Immunogenetics of Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune disease for which over 100 genetic risk loci have been identified. Genes involved in T cell receptor signalling, the JAK-STAT signalling pathway, and NF-kB signalling are enriched. Find the latest research on the immunogenetics of rheumatoid arthritis here.

July 1, 2020

Integrative analysis highlighted susceptibility genes for rheumatoid arthritis

International Immunopharmacology
Xing-Bo MoShu-Feng Lei
June 23, 2020

Alterations in corneal biomechanics underlie early stages of autoimmune-mediated dry eye disease

Journal of Autoimmunity
Yael EfraimSarah M Knox
April 26, 2020

Discovery of diaminopyrimidine-carboxamide derivatives as JAK3 inhibitors

Bioorganic Chemistry
Rajesh BahekarRanjit C Desai
April 26, 2020

Association of Dickkopf-1 Polymorphisms With Radiological Damage and Periodontal Disease in Patients With Early Rheumatoid Arthritis: A Cross-Sectional Study

Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases
Alex Dario Cardona-RincónConsuelo Romero-Sánchez
June 18, 2020
Open Access

S1P promotes IL-6 expression in osteoblasts through the PI3K, MEK/ERK and NF-κB signaling pathways

International Journal of Medical Sciences
Sung-Lin HuChih-Hsin Tang
May 20, 2020

Macrophage migration inhibitory factor gene polymorphisms as exacerbating factors of apical periodontitis

Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University
Andrea Freer-RojasJorge Alejandro Alegría-Torres
April 21, 2020

Optineurin in Synovial Fibroblasts Plays a Protective Role against Joint Destructions in Rheumatoid Arthritis

Arthritis & Rheumatology
Wen Shi LeeTatsuya Atsumi
April 10, 2020

TGF-β1 +869C/T polymorphism increases susceptibility to rheumatoid arthritis in North Indian population

Clinical Rheumatology
Sipahee Lal PatelVarsha Gupta
April 25, 2020
Open Access

Modified entropy-based procedure detects gene-gene-interactions in unconventional genetic models

BMC Medical Genomics
Jörg Malten, Inke R König
May 1, 2020
Open Access

Causal effects of senescence through intrinsic epigenetic age acceleration on age-related diseases: a Mendelian randomization study

MedRxiv : the Preprint Server for Health Sciences
Francesco Gatto, P. Ueda
June 24, 2020
Open Access

Modifiable environmental exposure and risk of rheumatoid arthritis-current evidence from genetic studies

Arthritis Research & Therapy
Xia Jiang, Lars Alfredsson
April 8, 2020
Open Access

Relationship between miR-155 and miR-146a polymorphisms and susceptibility to multiple sclerosis in an Egyptian cohort

Biomedical Reports
Marwa Ahmed AliSylvana Nady Gaber

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