Hutchinson-Gilford Progeria Syndrome

Hutchinson-Gilford progeria syndrome is a very rare premature aging disorder that affects children, clinically mimicking physiological aging at a young age. The disease incidence is estimated at 1 in 18 million. Discover the latest research on Hutchinson-Gilford progeria syndrome here.

January 15, 2022
Open Access

Mechanisms of A-type lamin targeting to nuclear ruptures are disrupted in LMNA- and BANF1- associated progerias

BioRxiv : the Preprint Server for Biology
R. M. Sears, Kyle J Roux
January 14, 2022
Case Report

Novel Compound Heterozygous Variants in the CDC6 Gene in a Russian Patient with Meier-Gorlin Syndrome.

The Application of Clinical Genetics
Viktoriia ZabnenkovaOxana Ryzhkova
January 14, 2022

Cardiovascular manifestations of Hutchinson-Gilford progeria syndrome.

Cardiology in the Young
Andreia PalmaAntónio Pires
January 13, 2022

Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria.

Christina ManakanatasSelma Osmanagic-Myers
January 10, 2022

Progerin-Expressing Endothelial Cells are Unable to Adapt to Shear Stress.

Biophysical Journal
B. E. DanielssonDaniel E Conway
December 19, 2021
Open Access

Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford Progeria Syndrome

BioRxiv : the Preprint Server for Biology
S.-I. MurtadaJay D Humphrey
November 28, 2021
Case Report
Open Access

Efficacy of Cord Blood Cell Therapy for Hutchinson-Gilford Progeria Syndrome-A Case Report.

International Journal of Molecular Sciences
Mi Ri SuhMinYoung Kim
November 12, 2021
Open Access

Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice

BioRxiv : the Preprint Server for Biology
Y. WangHoward J. Worman
November 5, 2021

More Than Skin Deep - the Effects of Ultraviolet Radiation on Cathepsin K and Progerin Expression in Cultured Dermal Fibroblasts.

Clinical, Cosmetic and Investigational Dermatology
Igor Aleksander BednarskiAleksandra Lesiak
November 5, 2021
Open Access

Targeting SerpinE1 reverses cellular features of Hutchinson-Gilford progeria syndrome

BioRxiv : the Preprint Server for Biology
G. CatarinellaLucia Latella
October 26, 2021

Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome.

Amanda Sánchez-LópezVicente Andrés
October 11, 2021

Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model.

Gustavo Satoru KajitaniJames Robert Mitchell
October 5, 2021

Rhinoplasty on Hutchinson-Gilford Progeria Syndrome Patient.

Aesthetic Plastic Surgery
Mauro BaronePaolo Persichetti
October 4, 2021

Electromagnetized gold nanoparticles improve neurogenesis and cognition in the aged brain.

Yujung ChangJongpil Kim
September 14, 2021
Open Access

Activation of endoplasmic reticulum stress via clustering of inner nuclear membrane proteins

BioRxiv : the Preprint Server for Biology
S. VidakTom Misteli
September 14, 2021

Atherosclerosis and Cardiovascular Diseases in Progeroid Syndromes.

Journal of Atherosclerosis and Thrombosis
Hisaya Kato, Yoshiro Maezawa
September 6, 2021

[Hutchinson-Gilford progeria syndrome].

Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics
September 2, 2021
Open Access

Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome.

ACS Central Science
Beatriz Marcos-RamiroSilvia Ortega-Gutiérrez

Sign up to follow this feed and discover related papers.

Related Feeds

22q11 Deletion Syndrome

22q11.2 deletion syndrome, also known as DiGeorge syndrome, is a congenital disorder caused by a partial deletion of chromosome 22. Symptoms include heart defects, poor immune system function, a cleft palate, complications related to low levels of calcium in the blood, and delayed development. Discover the latest research on this disease here.

4H Leukodystrophy

4H Leukodystrophy involves hypomyelination with hypogonadotropic hypogonadism and hypodontia. It is also known as POLR-3 Related Leukodystrophy. 4H syndrome symptoms include delayed or abnormal puberty, issues with central nervous system signal transmission, abnormal development of teeth, and symptoms tend to progressively get worse over time. Here is the latest research on this disease.

AAV-based Gene Therapy

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

ALS: Genetics

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ATG proteins

The discovery of autophagy-related ('ATG') proteins in the 1990s greatly advanced the mechanistic understanding of autophagy and clarified the fact that autophagy serves important roles in various biological processes.

Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.

Adult Polyglucosan Body Disease

Adult polyglucosan body disease (APBD) is a rare autosomal recessive disease characterized by defects in the glycogen brancher enzyme 1 (GBE1) gene. Discover the latest research on APBD here.

Aging & Diabetes

This feed focuses on the role of the aging process on developing diabetes.

Aging-Associated Metabolic Disorders

Age is associated with many metabolic disorders including cardiovascular diseases, type 2 diabetes, stroke and heart disease. The mediators in aging process have been suggested to play a part in the cellular processes responsible for these metabolic disorders. Here is the latest research on aging-associated metabolic disorders.

© 2022 Meta ULC. All rights reserved