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Huntington Disease

Huntington Disease diagram by Blamb, Shutterstock
Blamb, Shutterstock

Huntington disease is a hereditary neurodegenerative disease characterized by poor coordination and involuntary body movements. Discover the latest research on Huntington disease here.

Top 20 most recent papers
Cell Reports

Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival

Cell ReportsJanuary 23, 2020
Caley J BurrusCagla Eroglu
60
3
bioRxiv

GAPDH controls extracellular vesicle biogenesis and enhances therapeutic potential of EVs in silencing the Huntingtin gene in mice via siRNA delivery

bioRxivJanuary 9, 2020
Ghulam Hassan DarMatthew J. A. Wood
4
bioRxiv

cGAS, a DNA Sensor, Promotes Inflammatory Responses in Huntington Disease

bioRxivJanuary 9, 2020
Manish SharmaSrinivasa Subramaniam
5
Cells

Mitophagy in Alzheimer's Disease and Other Age-Related Neurodegenerative Diseases

CellsJanuary 16, 2020
Qian Cai, Yu Young Jeong
2
1
Rehabilitation Psychology

Understanding domains that influence perceived stigma in individuals with Huntington disease

Rehabilitation PsychologyJanuary 22, 2020
Nicholas R BoileauNoelle E Carlozzi
2
Movement Disorders : Official Journal of the Movement Disorder Society

Early-motor phenotype relates to neuropsychiatric and cognitive disorders in huntington's disease

Movement Disorders : Official Journal of the Movement Disorder SocietyJanuary 11, 2020
Parunyou JulayanontNikolaus R McFarland
5
1
Journal of Pharmacological and Toxicological Methods

Pharmacological investigation of biochemical and behavioral effects resembling Huntington's disease utilizing selective calcium and calmodulin dependent phosphodiesterase inhibitor

Journal of Pharmacological and Toxicological MethodsJanuary 23, 2020
Ravinesh Mishra
European Journal of Pharmacology

Neuroprotective effects of novel nitrones: In vitro and in silico studies

European Journal of PharmacologyJanuary 21, 2020
Saira CancelaAlicia Merlino
1
Cell Death & Disease

Interferon mediated neuroinflammation in polyglutamine disease is not caused by RNA toxicity

Cell Death & DiseaseJanuary 11, 2020
Aksheev BhambriBeena Pillai
1
1
Protein and Peptide Letters

The Renin-Angiotensin System in Huntington's disease: Villain or hero?

Protein and Peptide LettersJanuary 15, 2020
Thatiane C G MachadoLucas M Kangussu
2
1
bioRxiv

Intra-striatal AAV2.retro administration leads to extensive retrograde transport in the rhesus macaque brain: implications for disease modeling and therapeutic development

bioRxivJanuary 18, 2020
Alison R WeissJodi L McBride
29
Psychiatry and Clinical Neurosciences

Effectiveness of Brexpiprazole in the Treatment in a Patient with Huntington's Disease

Psychiatry and Clinical NeurosciencesJanuary 14, 2020
Yu MimuraMasaru Mimura
2
The Journal of Physical Chemistry. a

Quantum Dynamics Study of the C(1 D)+HD Reaction on the ã1A' and b̃1A" Potential Energy Surfaces

The Journal of Physical Chemistry. aJanuary 21, 2020
Yanan WuWensheng Bian
Brain Sciences

Therapeutic Advances for Huntington's Disease

Brain SciencesJanuary 17, 2020
Ashok KumarJong-Joo Kim
3
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Altered Cortical Morphometry in Pre-manifest Huntington's Disease: Cross-sectional Data from the IMAGE-HD Study

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology SocietyJanuary 18, 2020
Rosita ShishegarNellie Georgiou-Karistianis
Psychosomatics

Neuroendocrine Disturbances in Neurodegenerative Disorders: A Scoping Review

PsychosomaticsJanuary 11, 2020
Amy Newhouse, Zeina Chemali
1
CNS Drugs

Recent Advances in the Treatment of Huntington's Disease: Targeting DNA and RNA

CNS DrugsJanuary 15, 2020
Kathleen M Shannon
3
1
Frontiers in Neurology

Therapeutic Applications of Cysteamine and Cystamine in Neurodegenerative and Neuropsychiatric Diseases

Frontiers in NeurologyJanuary 11, 2020
Bindu D Paul, Solomon H Snyder
8
1
Nature Immunology

Homeostatic regulation of STING protein at the resting state by stabilizer TOLLIP

Nature ImmunologyJanuary 15, 2020
Vladislav PokatayevNan Yan
39
Communications Biology

A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites

Communications BiologyJanuary 12, 2020
Shaowei ZhangNigel S Scrutton

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