease after Matched Related Transplantation in AML and MDS Patients

BloodNovember 13, 2019
Betul OranKoichi Takahashi
1
Cell Stem Cell

Identification of Functionally Distinct Mx1+αSMA+ Periosteal Skeletal Stem Cells

Cell Stem CellDecember 5, 2019
Laura C OrtinauDongsu Park
Scientific Reports

A Microfluidic Device to Enhance Viral Transduction Efficiency During Manufacture of Engineered Cellular Therapies

Scientific ReportsOctober 22, 2019
Nathan MooreKenneth Kotz
5
1
bioRxiv

The hematopoietic landscape at single-cell resolution reveals unexpected stem cell features in naked mole-rats

bioRxivNovember 29, 2019
Stephan EmmrichVera Gorbunova
79
Annual Review of Pathology

Cardiovascular Disease, Aging, and Clonal Hematopoiesis

Annual Review of PathologyNovember 5, 2019
Megan A EvansKenneth B Walsh
bioRxiv

In silico analysis of Missense Variants in Human MPL Gene Associated with Essential Thrombocythemia

bioRxivNovember 4, 2019
Sahar G. ElbagerMagdi Bayoumi
4
Blood

HDAC11 Deficiency or Inhibition Disrupts Oncogene-Induced Stress Hematopoiesis in Myeloproliferative Neoplasms

BloodNovember 21, 2019
Lan-Zhu YuePearlie Kay Epling-Burnette
bioRxiv

Sort-purification of human CD34+CD90+ cells reduces target cell population and improves lentiviral transduction

bioRxivNovember 26, 2019
Stefan RadtkeHans-Peter Kiem
1
Blood

Concordance for clonal hematopoiesis is limited in elderly twins

BloodOctober 25, 2019
Margarete Alice FabreGeorge S Vassiliou
Blood

Clonal hematopoiesis in elderly twins: concordance, discordance and mortality

BloodOctober 24, 2019
Jakob Werner HansenKirsten Grønbæk
1
Blood Advances

The transcriptome of CMML monocytes is highly inflammatory and reflects leukemia-specific and age-related alterations

Blood AdvancesOctober 22, 2019
Anca FranziniMichael Werner Nikolaus Deininger
3
Blood

Description of a Knock-In Mouse Model of JAK2V617F MPN Emerging from a Minority of Mutated Hematopoietic Stem Cells

BloodOctober 11, 2019
Olivier MansierChloé James
3
Annals of the New York Academy of Sciences

Adult stem cells and regenerative medicine-a symposium report

Annals of the New York Academy of SciencesOctober 26, 2019
Jennifer CableMark A Krasnow
2
Haematologica

Microenvironmental contributions to hematopoietic stem cell aging

HaematologicaDecember 5, 2019
Ya-Hsuan Ho, Simón Méndez-Ferrer
Leukemia

Elevated Hedgehog activity contributes to attenuated DNA damage responses in aged hematopoietic cells

LeukemiaNovember 14, 2019
Annika ScheffoldMartin D Burkhalter
5

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