Histone Acetyltransferases

Histone acetyltransferases are important chromatin modifying enzymes that catalyze acetylation of specific lysine residues in histone and nonhistone substrates to regulate gene expression. Here is the latest research.


January 8, 2021

ACTL6A promotes repair of cisplatin-induced DNA damage, a new mechanism of platinum resistance in cancer

Proceedings of the National Academy of Sciences of the United States of America
Yang XiaoWeei-Chin Lin
December 18, 2020

Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe.

International Journal of Biological Macromolecules
Adam KositzkeJiaoyang Jiang
December 16, 2020

Screening and identification of metacaspase inhibitors, evaluation of inhibition mechanism and trypanocidal activity

Antimicrobial Agents and Chemotherapy
Brian PérezVanina E Alvarez
January 12, 2021

PRMT5 and Tip60 Modify FOXP3 Function in Tumor Immunity

Critical Reviews in Immunology
Peeyush N GoelMark I Greene
January 4, 2021
Review

Sirtuins and the circadian clock interplay in cardioprotection: focus on sirtuin 1

Cellular and Molecular Life Sciences : CMLS
Sanjeev Kumar SoniRussel J Reiter
January 15, 2021

The GCN5: its biological functions and therapeutic potentials

Clinical Science
Md Ezazul HaqueDong-Kug Choi
January 21, 2021
Open Access

Substrate Scope for Human Histone Lysine Acetyltransferase KAT8.

International Journal of Molecular Sciences
Giordano ProiettiJasmin Mecinović
December 29, 2020
Open Access

Classification and phylogeny for the annotation of novel eukaryotic GNAT acetyltransferases

PLoS Computational Biology
Bojan KrtenicNathalie Reuter
January 16, 2021
Review
Open Access

Control of Mesenchymal Stromal Cell Senescence by Tryptophan Metabolites

International Journal of Molecular Sciences
Kenneth K Wu
January 8, 2021
Open Access

A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence

Science Translational Medicine
Wei WangGuang-Hui Liu
December 19, 2020

The biochemical and genetic discovery of the SAGA complex

Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms
Patrick A GrantShelley L Berger
January 1, 2021
Open Access

The negative role of histone acetylation in cobalt chloride-induced neurodegenerative damages in SHSY5Y cells

Ecotoxicology and Environmental Safety
Zhenkun GuoHuangyuan Li
January 8, 2021
Review
Open Access

Targeting Epigenetic 'Readers' with Natural Compounds for Cancer Interception

Journal of Cancer Prevention
Elisabetta DamianiRoderick H Dashwood
December 17, 2020

The CBP/p300 histone acetyltransferases function as plant-specific MEDIATOR subunits in Arabidopsis

Journal of Integrative Plant Biology
Jing GuoXin-Jian He
January 7, 2021
Review
Open Access

Neuroblastoma and the epigenome

Cancer Metastasis Reviews
Irfete S Fetahu, Sabine Taschner-Mandl
December 31, 2020
Open Access

Dysregulation of intercellular signaling by MOF deletion leads to liver injury

The Journal of Biological Chemistry
Hongwei LeiYali Dou
January 13, 2021
Open Access

Targeting p300/CBP axis in lethal prostate cancer

Cancer Discovery
Jonathan WeltiJohann S de Bono

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