Huntington’s Disease: Genetics

Huntington’s disease (HD) is a hereditary neurodegenerative disease caused by mutations in the HTT gene, which encodes the huntingtin protein. HD is characterized by poor coordination and involuntary body movements. Here is the latest research on Huntington's disease genetics.

April 14, 2021
Open Access

FAN1 nuclease activity affects CAG expansion and age at onset of Huntington's disease

BioRxiv : the Preprint Server for Biology
B. H. McAllisterThomas H Massey
April 14, 2021

Modulation of Huntington's disease in Drosophila.

CNS & Neurological Disorders Drug Targets
Iqra Subhan, Yasir Hasan Siddique
April 5, 2021

Converging evidence in support of omega-3 polyunsaturated fatty acids as a potential therapy for Huntington's disease symptoms.

Reviews in the Neurosciences
Owen M Vega, Carlos Cepeda
April 4, 2021
Open Access

A Systematic Review of Genetic Polymorphisms Associated with Binge Eating Disorder.

Lucia ManfrediDavid Conversi
April 3, 2021
Open Access

An Australian Neuro-Palliative perspective on Huntington's disease: a case report.

BMC Palliative Care
Rajvi ShahChristopher Grossman
April 1, 2021

Geographic differences in the incidence of Huntington's disease in Sardinia, Italy.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Antonella MuroniGiovanni Defazio
March 30, 2021
Open Access

Neurodegenerative Disease and the NLRP3 Inflammasome.

Frontiers in Pharmacology
Jonathan A HolbrookMichael F McDermott
March 27, 2021
Open Access

Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signalled to DNA damage by Ataxia Telangiectasia Mutated kinase.

Human Molecular Genetics
Celeste SuartRay Truant
March 27, 2021
Open Access

Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model.

Journal of Enzyme Inhibition and Medicinal Chemistry
Yu Jin HwangSun-Joon Min
March 27, 2021

Role of older generations in the family's adjustment to Huntington disease.

Journal of Community Genetics
Carla Roma OliveiraLiliana Sousa
March 26, 2021

Population genetic variation of SLC6A4 gene, associated with neurophysiological development.

Journal of Genetics
Shyamala H HandeRanajit Das
March 23, 2021
Open Access

Ablation of kynurenine 3-monooxygenase rescues plasma inflammatory cytokine levels in the R6/2 mouse model of Huntington's disease.

Scientific Reports
Marie Katrin BondulichGillian P Bates
March 22, 2021
Open Access

Tissue Microbiome Associated With Human Diseases by Whole Transcriptome Sequencing and 16S Metagenomics.

Frontiers in Genetics
Rana Salihoğlu, Tuğba Önal-Süzek
March 19, 2021
Open Access

On the hunt for a cure: A guide to Huntington disease.

JAAPA : Official Journal of the American Academy of Physician Assistants
Jennifer de la Cruz, Joseph Hwang
March 17, 2021

Predictors of Caregiver Burden in Huntington's Disease.

Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists
Danielle C Hergert, Cynthia R Cimino
March 14, 2021
Open Access

Neurodegeneration and epigenetics: A review.

Neurología : publicación oficial de la Sociedad Española de Neurología
P Ghosh, A Saadat
March 14, 2021
Open Access

Transcriptional profiling reveals the transcription factor networks regulating the survival of striatal neurons.

Cell Death & Disease
Lin YangZhuangzhi Zhang

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