HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

September 12, 2020
Case Report
Open Access

Multicentric Reticulohistiocytosis Exhibiting Positive HLA-B*07 and HLA-B*08: A Case Report

Elena RezușCiprian Rezuș
October 10, 2020
Open Access

Characterization of plasma lipidomics in adolescent subjects with increased risk for type 1 diabetes in the DiPiS cohort

Metabolomics : Official Journal of the Metabolomic Society
Agnes Andersson SvärdDiPiS Study Group
November 6, 2020

Association of MICA and HLA-B alleles with leprosy in two endemic populations in Brazil

International Journal of Immunogenetics
Luciana Ribeiro JarduliJeane Eliete Laguila Visentainer
December 2, 2020

A comprehensive overview on the genetics of Behçet's disease

International Reviews of Immunology
Mahdi MahmoudiFarhad Shahram
September 29, 2020

Human leukocyte antigen associations with renal function among ethnic minorities in the United Kingdom

HLA : Immune Response Genetics
Marcus LoweKay Poulton
October 6, 2020
Open Access

Analysis of Killer Cell Immunoglobulin-Like Receptor Genes and Their HLA Ligands in Inflammatory Bowel Diseases

Journal of Immunology Research
Fereshteh BeigmohammadiNima Rezaei
September 30, 2020
Open Access

HLA genetic polymorphisms and prognosis of patients with COVID-19

Medicina intensiva
L LorenteAnnex. Members of the BIOMEPOC group
September 23, 2020

Proteomic profile of preeclampsia in the first trimester of pregnancy

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Guillermo Jacobo-BacaLaura Elia Martínez-de-Villarreal
September 6, 2020
Open Access

Genome-wide Study Identifies Association between HLA-B∗ 55:01 and Self-Reported Penicillin Allergy

American Journal of Human Genetics
Kristi KrebsJoão Fadista
October 27, 2020
Open Access

A Myasthenia Gravis genomewide association study of three cohorts identifies Agrin as a novel risk locus.

MedRxiv : the Preprint Server for Health Sciences
A. TopaloudiPeristera Paschou
November 2, 2020
Comment / Editorial
Open Access

SARS-CoV-2, the autoimmune virus

Autoimmunity Reviews
Gilad Halpert, Yehuda Shoenfeld
October 11, 2020
Open Access

Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

Annals of the Rheumatic Diseases
Johanna K SandlingLars Rönnblom
January 14, 2021
Open Access

MiDAS - Meaningful Immunogenetic Data at Scale

BioRxiv : the Preprint Server for Biology
Maciej MigdalChristian Hammer
January 10, 2021
Open Access

Neuromyelitis optica is an HLA associated disease different from Multiple Sclerosis: a systematic review with meta-analysis

Scientific Reports
Marcos Papais AlvarengaRegina Maria Papais-Alvarenga
January 6, 2021

The JANUS of chronic inflammatory and autoimmune diseases onset during COVID-19 - A systematic review of the literature

Journal of Autoimmunity
Lucia NovelliCarlo Selmi
October 22, 2020
Open Access

Identification of a dysfunctional microglial population in human Alzheimer's disease cortex using novel single-cell histology image analysis

Acta Neuropathologica Communications
Molly E V SwansonMaurice A Curtis
September 29, 2020
Open Access

The Global Architecture Shaping the Heterogeneity and Tissue-Dependency of the MHC Class I Immunopeptidome is Evolutionarily Conserved

BioRxiv : the Preprint Server for Biology
P. KubiniokEtienne Caron
September 3, 2020
Open Access

Negative selection of human T cells recognizing a naturally-expressed tissue-restricted antigen in the human thymus

Journal of Translational Autoimmunity
Rachel MadleyMegan Sykes

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