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Immunological Genome Project

Immunological Genome Project  diagram by Alpha Tauri 3D Graphics, Wikimedia
Alpha Tauri 3D Graphics, Wikimedia

The Immunological Genome Project (ImmGen) aims to build a gene expression database for murine immune cells. This will allow for the computational reconstruction of genetic regulatory networks across the immune system. Follow the latest research from ImmGen researchers here.

Top 20 most recent papers
Cell

Universal Principled Review: A Community-Driven Method to Improve Peer Review

CellDecember 14, 2019
Matthew KrummelFuture Immunology Consortium
581
2
1
1
Cell

Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

CellSeptember 3, 2019
Jerome C MartinEphraim Kenigsberg
195
5
1
153
Immunity

Reinvigorating NIH Grant Peer Review

ImmunityJanuary 16, 2020
Shane CrottyOnce-a-Year Pledge Supporters
162
Nature Immunology

Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis

Nature ImmunologyAugust 15, 2019
Arnon AraziAccelerating Medicines Partnership in SLE network
1
15
Cell

Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease

CellDecember 24, 2019
June-Yong LeeDan R Littman
70
3
bioRxiv

CXCR4-binding PET tracers link monocyte recruitment and endothelial injury in murine atherosclerosis

bioRxivJanuary 2, 2020
Gwendalyn J RandolphYongjian Liu
11
bioRxiv

Peripheral nerve resident macrophages are microglia-like cells with tissue-specific programming

bioRxivDecember 20, 2019
Peter L Wangthe Immunological Genome Project
65
Blood Advances

Circulating CD1c+ myeloid dendritic cells are potential precursors to LCH lesion CD1a+CD207+ cells

Blood AdvancesJanuary 4, 2020
Karen Phaik Har LimCarl E Allen
4
Cell

Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool

CellAugust 24, 2019
Stefan JordanMiriam Merad
714
22
6
172
1
1
1
Cancer Discovery

Single-cell RNA sequencing reveals stromal evolution into LRRC15+ myofibroblasts as a determinant of patient response to cancer immunotherapy

Cancer DiscoveryNovember 9, 2019
Claudia X DominguezShannon Turley
36
1
14
bioRxiv

Learning immune cell differentiation

bioRxivDecember 23, 2019
Alexandra Maslovathe Immunological Genome Project
60
bioRxiv

DNA Break-Induced Epigenetic Drift as a Cause of Mammalian Aging

bioRxivOctober 21, 2019
Motoshi HayanoDavid A. Sinclair
187
Methods in Molecular Biology

Multiplexed Immunohistochemical Consecutive Staining on Single Slide (MICSSS): Multiplexed Chromogenic IHC Assay for High-Dimensional Tissue Analysis

Methods in Molecular BiologySeptember 11, 2019
Guray AkturkSacha Gnjatic
8
6
JCI Insight

Myocardial B cells are a subset of circulating lymphocytes with delayed transit through the heart

JCI InsightJanuary 17, 2020
Luigi AdamoDouglas Mann
bioRxiv

Immune Profiling of Atherosclerotic Plaques Identifies Innate and Adaptive Dysregulations Associated with Ischemic Cerebrovascular Events

bioRxivAugust 2, 2019
Dawn M FernandezChiara Giannarelli
47
12
Cancer Discovery

Antitumor T-cell Homeostatic Activation Is Uncoupled from Homeostatic Inhibition by Checkpoint Blockade

Cancer DiscoveryAugust 4, 2019
Netonia MarshallJoshua D Brody
20
17
23
bioRxiv

Post-EMT: Cadherin-11 mediates cancer hijacking fibroblasts

bioRxivAugust 9, 2019
Weirong KangZhizhan Gu
6
5
Nature Immunology

Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling

Nature ImmunologyOctober 23, 2019
Flavian D BrownShannon Turley
44
48
1
bioRxiv

Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Transcriptional and Biochemical Function

bioRxivOctober 17, 2019
Conor N GruberDusan Bogunovic
61
7
Molecular & Cellular Proteomics : MCP

A platform for extracellular interactome discovery identifies novel functional binding partners for the immune receptors B7-H3/CD276 and PVR/CD155

Molecular & Cellular Proteomics : MCPJuly 17, 2019
Bushra HusainNadia Martinez-Martin
9
11

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