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Human Brain Cell: Single Cell Transcriptomes & DNA Methylomes

Human Brain Cell: Single Cell Transcriptomes & DNA Methylomes diagram by Wei-Chung Allen Lee et al, Wikimedia
Wei-Chung Allen Lee et al, Wikimedia

Single-cell analyses provide a better-resolved picture of complex biological processes and unmask heterogeneity found between cells. Here is the latest research employing single-cell transcriptomics and examining DNA methylomes in brain cells.

Top 20 most recent papers
Proceedings of the National Academy of Sciences of the United States of America

Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain

Proceedings of the National Academy of Sciences of the United States of AmericaNovember 28, 2019
Devon S SvobodaRudolf Jaenisch
33
1
Cell

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

CellFebruary 16, 2020
Joanna KaluckaPeter Carmeliet
166
2
2
Nature Genetics

Stalled developmental programs at the root of pediatric brain tumors

Nature GeneticsNovember 27, 2019
Selin JessaClaudia L Kleinman
91
6
1
bioRxiv

Heterogeneity of Neuroepithelial Cells and Radial Glia

bioRxivMarch 7, 2020
Ugomma C. EzeArnold R. Kriegstein
44
Nature Neuroscience

Single-cell analysis of olfactory neurogenesis and differentiation in adult humans

Nature NeuroscienceFebruary 19, 2020
Michael A DuranteBradley J Goldstein
266
3
bioRxiv

Single cell atlas of trisomy 21 cerebral cortex

bioRxivJanuary 2, 2020
Jingxuan ZhangXun Xu
2
210
1
194
7
Cell

Modeling the Evolution of Human Brain Development Using Organoids

CellNovember 29, 2019
Sydney Keaton MuchnikNenad Sestan
36
2
Clinical Epigenetics

Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood

Clinical EpigeneticsNovember 29, 2019
Roy LardenoijeDaniël L A van den Hove
4
1

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