HIV-1 Reverse Transcriptase

HIV-1 reverse transcriptase is among the earliest HIV proteins identified and is involved in viral replication. More than half of investigational long-acting antivirals target hiv-1 reverse transcriptase and/or integrase (hiv-1 in). Discover the latest research here.

October 23, 2021
Case Report

COVID-19, HIV-Associated Cryptococcal Meningitis, Disseminated Tuberculosis and Acute Ischaemic Stroke: A Fatal Foursome.

Infection and Drug Resistance
Felix BongominFrederick Nakwagala
October 23, 2021

Intrathecal inflammatory responses in the absence of SARS-CoV-2 nucleic acid in the CSF of COVID-19 hospitalized patients.

Journal of the Neurological Sciences
Erica NormandinShibani S Mukerji
October 21, 2021

CODEHOP-Mediated PCR Improves HIV-1 Genotyping and Detection of Variants by MinION Sequencing.

Microbiology Spectrum
Horeyah Sarkhouh, Wassim Chehadeh
October 19, 2021

Prevalence and correlates of hypertension in HIV-positive adults from the Livingstone Central Hospital, Zambia.

The Pan African Medical Journal
Robert MusekwaSepiso Kenias Masenga
October 18, 2021
Open Access

Acquired HIV drug resistance and virologic monitoring in a HIV hyper-endemic setting in KwaZulu-Natal Province, South Africa.

AIDS Research and Therapy
Benjamin ChimukangaraKogieleum Naidoo
October 16, 2021

Single oral doses of MK-8507, a novel non-nucleoside reverse transcriptase inhibitor, suppress HIV-1 RNA for a week.

Journal of Acquired Immune Deficiency Syndromes : JAIDS
Dirk SchürmannWendy Ankrom
October 13, 2021

Perturbing HIV-1 ribosomal frameshifting frequency reveals a cis preference for Gag-Pol incorporation into assembling virions.

Journal of Virology
Bayleigh E BennerNathan M Sherer
October 13, 2021

Cooperative methylation of human tRNA3Lys at positions A58 and U54 drives the early and late steps of HIV-1 replication.

Nucleic Acids Research
Hiroyuki FukudaKazuhito Tomizawa
October 13, 2021
Open Access

Management of HIV-2 resistance to antiretroviral therapy in a HIV-1/HIV-2/HBV co-infected patient.

AIDS Research and Therapy
Margarida CardosoPerpétua Gomes
October 13, 2021

Therapeutic potential of indole derivatives as anti-HIV agents: A mini-review.

Current Topics in Medicinal Chemistry
Qingtai ChenZhi Xu

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