Human Brain Cell: Single Cell Transcriptomes & DNA Methylomes

Single-cell analyses provide a better-resolved picture of complex biological processes and unmask heterogeneity found between cells. Here is the latest research employing single-cell transcriptomics and examining DNA methylomes in brain cells.

June 13, 2020

Human CNS barrier-forming organoids with cerebrospinal fluid production

Science
Laura PellegriniMadeline A Lancaster
July 3, 2020
Preprint
Open Access

Molecular architecture of the developing mouse brain

BioRxiv : the Preprint Server for Biology
G. La MannoSten Linnarsson
February 4, 2020
Preprint
Open Access

Cell Atlas of Aqueous Humor Outflow Pathways in Eyes of Humans and Four Model Species Provides Insights into Glaucoma Pathogenesis

BioRxiv : the Preprint Server for Biology
Tavé van ZylJoshua Richard Sanes
February 13, 2020
Open Access

Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain

Cell Reports
Yoshiaki TanakaIn-Hyun Park
January 17, 2020
Open Access

Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation

ELife
Ankit JambusariaJalees Rehman
July 16, 2020
Preprint
Open Access

Multi-modal single cell analysis reveals brain immune landscape plasticity during aging and gut microbiota dysbiosis

BioRxiv : the Preprint Server for Biology
S. M. GolombSiyuan Zhang
August 14, 2020
Open Access

High throughput error corrected Nanopore single cell transcriptome sequencing

Nature Communications
Kevin LebrigandRainer Waldmann
January 31, 2020
Open Access

Cell stress in cortical organoids impairs molecular subtype specification

Nature
Aparna BhaduriArnold R Kriegstein
March 2, 2020
Preprint
Open Access

An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types

BioRxiv : the Preprint Server for Biology
Zizhen YaoHongkui Zeng
August 4, 2020

Cell death and survival pathways in Alzheimer's disease: an integrative hypothesis testing approach utilizing -omic data sets

Neurobiology of Aging
Danielle L BrokawPaul D Coleman
November 26, 2019
Open Access

Intra- and intergenerational changes in the cortical DNA methylome in response to therapeutic intermittent hypoxia in mice

Physiological Genomics
Krystal Courtney D BelmonteJeffrey M Gidday
July 4, 2020

Paradoxical whole genome DNA methylation dynamics of 5'aza-deoxycytidine in chronic low-dose exposure in mice

Epigenetics : Official Journal of the DNA Methylation Society
Mathia ColwellChristopher Faulk
October 28, 2019
Preprint
Open Access

Northstar enables automatic classification of known and novel cell types from tumor samples

BioRxiv : the Preprint Server for Biology
Fabio ZaniniStephen R Quake
February 16, 2020
Open Access

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

Cell
Joanna KaluckaPeter Carmeliet
November 7, 2019

An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome

Nature Structural & Molecular Biology
Chenxu ZhuBing Ren
August 18, 2020
Open Access

Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer's disease

Human Molecular Genetics
Samuel MorabitoVivek Swarup

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