Immunogenetics of Systemic Lupus Erythematosus

SLE is an autoimmune disease whose cause remains unclear and for which only symptomatic treatments currently exist. Linking the genetic and epigenetic assocations to molecular pathways and cellular phenotype is required to understand this disease and advance therapeutics. Find the latest research on the immunnogenetics of SLE here.

July 21, 2020
Open Access

Understanding the genetics of systemic lupus erythematosus using Bayesian statistics and gene network analysis

Clinical and Experimental Pediatrics
Seoung Wan NamAndreas Kronbichler
September 11, 2020

Modulation of cardiometabolic disease markers by type I interferon inhibition in systemic lupus erythematosus

Arthritis & Rheumatology
Kerry A CaseyWendy I White
August 28, 2020
Open Access

Association of microRNA 17 host gene variant (rs4284505) with susceptibility and severity of systemic lupus erythematosus

Immunity, Inflammation and Disease
Abdelhady R Abdel-GawadNawal S Gouda
June 23, 2020

Alterations in corneal biomechanics underlie early stages of autoimmune-mediated dry eye disease

Journal of Autoimmunity
Yael EfraimSarah M Knox
August 19, 2020

Splicing factor SRSF1 limits IFN-γ production via RhoH and ameliorates experimental nephritis

Takayuki KatsuyamaVaishali R Moulton
August 11, 2020
Open Access

Nearest-Neighbor Projected Distance Regression for Epistasis Detection in GWAS With Population Structure Correction

Frontiers in Genetics
Marziyeh ArabnejadBrett A McKinney
October 20, 2020
Open Access

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

Frontiers in Immunology
Gantsetseg TumurkhuuMoshe Arditi
July 2, 2020

Rethinking the Pathogenesis of Cutaneous Lupus

The Journal of Investigative Dermatology
J Michelle Kahlenberg
October 22, 2020
Open Access

MYSM1 Represses Innate Immunity and Autoimmunity through Suppressing the cGAS-STING Pathway

Cell Reports
Mingfu TianJianguo Wu
August 12, 2020
Open Access

MicroRNAs in autoimmune liver diseases: from diagnosis to potential therapeutic targets

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Chen HuangLi Yang
October 11, 2020
Open Access

Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

Annals of the Rheumatic Diseases
Johanna K SandlingLars Rönnblom

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