Huntington's Disease

Huntington's disease is a hereditary neurodegenerative disease characterized by poor coordination and involuntary body movements. Discover the latest research on Huntington's disease here.

January 17, 2021
Open Access

Inhibition of mitochondrial complex II in neuronal cells triggers unique pathways culminating in autophagy with implications for neurodegeneration

Scientific Reports
Sathyanarayanan RanganayakiMuchukunte Mukunda Srinivas Bharath
January 7, 2021
Preprint
Open Access

A meta-analysis of transcriptomic profiles from Huntington's disease patients substantiates the pathophysiological role of CDC42, NFY, DLX1 and PRMT3

BioRxiv : the Preprint Server for Biology
Manuel Seefelder, S. Kochanek
January 8, 2021
Review
Open Access

An update on the role of miR-124 in the pathogenesis of human disorders

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Soudeh Ghafouri-FardMohammad Taheri
January 4, 2021
Review

Neuroprotection through G-CSF: recent advances and future viewpoints

Pharmacological Reports : PR
Vikrant RahiPuneet Kumar
January 10, 2021
Open Access

Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats

Nature Communications
Tianyu HuSteven W Magennis
January 5, 2021

Bioactive Phytocompounds: Anti-amyloidogenic Effects Against Hen Egg-White Lysozyme Aggregation

The Protein Journal
Suman Chowdhury, Suresh Kumar
January 13, 2021

Mutations causing Lopes-Maciel-Rodan Syndrome are huntingtin hypomorphs

Human Molecular Genetics
Roy JungIhn Sik Seong
January 13, 2021
Open Access

Regulation of neuronal bioenergetics as a therapeutic strategy in neurodegenerative diseases

Neural Regeneration Research
Isaac G OnyangoGorazd B Stokin
January 12, 2021
Review
Open Access

Dysregulation of Neuronal Calcium Signaling via Store-Operated Channels in Huntington's Disease

Frontiers in Cell and Developmental Biology
Magdalena Czeredys
January 10, 2021

Fibroblast Growth Factor 9 Stimulates Neuronal Length Through NF-kB Signaling in Striatal Cell Huntington's Disease Models

Molecular Neurobiology
Issa Olakunle YusufShang-Hsun Yang
January 14, 2021
Preprint
Open Access

Genetic epidemiological characteristics of a Hungarian subpopulation of patients with Huntington’s Disease

ResearchSquare
Katalin DespotovPeter Klivenyi
January 10, 2021
Open Access

Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse model

Scientific Reports
M J Vijay KumarJames P Clement
January 8, 2021
Preprint
Open Access

Dysregulation of the basal ganglia indirect pathway prior to cell loss in the Q175 mouse model of Huntington's disease

BioRxiv : the Preprint Server for Biology
J. CallahanMark D Bevan
January 8, 2021

Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease

Journal of Controlled Release : Official Journal of the Controlled Release Society
Giulia BiroliniElena Cattaneo
January 7, 2021
Review
Open Access

Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid

International Journal of Molecular Sciences
Fanni TóthLászló Vécsei
January 15, 2021

Discovery of the First Druggable GPR52 Antagonist to Treat Huntington's Disease

Journal of Medicinal Chemistry
Hidetoshi Komatsu
January 3, 2021
Preprint
Open Access

Distribution of Huntington's disease Haplogroups in Indian population

BioRxiv : the Preprint Server for Biology
S. D. VMeera Purushottam

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