Immunotherapy (Preprints)

Cancer immunotherapy is an important field of research that is looking at controlling cancer and tumor growth by activating the individuals own immune system. Recent studies have utilized chimeric antigen receptor t-cell therapy, immune checkpoint inhibitors and neoantigen vaccines. Discover the latest preprints on cancer immunotherapy here.

July 26, 2020
Preprint
Open Access

De novo designed receptor transmembrane domains enhance CAR-T cell cytotoxicity and attenuate cytokine release

BioRxiv : the Preprint Server for Biology
A. ElazarSarel J Fleishman
September 1, 2020
Preprint
Open Access

Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion

BioRxiv : the Preprint Server for Biology
C. J. FrangiehBenjamin Izar
August 12, 2020
Preprint
Open Access

Preclinical modeling of surgery and steroid therapy for glioblastoma reveals changes in immunophenotype that are associated with tumor growth and outcome

BioRxiv : the Preprint Server for Biology
B. OtvosJustin D Lathia
July 24, 2020
Preprint
Open Access

High-Plex and High-throughput Digital Spatial Profiling of non-small-cell lung cancer (NSCLC)

MedRxiv : the Preprint Server for Health Sciences
J. MonkmanArutha Kulasinghe
August 22, 2020
Preprint
Open Access

Alternative splicing of SLAMF6 in human T cells creates a co-stimulatory isoform that counteracts the inhibitory effect of the full-length receptor

BioRxiv : the Preprint Server for Biology
Emma HajajM. Lotem
September 13, 2020
Preprint
Open Access

Phospho-β-catenin expression in primary and metastatic melanomas and in tumor-free visceral tissues

BioRxiv : the Preprint Server for Biology
J. PinczewskiV. H. Engelhard
August 13, 2020
Preprint
Open Access

RNA Editing Signatures Predict Response to Immunotherapies in Melanoma Patients

BioRxiv : the Preprint Server for Biology
J. K. Siddiqui, Wayne O Miles
August 12, 2020
Preprint
Open Access

Efficacy of Targeting SARS-CoV-2 by CAR-NK Cells

BioRxiv : the Preprint Server for Biology
M. T. MaDongfang Liu
July 22, 2020
Preprint
Open Access

Toxicities of PD-1/PD-L1 Inhibitors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

MedRxiv : the Preprint Server for Health Sciences
X. KongJ. Wang
July 30, 2020
Preprint
Open Access

Base-edited CAR T Cells for combinational therapy against T cell malignancies

BioRxiv : the Preprint Server for Biology
C. GeorgiadisWaseem Qasim
August 20, 2020
Preprint
Open Access

Enterococcus peptidoglycan remodeling promotes immune checkpoint inhibitor therapy

BioRxiv : the Preprint Server for Biology
M. E. GriffinHoward C Hang
July 29, 2020
Preprint
Open Access

Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases

MedRxiv : the Preprint Server for Health Sciences
A. ThompsonSimon H Mead
July 29, 2020
Preprint
Open Access

PLEKHA4 Promotes Wnt/β-catenin Signaling-Mediated G1/S Transition and Proliferation in Melanoma

BioRxiv : the Preprint Server for Biology
A. Shami ShahJeremy M Baskin
August 20, 2020
Preprint
Open Access

Human cytokine-induced memory-like NK cells preserve increased glycolysis but the glycolytic-dependence of their effector functions differ between stimuli

BioRxiv : the Preprint Server for Biology
I. TerrenFrancisco Borrego
September 8, 2020
Preprint
Open Access

Ly6C defines a subset of memory-like CD27+ γδ T cells with inducible cancer-killing function

BioRxiv : the Preprint Server for Biology
R. WiesheuSeth B Coffelt
July 24, 2020
Preprint
Open Access

Immuno-informatics approach for multi-epitope vaccine designing against SARS-CoV-2

BioRxiv : the Preprint Server for Biology
Souvik BanerjeeB. Mittal
July 22, 2020
Preprint
Open Access

dN/dS dynamics quantify tumour immunogenicity and predict response to immunotherapy

BioRxiv : the Preprint Server for Biology
Luis ZapataA. Sottoriva
July 23, 2020
Preprint
Open Access

Use of IL-6-elafin genetically modified regulatory macrophages as an immunotherapeutic against acute bacterial infection in the lung

BioRxiv : the Preprint Server for Biology
S. KheirJean-Michel Sallenave
July 29, 2020
Preprint
Open Access

Paracoccidioides HSP90 can be found in the cell surface and is a target for antibodies with therapeutic potential

BioRxiv : the Preprint Server for Biology
A. N. D. MouraAndré Moraes Nicola

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