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Hippo Pathway-YAP/TAZ

Hippo Pathway-YAP/TAZ diagram by ellepigrafica, Shutterstock
ellepigrafica, Shutterstock

The Hippo pathway regulates diverse cellular phenotypes such as organ size, angiogenesis, tissue regeneration and self-renewal. YAP and TAZ important transcriptional coactivators downstream of hippo signaling. Discover the latest research on Hippo Pathway-YAP/TAZ here.

Top 20 most recent papers
Cancer Cell

Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

Cancer CellJanuary 15, 2020
Kari J KurppaPasi A Jänne
87
Cells

Mechanical Forces as Determinants of Disseminated Metastatic Cell Fate

CellsJanuary 23, 2020
Marco Montagner, Sirio Dupont
Hepatology : Official Journal of the American Association for the Study of Liver Diseases

Cooperation between MYC and β-catenin in liver tumorigenesis requires Yap/Taz

Hepatology : Official Journal of the American Association for the Study of Liver DiseasesJanuary 23, 2020
Andrea BissoBruno Amati
1
bioRxiv

Division of labor between YAP and TAZ in non-small cell lung cancer

bioRxivJanuary 13, 2020
Michal ShakedEytan Ruppin
9
Molecular Biology of the Cell

Mechanical stress triggers nuclear remodeling and the formation of Transmembrane Actin Nuclear lines with associated Nuclear Pore Complexes

Molecular Biology of the CellJanuary 23, 2020
Laura M HoffmanMary C Beckerle
Scientific Reports

Regulation of Gdf5 expression in joint remodelling, repair and osteoarthritis

Scientific ReportsJanuary 15, 2020
Karolina KaniaCosimo De Bari
1
Cancers

Resistance to MET/VEGFR2 Inhibition by Cabozantinib Is Mediated by YAP/TBX5-Dependent Induction of FGFR1 in Castration-Resistant Prostate Cancer

CancersJanuary 23, 2020
Filippos KoinisGary Gallick
PLoS Biology

Yap suppresses T-cell function and infiltration in the tumor microenvironment

PLoS BiologyJanuary 14, 2020
Eleni StampouloglouXaralabos Varelas
25
Molecular Cancer

Downregulation of MYPT1 increases tumor resistance in ovarian cancer by targeting the Hippo pathway and increasing the stemness

Molecular CancerJanuary 14, 2020
Sandra Muñoz-GalvánAmancio Carnero
14
Journal of Cell Science

DLC1 is a direct target of activated YAP/TAZ that drives collective migration and sprouting angiogenesis

Journal of Cell ScienceJanuary 23, 2020
Miesje van der StoelStephan Huveneers
Reproductive Sciences

Ligands, Receptors, and Transcription Factors that Mediate Inter-Cellular and Intra-Cellular Communication during Ovarian Follicle Development

Reproductive SciencesJanuary 16, 2020
Beatriz Peñalver BernabéLonnie D Shea
2
bioRxiv

A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors

bioRxivJanuary 22, 2020
Anjali BajpaiPradip Sinha
Journal of Molecular and Cellular Cardiology

Osteoprotegerin promotes intimal hyperplasia and contributes to in-stent restenosis: Role of an αVβ3/FAK dependent YAP pathway

Journal of Molecular and Cellular CardiologyJanuary 21, 2020
Yuhu HeShenghua Zhou
bioRxiv

Mechanical Regulation of Microvascular Angiogenesis

bioRxivJanuary 15, 2020
Marissa A RuehleNick J Willett
20
Biochemical and Biophysical Research Communications

Increased hydrostatic pressure induces nuclear translocation of DAF-16/FOXO in C. elegans

Biochemical and Biophysical Research CommunicationsJanuary 20, 2020
Naoshi WatanabeAtsushi Higashitani
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association

The curcumin analogue WZ35 affects glycolysis inhibition of gastric cancer cells through ROS-YAP-JNK pathway

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research AssociationJanuary 21, 2020
Tongke ChenLihua Wang
International Journal of Clinical and Experimental Pathology

Expression of miR-141 and YAP1 in gastric carcinoma and modulation of cancer cell proliferation and apoptosis

International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Fangchao DuGang Wen
International Journal of Clinical and Experimental Pathology

Yes-associated protein 1 promotes bladder cancer invasion by regulating epithelial-mesenchymal transition

International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Xingxing ChenWanlong Tan
1
International Journal of Clinical and Experimental Pathology

Clinical significance of AJUBA, YAP1, and MMP14 expression in esophageal squamous cell carcinoma

International Journal of Clinical and Experimental PathologyJanuary 18, 2020
Qing ZhangYuehong Li
Aging

SRV2 promotes mitochondrial fission and Mst1-Drp1 signaling in LPS-induced septic cardiomyopathy

AgingJanuary 18, 2020
Xiuling ShangRongguo Yu

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