Immunogenetics of CNS Tumors

Central nervous system (CNS) tumors have a unique tumor immune microenvironment, where immune cells can play a role in disease progression and resistance to therapy. Studying the immunogenetics of these cells can uncover mechanisms underlying their role in CNS tumors. Here is the latest research.

December 7, 2018
Open Access

Pseudoprogression: fact or wishful thinking in neuro-oncology?

The Lancet Oncology
David A Reardon, Michael Weller
July 22, 2020
Open Access

In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases

Journal for Immunotherapy of Cancer
Paul A ClarkZachary S Morris
February 15, 2020
Open Access

Implications of New Understandings of Gliomas in Children and Adults with NF1: Report of a Consensus Conference

Neuro-oncology
Roger J PackerDavid H Gutmann
February 29, 2020
Review

Glucocorticoids and immune checkpoint inhibitors in glioblastoma

Journal of Neuro-oncology
William J Kelly, Mark R Gilbert
July 20, 2019

Tisagenlecleucel CAR T-cell therapy in secondary CNS lymphoma

Blood
Matthew J FrigaultMarcela V Maus
September 14, 2019
Comment / Editorial
Open Access

The CNS can be a safe space for CARs

Blood
Carlos Almeida Ramos
August 1, 2020
Open Access

Small Extracellular Vesicles Isolated from Serum May Serve as Signal-Enhancers for the Monitoring of CNS Tumors

International Journal of Molecular Sciences
Gabriella DobraKrisztina Buzas
June 22, 2020
Review

Update on Pediatric Brain Tumors: the Molecular Era and Neuro-immunologic Beginnings

Current Neurology and Neuroscience Reports
Elizabeth S Duke, Roger J Packer
July 4, 2020
Review

Advances in Molecular Classification and Therapeutic Opportunities in Meningiomas

Current Oncology Reports
Christine Cordova, Sylvia C Kurz
December 8, 2019

Characterisation of tumour microenvironment and immune checkpoints in primary central nervous system diffuse large B cell lymphomas

Virchows Archiv : an International Journal of Pathology
Melissa AlameVanessa Szablewski
April 27, 2020

In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy

Cancer Immunology, Immunotherapy : CII
Lukas MarcelisThomas Tousseyn
July 12, 2019
Review

Primary central nervous system lymphoma: Novel precision therapies

Critical Reviews in Oncology/hematology
Patrizia MondelloFrancesco Bertoni
February 11, 2020
Review
Open Access

Tumor antigens in glioma

Seminars in Immunology
Takahide NejoHideho Okada
March 1, 2020
Review

Blood-brain barrier opening with low intensity pulsed ultrasound for immune modulation and immune therapeutic delivery to CNS tumors

Journal of Neuro-oncology
Kevin BeccariaAmy B Heimberger
March 29, 2019
Review

Central Nervous System Involvement of Natural Killer and T Cell Neoplasms

Current Oncology Reports
Ashley E Aaroe, Kathryn S Nevel

Sign up to follow this feed and discover related papers.

Related Feeds

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Cognitive Decline: Environmental And Genetic Factors

This feed focuses on the role of environmental and genetic factors including environmental policies, disease susceptibility, and socioeconomic status on cognitive decline. Here is the latest research.

Epigenetic Changes in Pain

Targeted epigenetic interventions provide the tools to prevent nociceptive sensitization, mood-related symptoms, and other adaptations that occur in response to injury or inflammation, which will facilitate pain management and improve treatment efficacy in many chronic pain conditions. Here is the latest research on the epigenetics changes in pain.

Epigenetic Regulation of Microglia Functions

Microglial cells are instrumental in the maintenance of homeostasis in the CNS and can contribute to neurodegenerative disorders. Epigenetic mechanisms and transcriptional regulation may be potential therapeutic targets for their activation or suppression. Discover the latest research on epigenetic regulation of microglial functions here.

Gene-Environment Interaction & Behaviour

Gene-environment interaction is when two different genotypes respond to environmental variation in different ways.Genes and environment interact to form an individual's personality. Abnormal or extreme behaviour could thus be explained by hereditary factors in combination with poor environmental conditions.

Genetic Influences on Brain Development

The genetic landscape of an individual can have drastic effects on brain development and brain developmental disorders. Discover the latest research here.

Genetic Networks Underlying Habituation

Habituation, the gradual waning of an evoked behavioral response with repeated stimulation, is a basic and universal form of learning. This feed explores the genetic networks that are involved in the occurence of habituation.

Genetic Screens in iPSC-Derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Genetics of Pain

Subtle changes in DNA could partly explain the variation in individual differences in pain. There is growing evidence that a number of genes play a critical role in determining pain sensitivity, pain reporting and susceptibility to developing chronic pain and their response to surgical outcomes primarily, pain.

Neurogenetic Disorders

Neurogenetic disorders are caused by a defect in one or more genes affecting the differentiation and function of the neuroectoderm and its derivatives. Here is the latest research on neurogenetic disorders

© 2020 Meta ULC. All rights reserved
/feed-previews/immunogenetics-of-cns-tumors/e9c69a88-0706-49c7-a424-be8017cec898