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Immunological Genome Project

Immunological Genome Project  diagram by Alpha Tauri 3D Graphics, Wikimedia
Alpha Tauri 3D Graphics, Wikimedia

The Immunological Genome Project (ImmGen) aims to build a gene expression database for murine immune cells. This will allow for the computational reconstruction of genetic regulatory networks across the immune system. Follow the latest research from ImmGen researchers here.

Top 20 most recent papers
The Journal of Biological Chemistry

Relative stabilities of wild-type and mutant glial fibrillary acidic protein in patients with Alexander disease

The Journal of Biological ChemistrySeptember 6, 2019
Michael R HeavenMichael B Brenner
5
2
Nature Methods

Fast, sensitive and accurate integration of single-cell data with Harmony

Nature MethodsNovember 20, 2019
Ilya KorsunskySoumya Raychaudhuri
184
12
Proceedings of the National Academy of Sciences of the United States of America

Neutrophils promote VLA-4-dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation

Proceedings of the National Academy of Sciences of the United States of AmericaNovember 9, 2019
Chelsea R Parker HarpGregory F Wu
25
19
Nature Medicine

Single-cell immune landscape of human atherosclerotic plaques

Nature MedicineOctober 9, 2019
Dawn M FernandezChiara Giannarelli
303
3
8
103
1
Nature Genetics

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

Nature GeneticsFebruary 19, 2020
Maria Gutierrez-ArcelusSoumya Raychaudhuri
45
1
Proceedings of the National Academy of Sciences of the United States of America

T cell receptor specificity drives accumulation of a reparative population of regulatory T cells within acutely injured skeletal muscle

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 12, 2019
Jun ChoDiane Mathis
8
Nature Immunology

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

Nature ImmunologySeptember 20, 2019
Nathan W ZammitShane T Grey
35
25
31
1
63
50
1
Nature

Antitumour T cells stand the test of time

NatureDecember 18, 2019
Miguel Reina-Campos, Ananda W Goldrath
71
1
2
Cell

Universal Principled Review: A Community-Driven Method to Improve Peer Review

CellDecember 14, 2019
Matthew KrummelFuture Immunology Consortium
594
2
1
1
207
2
1
Immunity

Reinvigorating NIH Grant Peer Review

ImmunityJanuary 16, 2020
Shane CrottyOnce-a-Year Pledge Supporters
163
108
1
3
Immunological Reviews

Visceral adipose tissue Tregs and the cells that nurture them

Immunological ReviewsMarch 13, 2020
Chaoran LiDiane Mathis
10

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