Immunoglobulin Somatic Hypermutation

DNA editing by the cytidine deaminase aid mediates immunoglobulin somatic hypermutation and class switch recombination, providing the antibody response with the flexibility and diversity to defend against an almost limitless array of varied and rapidly adapting pathogenic challenges. Discover the latest research on immunoglobulin somatic hypermutation here.

June 9, 2020

Clinical and Molecular Correlates of Tumor Mutation Burden in Non-Small Cell Lung Cancer

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Michael F SharpnackKai He
August 8, 2020
Open Access

Germline RAD54L with somatic POLE defect implicated in Hypermutation phenotype: case report

BMC Gastroenterology
Bisan Abdalfatah ZohudXin Cai
July 30, 2020

Deciphering the vascular labyrinth: role of microRNAs and candidate gene SNPs in brain AVM development - literature review

Neurological Research
Ioan Alexandru FlorianIoana Berindan-Neagoe
August 9, 2020

Fatal outcome of chikungunya virus infection in Brazil

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Shirlene Telmos Silva de LimaFabio Miyajima
August 9, 2020
Open Access

Advances in understanding the evolution of fungal genome architecture

Shelby J PriestJoseph Heitman
July 22, 2020
Open Access

Learning the heterogeneous hypermutation landscape of immunoglobulins from high-throughput repertoire data

BioRxiv : the Preprint Server for Biology
Natanael SpisakThierry Mora
June 9, 2020
Case Report
Open Access

Immune Modulation for Enzyme Replacement Therapy in A Female Patient With Hunter Syndrome

Frontiers in Immunology
Daniel C JulienPriya S Kishnani
July 10, 2020
Open Access

A case of ezetimibe-effective hypercholesterolemia with a novel heterozygous variant in ABCG5

Endocrine Journal
Yujiro NakanoTetsuya Yamada
July 6, 2020
Open Access

Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity

BioRxiv : the Preprint Server for Biology
A. GraudenziDaniele Ramazzotti
June 23, 2020
Open Access

Comprehensive characterization of driver genes in diffuse large B cell lymphoma

Oncology Letters
Zheng FanYing Lu
August 5, 2020

DNA mismatch repair promotes APOBEC3-mediated diffuse hypermutation in human cancers

Nature Genetics
David Mas-Ponte, Fran Supek

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