Immune System: Tissues & Aging

Mapping the human immune system spatially, within and between tissues, will provide the basis for studying mechanisms of tissue residency and the effects of aging. This feed follos new studies profiling the immune system, including at different developmental stages.

January 16, 2022

Decoding the role of macrophages in periodontitis and type 2 diabetes using single-cell RNA-sequencing.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Panagiota AgrafiotiFatemeh Momen-Heravi
January 16, 2022

Lidocaine Ameliorates Psoriasis by Obstructing Pathogenic CGRP Signaling-Mediated Sensory Neuron-Dendritic Cell Communication.

The Journal of Investigative Dermatology
Qianqian YinHonglin Wang
January 16, 2022

Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia.

Cell Death and Differentiation
Florence VallelianDominik J Schaer
January 16, 2022

Reproducibility of 10x Genomics single cell RNA sequencing method in the immune cell environment.

Journal of Immunological Methods
Gloria KrausEzio Bonifacio
January 16, 2022
Review

Present and future of microglial pharmacology.

Trends in Pharmacological Sciences
Eva ŠimončičováMarie-Ève Tremblay
January 15, 2022
Open Access

Human immunocompetent choroid-on-chip: a novel tool for studying ocular effects of biological drugs.

Communications Biology
Madalena CiprianoPeter Loskill
January 15, 2022

Cell2location maps fine-grained cell types in spatial transcriptomics.

Nature Biotechnology
Vitalii KleshchevnikovOmer Ali Bayraktar
January 15, 2022

T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma.

Nature Medicine
Alexander X LozanoAaron M Newman
January 15, 2022
Open Access

A Single-Cell Transcriptome Profiling of Anterior Kidney Leukocytes From Nile Tilapia (Oreochromis niloticus).

Frontiers in Immunology
Liting WuJianmin Ye
January 14, 2022

MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8+ T Cell Responses.

The Journal of Immunology : Official Journal of the American Association of Immunologists
Jennifer L HopePeter D Katsikis
January 14, 2022

Contribution of Transcriptome to Elucidate the Biology of Plasmodium spp.

Current Topics in Medicinal Chemistry
Kleber Simônio ParreiraR S Garcia
January 13, 2022
Review

Single-cell profiling of tumour evolution in multiple myeloma - opportunities for precision medicine.

Nature Reviews. Clinical Oncology
Ankit K DuttaIrene M Ghobrial
January 13, 2022

Distinct properties of adipose stem cell subpopulations determine fat depot-specific characteristics.

Cell Metabolism
Hahn NahmgoongJae Bum Kim
January 12, 2022
Preprint
Open Access

Single-nucleus RNA-seq of normal-appearing brain regions in relapsing-remitting vs. secondary progressive multiple sclerosis

BioRxiv : the Preprint Server for Biology
Yasuyuki KiharaJ. Chun
January 12, 2022

NKG7 Is Required for Optimal Antitumor T-cell Immunity.

Cancer Immunology Research
Xian-Yang LiChristian R Engwerda

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