Histone Deacetylases

Histone deacetylases (HDACs) are a class of chromatin modifying enzymes that remove specific acetyl groups from histones, allowing the histones to wrap DNA more tightly, thus leading to alterations in gene expression. Here is the latest research. 


September 24, 2020

Advances in chemical priming to enhance abiotic stress tolerance in plants

Plant & Cell Physiology
Kaori SakoMotoaki Seki
September 23, 2020
Review

Recent progress on HDAC inhibitors with dual targeting capabilities for cancer treatment

European Journal of Medicinal Chemistry
Xiaopeng PengJianjun Chen
September 19, 2020

Epigenetic Dysregulation in Advanced Kidney Cancer: Opportunities for Therapeutic Interventions

The Cancer Journal
Austin GoldsamtRoberto Pili
September 22, 2020
Open Access

Epigenetic modulation of the MAPK pathway prevents isoflurane-induced neuronal apoptosis and cognitive decline in aged rats

Experimental and Therapeutic Medicine
Lei HuangZhong-Yuan Xia
September 25, 2020

Induced protein degradation of histone deacetylases 3 (HDAC3) by proteolysis targeting chimera (PROTAC)

European Journal of Medicinal Chemistry
Fangyuan CaoFrank J Dekker
September 20, 2020
Retraction
Open Access

Retraction: Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator

The Journal of Biological Chemistry
Sai Murali Krishna PulukuriJasti S Rao
September 24, 2020

Association Between Histone Deacetylase Activity and Vitamin D-Dependent Gene Expressions in Relation to Sulforaphane in Human Colorectal Cancer Cell

Journal of the Science of Food and Agriculture
Sharmin HossainRichard J Wood
September 21, 2020

MiR-520d-5p modulates chondrogenesis and chondrocyte metabolism through targeting HDAC1

Aging
Jiajia LuAimin Chen
September 25, 2020

Targeting HDAC3 in the DBA2/J spontaneous mouse model of glaucoma

Experimental Eye Research
Heather M SchmittRobert W Nickells
September 25, 2020

Epigenetic marks and their relationship with BDNF in the brain of suicide victims

PloS One
Paulina MisztakMagdalena Sowa-Kućma
September 24, 2020

Label-Free Quantitative Phosphoproteomics Reveals Signaling Dynamics Involved in Embryogenic Competence Acquisition in Sugarcane

Journal of Proteome Research
Felipe A AlmeidaVanildo Silveira
September 18, 2020
Open Access

AGL15 Controls the Embryogenic Reprogramming of Somatic Cells in Arabidopsis through the Histone Acetylation-Mediated Repression of the miRNA Biogenesis Genes

International Journal of Molecular Sciences
Katarzyna NowakMałgorzata D Gaj
September 24, 2020
Open Access

Combination of ACY-241 and JQ1 Synergistically Suppresses Metastasis of HNSCC via Regulation of MMP-2 and MMP-9

International Journal of Molecular Sciences
Ha Young ChoSo Hee Kwon

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