Hereditary Demyelinating Diseases of the CNS

Hereditary demyelinating diseases of the central nervous systems are caused primarily due to inherited genetic conditions. Examples include Alexander, Canavan, and Pelizaeus-Merzbacher diseases. Here is the latest research.

January 15, 2022

OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease.

Npj Regenerative Medicine
Wonjin YunSeungkwon You
January 15, 2022

Elderly patients with suspected Charcot-Marie-Tooth disease should be tested for the TTR gene for effective treatments.

Journal of Human Genetics
Takaki TaniguchiHiroshi Takashima
January 15, 2022

Chronic lithium administration in a mouse model for Krabbe disease.

JIMD Reports
Ambra Del GrossoMarco Cecchini
January 15, 2022
Case Report

Low donor chimerism may be sufficient to prevent demyelination in adrenoleukodystrophy.

JIMD Reports
Takahiro IkedaTakanori Yamagata
January 15, 2022

Relationship between blood-brain permeability and antibodies against aquaporins in neuromyelitis optica spectrum disorders and multiple sclerosis patients.

Neurologia i neurochirurgia polska
Michalina Jasiak-ZatońskaAlicja Kalinowska-Łyszczarz
January 14, 2022

Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis.

Science
Kjetil BjornevikAlberto Ascherio
January 14, 2022

Central Nervous System Demyelination Related to Tumour Necrosis Factor Alpha Inhibitor.

Multiple Sclerosis Journal - Experimental, Translational and Clinical
Shin Yee Chey, Allan G Kermode
January 12, 2022
Preprint
Open Access

Single-nucleus RNA-seq of normal-appearing brain regions in relapsing-remitting vs. secondary progressive multiple sclerosis

BioRxiv : the Preprint Server for Biology
Yasuyuki KiharaJ. Chun
January 12, 2022
Review
Open Access

Abnormal Ca2+ Signals in Reactive Astrocytes as a Common Cause of Brain Diseases.

International Journal of Molecular Sciences
Schuichi KoizumiJunichi Nabekura
January 12, 2022
Review
Open Access

Human iPSC-Derived Astrocytes: A Powerful Tool to Study Primary Astrocyte Dysfunction in the Pathogenesis of Rare Leukodystrophies.

International Journal of Molecular Sciences
Angela LanciottiElena Ambrosini
January 12, 2022
Open Access

Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment.

Communications Biology
Le Thi My LeAmer Alam
January 12, 2022
Case Report

COVID-Related Leukoencephalopathy: Unusual MRI Features and Comparability to Delayed Post Hypoxic Ischemic Encephalopathy.

Radiology Case Reports
Manzoor AhmedAbd Al Kareem Adi
January 10, 2022

Prion-like α-synuclein pathology in the brain of infants with Krabbe disease.

Brain : a Journal of Neurology
Christopher HattonDaniel Erskine

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