HIV-1 Reverse Transcriptase

HIV-1 reverse transcriptase is among the earliest HIV proteins identified and is involved in viral replication. More than half of investigational long-acting antivirals target hiv-1 reverse transcriptase and/or integrase (hiv-1 in). Discover the latest research here.

April 30, 2020

Small Conformational Changes Underlie Evolution of Resistance to NNRTI in HIV Reverse Transcriptase

Biophysical Journal
Ashutosh SrivastavaSomdatta Sinha
July 1, 2020
Open Access

The Epidemiological and Clinical Characteristics of 81 Children with COVID-19 in a Pandemic Hospital in Turkey: an Observational Cohort Study

Journal of Korean Medical Science
Muhammet Furkan KorkmazZeliha Banu Kılıç
June 20, 2020

Probing the interaction between HIV-1 protease and the homodimeric p66/p66' reverse transcriptase precursor by double electron-electron resonance EPR spectroscopy

Chembiochem : a European Journal of Chemical Biology
Thomas SchmidtG Marius Clore
June 5, 2020
Preprint
Open Access

SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells

BioRxiv : the Preprint Server for Biology
C. MartinatAlessia Zamborlini
April 16, 2020

Genetic diversity and drug resistance of HIV-1 CRF55_01B in Guangdong, China

Current HIV Research
Guolong YuPeng Lin
July 10, 2020

Murine leukemia virus P50 protein counteracts APOBEC3 by blocking its packaging

Journal of Virology
Wenming ZhaoSusan R Ross
April 27, 2020

Quantifying the antiviral effect of APOBEC3 on HIV-1 infection in humanized mouse model

Journal of Theoretical Biology
Tatsuya KurusuShingo Iwami
April 14, 2020
Open Access

TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner

PLoS Pathogens
Molly OhainleMichael Emerman
May 25, 2020
Preprint
Open Access

AIDCOV: An Interpretable Artificial Intelligence Model for Detection of COVID-19 from Chest Radiography Images

MedRxiv : the Preprint Server for Health Sciences
M. ZokaeinikooPooyan Kazemian
May 8, 2020

Fluorescent Tricyclic Cytidine Analogues as Substrates for Retroviral Reverse Transcriptases

ChemPlusChem
M Benjamin Turner, Byron W Purse
April 30, 2020
Open Access

APOBEC3C Tandem Domain Proteins Create Super Restriction Factors against HIV-1

MBio
Mollie M McDonnellMichael Emerman
May 31, 2020
Preprint
Open Access

Genetically flexible but conserved: a new essential motif in the C-ter domain of HIV-1 group M integrases

BioRxiv : the Preprint Server for Biology
M. KanjaD. Lener

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