HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

March 7, 2020
Open Access

Preferential HLA-B27 Allorecognition Displayed by Multiple Cross-Reactive Antiviral CD8+ T Cell Receptors

Frontiers in Immunology
Louise C RowntreeNicole A Mifsud
February 28, 2020
Preprint
Open Access

Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

BioRxiv : the Preprint Server for Biology
Kristi KrebsJoão Fadista
August 1, 2020

Improved HLA-based prediction of coeliac disease identifies two novel genetic interactions

European Journal of Human Genetics : EJHG
Michael ErlichsterBenjamin Goudey
May 13, 2020
Open Access

The association between chronic spontaneous urticaria and HLA class I and class II antigen

Turkish Journal of Medical Sciences
Neslihan DoğanTaşkin Şentürk
March 25, 2020

Pharmacogenetics of antitumor necrosis factor therapy in severe sarcoidosis

Current Opinion in Pulmonary Medicine
Heleen CrommelinColine van Moorsel
April 25, 2020
Preprint
Open Access

In silico tools for accurate HLA and KIR inference from clinical sequencing data empower immunogenetics on individual-patient and population scales

BioRxiv : the Preprint Server for Biology
J. ChenChristian Hammer
June 4, 2020
Open Access

The Human Leukocyte Antigen Locus and Rheumatic Heart Disease Susceptibility in South Asians and Europeans

Scientific Reports
Kathryn AucklandTom Parks
February 19, 2020
Open Access

Genetic associations with clozapine-induced myocarditis in patients with schizophrenia

Translational Psychiatry
Paul LacazeMunir Pirmohamed
March 19, 2020
Open Access

GPU-Accelerated Discovery of Pathogen-Derived Molecular Mimics of a T-Cell Insulin Epitope

Frontiers in Immunology
Thomas WhalleyBarbara Szomolay
July 6, 2020
Open Access

Maternal respiratory infections in early pregnancy increases the risk of type 1 diabetes

Pediatric Diabetes
Malin BéltekyJohnny Ludvigsson
March 12, 2020
Open Access

The many faces of psoriatic arthritis: their genetic determinism

Rheumatology
Robert Winchester, Oliver FitzGerald
June 26, 2020

Immunogenetic protective factors in Genetic Generalized Epilepsy

Epilepsy Research
João ChavesBárbara Leal

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