Feed Preview

Fast Growing

Immunogenetics of CNS Tumors

Immunogenetics of CNS Tumors diagram by O_Akira, Shutterstock
O_Akira, Shutterstock

Central nervous system (CNS) tumors have a unique tumor immune microenvironment, where immune cells can play a role in disease progression and resistance to therapy. Studying the immunogenetics of these cells can uncover mechanisms underlying their role in CNS tumors. Here is the latest research.

Top 20 most recent papers
Ecancermedicalscience

Successful osimertinib rechallenge following drug-induced pneumonitis after previous anti-PDL1 exposure

EcancermedicalscienceJanuary 11, 2020
Guilherme HaradaGilberto De Castro
8
1
2
Blood

The CNS can be a safe space for CARs

BloodSeptember 14, 2019
Carlos Almeida Ramos
17
7
Journal for Immunotherapy of Cancer

Multiple nivolumab-induced CNS demyelination with spontaneous resolution in an asymptomatic metastatic melanoma patient

Journal for Immunotherapy of CancerDecember 4, 2019
Vincent PillonelVeronica Aedo-Lopez
11
Proceedings of the National Academy of Sciences of the United States of America

Long-term in vivo microscopy of CAR T cell dynamics during eradication of CNS lymphoma in mice

Proceedings of the National Academy of Sciences of the United States of AmericaNovember 13, 2019
Matthias MulazzaniLouisa von Baumgarten
80
3
Multiple Sclerosis : Clinical and Laboratory Research

CNS demyelination after initiating the tyrosine kinase inhibitor imatinib: A report of two cases

Multiple Sclerosis : Clinical and Laboratory ResearchDecember 18, 2019
Dalia L RotsteinJeffrey H Lipton
8
bioRxiv

New Tools for Genetically Targeting Myeloid Populations in the Central Nervous System

bioRxivDecember 23, 2019
Gabriel L. McKinseyThomas D. Arnold
69
1
bioRxiv

Peripheral nerve resident macrophages are microglia-like cells with tissue-specific programming

bioRxivDecember 20, 2019
Peter L WangThe Immunological Genome Project
67
Critical Reviews in Oncology/hematology

Primary central nervous system lymphoma: Novel precision therapies

Critical Reviews in Oncology/hematologyJuly 12, 2019
Patrizia MondelloFrancesco Bertoni
7
13
Virchows Archiv : an International Journal of Pathology

Lymphomas arising in immune-privileged sites: insights into biology, diagnosis, and pathogenesis

Virchows Archiv : an International Journal of PathologyDecember 22, 2019
Rebecca L KingJudith A Ferry
4
1
Nature Immunology

Mechanisms of immunotherapy resistance: lessons from glioblastoma

Nature ImmunologyJuly 31, 2019
Christopher M JacksonMichael Lim
90
3
124
Cancer Letters

Immunotherapy for glioma: current management and future application

Cancer LettersFebruary 12, 2020
Shengchao XuZhixiong Liu
2
Revista médica del Instituto Mexicano del Seguro Social

Burkitt's lymphoma nodular cystic hepatosplenic, in HIV patient. Case report

Revista médica del Instituto Mexicano del Seguro SocialJanuary 30, 2020
Ibis De la Cruz-HernándezCarlos Alberto Mejía-Picasso
1
Critical Care Medicine

Critical Care Management of Toxicities Associated With Targeted Agents and Immunotherapies for Cancer

Critical Care MedicineNovember 15, 2019
Cristina GutierrezStephen M Pastores
39
3
4

See more papers from this feed

Related Feeds

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Cognitive Decline: Environmental And Genetic Factors

This feed focuses on the role of environmental and genetic factors including environmental policies, disease susceptibility, and socioeconomic status on cognitive decline. Here is the latest research.

Epigenetic Changes in Pain

Targeted epigenetic interventions provide the tools to prevent nociceptive sensitization, mood-related symptoms, and other adaptations that occur in response to injury or inflammation, which will facilitate pain management and improve treatment efficacy in many chronic pain conditions. Here is the latest research on the epigenetics changes in pain.

Epigenetic Regulation of Microglia Functions

Microglial cells are instrumental in the maintenance of homeostasis in the CNS and can contribute to neurodegenerative disorders. Epigenetic mechanisms and transcriptional regulation may be potential therapeutic targets for their activation or suppression. Discover the latest research on epigenetic regulation of microglial functions here.

Gene-Environment Interaction & Behaviour

Gene-environment interaction is when two different genotypes respond to environmental variation in different ways.Genes and environment interact to form an individual's personality. Abnormal or extreme behaviour could thus be explained by hereditary factors in combination with poor environmental conditions.

Genetic Influences on Brain Development

The genetic landscape of an individual can have drastic effects on brain development and brain developmental disorders. Discover the latest research here.

Genetic Networks Underlying Habituation

Habituation, the gradual waning of an evoked behavioral response with repeated stimulation, is a basic and universal form of learning. This feed explores the genetic networks that are involved in the occurence of habituation.

Genetic Screens in iPSC-Derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Genetics of Pain

Subtle changes in DNA could partly explain the variation in individual differences in pain. There is growing evidence that a number of genes play a critical role in determining pain sensitivity, pain reporting and susceptibility to developing chronic pain and their response to surgical outcomes primarily, pain.

Neurogenetic Disorders

Neurogenetic disorders are caused by a defect in one or more genes affecting the differentiation and function of the neuroectoderm and its derivatives. Here is the latest research on neurogenetic disorders

© 2020 Meta ULC. All rights reserved
/feed-previews/immunogenetics-of-cns-tumors/e9c69a88-0706-49c7-a424-be8017cec898