Hutchinson-Gilford Progeria Syndrome

Hutchinson-Gilford progeria syndrome is a very rare premature aging disorder that affects children, clinically mimicking physiological aging at a young age. The disease incidence is estimated at 1 in 18 million. Discover the latest research on Hutchinson-Gilford progeria syndrome here.

January 15, 2022
Preprint
Open Access

Mechanisms of A-type lamin targeting to nuclear ruptures are disrupted in LMNA- and BANF1- associated progerias

BioRxiv : the Preprint Server for Biology
R. M. Sears, Kyle J Roux
January 14, 2022
Case Report

Novel Compound Heterozygous Variants in the CDC6 Gene in a Russian Patient with Meier-Gorlin Syndrome.

The Application of Clinical Genetics
Viktoriia ZabnenkovaOxana Ryzhkova
January 14, 2022

Cardiovascular manifestations of Hutchinson-Gilford progeria syndrome.

Cardiology in the Young
Andreia PalmaAntónio Pires
January 13, 2022

Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria.

Aging
Christina ManakanatasSelma Osmanagic-Myers
January 10, 2022

Progerin-Expressing Endothelial Cells are Unable to Adapt to Shear Stress.

Biophysical Journal
B. E. DanielssonDaniel E Conway
December 19, 2021
Preprint
Open Access

Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford Progeria Syndrome

BioRxiv : the Preprint Server for Biology
S.-I. MurtadaJay D Humphrey
November 28, 2021
Case Report
Open Access

Efficacy of Cord Blood Cell Therapy for Hutchinson-Gilford Progeria Syndrome-A Case Report.

International Journal of Molecular Sciences
Mi Ri SuhMinYoung Kim
November 12, 2021
Preprint
Open Access

Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice

BioRxiv : the Preprint Server for Biology
Y. WangHoward J. Worman
November 5, 2021

More Than Skin Deep - the Effects of Ultraviolet Radiation on Cathepsin K and Progerin Expression in Cultured Dermal Fibroblasts.

Clinical, Cosmetic and Investigational Dermatology
Igor Aleksander BednarskiAleksandra Lesiak
November 5, 2021
Preprint
Open Access

Targeting SerpinE1 reverses cellular features of Hutchinson-Gilford progeria syndrome

BioRxiv : the Preprint Server for Biology
G. CatarinellaLucia Latella
October 26, 2021

Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome.

Circulation
Amanda Sánchez-LópezVicente Andrés
October 11, 2021

Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model.

Aging
Gustavo Satoru KajitaniJames Robert Mitchell
October 5, 2021

Rhinoplasty on Hutchinson-Gilford Progeria Syndrome Patient.

Aesthetic Plastic Surgery
Mauro BaronePaolo Persichetti
October 4, 2021

Electromagnetized gold nanoparticles improve neurogenesis and cognition in the aged brain.

Biomaterials
Yujung ChangJongpil Kim
September 14, 2021
Preprint
Open Access

Activation of endoplasmic reticulum stress via clustering of inner nuclear membrane proteins

BioRxiv : the Preprint Server for Biology
S. VidakTom Misteli
September 14, 2021

Atherosclerosis and Cardiovascular Diseases in Progeroid Syndromes.

Journal of Atherosclerosis and Thrombosis
Hisaya Kato, Yoshiro Maezawa
September 6, 2021

[Hutchinson-Gilford progeria syndrome].

Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics
September 2, 2021
Open Access

Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome.

ACS Central Science
Beatriz Marcos-RamiroSilvia Ortega-Gutiérrez

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