Human Brain Cell: Single Cell Transcriptomes & DNA Methylomes

Single-cell analyses provide a better-resolved picture of complex biological processes and unmask heterogeneity found between cells. Here is the latest research employing single-cell transcriptomics and examining DNA methylomes in brain cells.

October 21, 2019
Review

The Molecular Basis of MeCP2 Function in the Brain

Journal of Molecular Biology
Rebekah Tillotson, Adrian Bird
August 16, 2019
Preprint
Open Access

Expression profiling of the mature C. elegans nervous system by single-cell RNA-Sequencing

BioRxiv : the Preprint Server for Biology
Seth R TaylorDavid M Miller
February 4, 2020
Preprint
Open Access

Cell Atlas of Aqueous Humor Outflow Pathways in Eyes of Humans and Four Model Species Provides Insights into Glaucoma Pathogenesis

BioRxiv : the Preprint Server for Biology
Tavé van ZylJoshua Richard Sanes
March 2, 2020
Preprint
Open Access

An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types

BioRxiv : the Preprint Server for Biology
Zizhen YaoEran A Mukamel
July 7, 2019
Preprint
Open Access

Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer's disease

BioRxiv : the Preprint Server for Biology
Samuel MorabitoVivek Swarup
August 12, 2019
Preprint
Open Access

Systematic search for schizophrenia pathways sensitive to perturbation by immune activation

BioRxiv : the Preprint Server for Biology
Xinping YangYanjun Li
November 26, 2019
Open Access

Intra- and intergenerational changes in the cortical DNA methylome in response to therapeutic intermittent hypoxia in mice

Physiological Genomics
Krystal Courtney D BelmonteJeffrey M Gidday
October 28, 2019
Preprint
Open Access

Northstar enables automatic classification of known and novel cell types from tumor samples

BioRxiv : the Preprint Server for Biology
Fabio ZaniniStephen R Quake
September 11, 2019

High-definition spatial transcriptomics for in situ tissue profiling

Nature Methods
Sanja VickovicPatrik L Ståhl
February 16, 2020

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

Cell
Joanna KaluckaPeter Carmeliet
November 7, 2019

An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome

Nature Structural & Molecular Biology
Chenxu ZhuBing Ren
August 27, 2019

A Derived Positional Mapping of Inhibitory Subtypes in the Somatosensory Cortex

Frontiers in Neuroanatomy
Daniel KellerHenry Markram

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