Immunogenetics of Systemic Lupus Erythematosus

SLE is an autoimmune disease whose cause remains unclear and for which only symptomatic treatments currently exist. Linking the genetic and epigenetic assocations to molecular pathways and cellular phenotype is required to understand this disease and advance therapeutics. Find the latest research on the immunnogenetics of SLE here.

October 25, 2021
Preprint
Open Access

Autotaxin may play a Critical Role between the Genetic Risk Factors and Pathogenesis of SLE in Plasmacytoid Dendritic Cells

BioRxiv : the Preprint Server for Biology
Y. TsuchidaT. Sawada
October 24, 2021
Review
Open Access

The Pathogenesis, Molecular Mechanisms, and Therapeutic Potential of the Interferon Pathway in Systemic Lupus Erythematosus and Other Autoimmune Diseases.

International Journal of Molecular Sciences
Madhu RamaswamyPhilip Z Brohawn
October 20, 2021

Profound inhibition of CD73-dependent formation of anti-inflammatory adenosine in B cells of SLE patients.

EBioMedicine
Julia HesseGeorg Pongratz
October 20, 2021

Autoantibodies against the envelope proteins of endogenous retroviruses K102 and K108 in patients with systemic lupus erythematosus correlate with active disease.

Clinical and Experimental Rheumatology
Anastasia I KhadjinovaTomas Mustelin
October 18, 2021
Review

Molecular mechanisms of vasculopathy and coagulopathy in COVID-19.

Biological Chemistry
Suzan Al-GburiClaudia Günther
October 13, 2021
Review
Open Access

Regulation of B Cell Responses in SLE by Three Classes of Interferons.

International Journal of Molecular Sciences
Phillip P Domeier, Ziaur S M Rahman
October 11, 2021

Programmed cell death-1 rs11568821 and interleukin-28B rs12979860 polymorphisms in autoimmune hepatitis.

Journal of Translational Autoimmunity
Nikolaos K GatselisGeorge N Dalekos
October 9, 2021
Preprint
Open Access

Immune cell multi-omics analysis reveals contribution of oxidative phosphorylation to B cell functions and organ damage of lupus

BioRxiv : the Preprint Server for Biology
Y. TakeshimaKeishi Fujio
October 8, 2021
Open Access

Autoimmune Regulator Gene Polymorphisms in Egyptian Systemic Lupus Erythematosus Patients: Preliminary Results.

International Journal of Rheumatology
Doaa Hs AttiaRadwa M Abdel Halim
October 4, 2021

CD4+ T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases.

Epigenetics : Official Journal of the DNA Methylation Society
Tejaswi V BadamJan Ernerudh
October 4, 2021
Review
Open Access

Novel Roles of the Tim Family in Immune Regulation and Autoimmune Diseases.

Frontiers in Immunology
Yikai LiuZhiguang Zhou
October 2, 2021
Review

Fatigue in inflammatory rheumatic diseases: current knowledge and areas for future research.

Nature Reviews. Rheumatology
Kristen DaviesWan-Fai Ng
October 2, 2021

Schizophrenia Genetics and Neuropsychiatric Features in Childhood-Onset Systemic Lupus Erythematosus.

The Journal of Rheumatology
Ana C UlloaLinda T Hiraki

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