Single Brain Cell Transcriptomes & Methylomes

Single-cell analyses provide a better-resolved picture of complex biological processes and unmask heterogeneity found between cells. Here is the latest research employing single-cell transcriptomics and examining DNA methylomes in brain cells.

February 28, 2021
Review

Stress and Its Impact on the Transcriptome.

Biological Psychiatry
Matthew J GirgentiSamuel S Newton
February 27, 2021
Review

Formation and integration of new neurons in the adult hippocampus.

Nature Reviews. Neuroscience
Annina Denoth-Lippuner, Sebastian Jessberger
February 25, 2021

ESCO: single cell expression simulation incorporating gene co-expression.

Bioinformatics
Jinjin TianKathryn Roeder
February 24, 2021
Preprint
Open Access

The developing mouse coronal suture at single-cell resolution

BioRxiv : the Preprint Server for Biology
D. T. FarmerStephen RF Twigg
February 24, 2021

Single-Cell RNA Sequencing Analysis of the Drosophila Larval Ventral Cord.

Current Protocols
Tho Huu NguyenMihaela Serpe
February 21, 2021
Open Access

Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages.

Nature Communications
Natalia OchockaBozena Kaminska
February 20, 2021

White matter aging drives microglial diversity.

Neuron
Shima SafaiyanMikael Simons
February 18, 2021

SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females.

American Journal of Human Genetics
Francesca Clementina RadioMarco Tartaglia
February 17, 2021

Joint profiling of histone modifications and transcriptome in single cells from mouse brain.

Nature Methods
Chenxu ZhuBing Ren
February 15, 2021

Hippocampal transcriptome deconvolution reveals differences in cell architecture of not demented elderly subjects underwent late-life physical activity.

Journal of Chemical Neuroanatomy
Cristina SanfilippoMichelino Di Rosa
February 12, 2021
Preprint
Open Access

A robust method of nuclei isolation for single-cell RNA sequencing of solid tissues from the plant genus Populus

BioRxiv : the Preprint Server for Biology
D. CondeMatias Kirst
February 12, 2021
Open Access

Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi.

Endocrinology
Melody Allensworth-JamesAngus M MacNicol
February 9, 2021
Review
Open Access

Genomic and Epigenetic Advances in Focal Cortical Dysplasia Types I and II: A Scoping Review.

Frontiers in Neuroscience
Joana Jesus-RibeiroJoana Barbosa Melo
February 9, 2021
Open Access

Novel Targets of SARS-CoV-2 Spike Protein in Human Fetal Brain Development Suggest Early Pregnancy Vulnerability.

Frontiers in Neuroscience
Parul VarmaJenny Hsieh
February 8, 2021
Preprint
Open Access

Cell Type Hierarchy Reconstruction via Reconciliation of Multi-resolution Cluster Tree

BioRxiv : the Preprint Server for Biology
M. PengKathryn Roeder
February 6, 2021
Open Access

SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes.

Nucleic Acids Research
Marc Elosua-BayesHolger Heyn
February 6, 2021
Open Access

Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.

Proceedings of the National Academy of Sciences of the United States of America
Tyler M LuRaphaël Lis

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