IL-6/JAK/STAT3 Pathway

The IL-6/JAK/STAT3 pathway is overactive in several cancer types. The increased activity of this pathway enhances tumor growth proliferation, survival and increases metastases of cancer cells. The target of the pathway to inhibit tumor growth is currently being explored. Here is the latest research on the IL-6/JAK/STAT3 pathway in cancer.

January 21, 2022
Open Access

Proteomimetics of Natural Regulators of JAK-STAT Pathway: Novel Therapeutic Perspectives.

Frontiers in Molecular Biosciences
Sara La MannaDaniela Marasco
January 21, 2022
Open Access

FGFC1 Exhibits Anti-Cancer Activity via Inhibiting NF-κB Signaling Pathway in EGFR-Mutant NSCLC Cells.

Marine Drugs
Jingwen FengWenhui Wu
January 19, 2022

The Biomarkers for Predicting Viral HepatitisAssociated Hepatocellular Carcinoma.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology
Qing YangCunliang Deng
January 17, 2022

Glioma-targeted delivery of exosome-encapsulated antisense oligonucleotides using neural stem cells.

Molecular Therapy. Nucleic Acids
Tomasz AdamusMarcin Kortylewski
January 17, 2022

Antiulcer activity of proanthocyanidins is mediated via suppression of oxidative, inflammatory, and apoptotic machineries.

Journal of Food Biochemistry
Maha S LokmanRami B Kassab
January 17, 2022
Open Access

SHC4 promotes tumor proliferation and metastasis by activating STAT3 signaling in hepatocellular carcinoma.

Cancer Cell International
Xin ZhangKeshuai Dong
January 16, 2022

Renal consequences of the novel coronavirus disease 2019 (COVID-19) and hydrogen sulfide as a potential therapy.

Nitric Oxide : Biology and Chemistry
George J DugbarteyAlp Sener
January 15, 2022

Inhibition of GP130/STAT3 and EMT by combined bazedoxifene and paclitaxel treatment in ovarian cancer.

Oncology Reports
Sun-Ae ParkTae-Hwe Heo

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