Immunotherapy (Preprints)

Cancer immunotherapy is an important field of research that is looking at controlling cancer and tumor growth by activating the individuals own immune system. Recent studies have utilized chimeric antigen receptor t-cell therapy, immune checkpoint inhibitors and neoantigen vaccines. Discover the latest preprints on cancer immunotherapy here.

February 25, 2021
Preprint
Open Access

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.

BioRxiv : the Preprint Server for Biology
M. PanP. Geeleher
February 25, 2021
Preprint
Open Access

The immunophilin protein FKBPL and its peptide derivatives are novel regulators of vascular integrity and inflammation via NF-kappaB signaling

BioRxiv : the Preprint Server for Biology
S. L. AnnettTracy Robson
February 24, 2021
Preprint
Open Access

MYC promotes immune-suppression in TNBC via inhibition of IFN signaling

BioRxiv : the Preprint Server for Biology
D. ZimmerliJos Jonkers
February 23, 2021
Preprint
Open Access

Single-cell sequencing characterizes intratumoral profile of immune cells in old mice

BioRxiv : the Preprint Server for Biology
Baojun ZhangBaojun Zhang
February 22, 2021
Preprint
Open Access

Human immunocompetent Organs-on-Chips platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

BioRxiv : the Preprint Server for Biology
Lauriane CabonR. Barrile
February 12, 2021
Preprint
Open Access

Elucidating Mechanisms of Antitumor Immunity Mediated by Live Oncolytic Vaccinia and Heat-Inactivated Vaccinia

BioRxiv : the Preprint Server for Biology
W. WangLiang Deng
February 10, 2021
Preprint
Open Access

Embedding of exogenous B cell epitopes on the surface of UreB structure generates a broadly reactive antibody response against Helicobacter pylori

BioRxiv : the Preprint Server for Biology
J. MaQing Liu
February 8, 2021
Preprint
Open Access

Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma

BioRxiv : the Preprint Server for Biology
E. AliagasErnest Nadal
February 5, 2021
Preprint
Open Access

Standing Variations Modeling Captures Inter-Individual Heterogeneity in a Deterministic Model of Prostate Cancer Response to Combination Therapy

BioRxiv : the Preprint Server for Biology
Harsh JainT. L. Jackson
February 5, 2021
Preprint
Open Access

Sublingual allergen immunotherapy with recombinant dog allergens prevents airway hyperresponsiveness in a model of asthma marked by vigorous TH2 and TH17 cell responses

BioRxiv : the Preprint Server for Biology
Jonathan M CoquetG. Gafvelin
February 4, 2021
Preprint
Open Access

High Affinity Chimeric Antigen Receptor with Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms

BioRxiv : the Preprint Server for Biology
R. ThokalaDonald M O'Rourke
February 4, 2021
Preprint
Open Access

Epigenetic therapy to enhance therapeutic effects of PD-1 inhibition in uveal melanoma

BioRxiv : the Preprint Server for Biology
V. R. SahJonas A Nilsson
February 4, 2021
Preprint
Open Access

Bladder Cancer Immunotherapy by BCG is associated with a significantly reduced risk of Alzheimer disease

MedRxiv : the Preprint Server for Health Sciences
D. KlingerH. Bercovier
February 2, 2021
Preprint
Open Access

Spatial and temporal plasticity of neoantigen-specific T-cell responses bases on characteristics associated to antigen and TCR

BioRxiv : the Preprint Server for Biology
E. BraeunleinAngela M Krackhardt
February 2, 2021
Preprint
Open Access

Cannabinoids is a "No-Go" While a Cancer Patient is on Immunotherapy; but is It Safe to Use Psychedelics During Cancer Immunotherapy?

BioRxiv : the Preprint Server for Biology
Einat Amit RomachI. Lamensdorf
February 2, 2021
Preprint
Open Access

The Prognostic Value of Tumor-Infiltrating Immune Cells in Gynecologic Cancers

BioRxiv : the Preprint Server for Biology
W. ChenChunbo He
February 1, 2021
Preprint
Open Access

Novel EGFRvIII-CAR transgenic mice for rigorous preclinical studies in syngeneic mice

BioRxiv : the Preprint Server for Biology
P. ChuntovaHideho Okada
February 1, 2021
Preprint
Open Access

IgG1 pan-neurofascin antibodies identify a severe yet treatable neuropathy with a high mortality

MedRxiv : the Preprint Server for Health Sciences
J. FehmiSimon Rinaldi
January 30, 2021
Preprint
Open Access

Transcutaneous penetration of a single-chain variable fragment (scFv) compared to a full-size antibody: potential tool for Atopic Dermatitis (AD) treatment

BioRxiv : the Preprint Server for Biology
A. BayletLaurent Delpy

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