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Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells diagram by metamorworks, Shutterstock
metamorworks, Shutterstock

Induced pluripotent stem cells (iPSCs) may be obtained by direct reprogramming of different somatic cells to a pluripotent state by forced expression of a handful of transcription factors, These cells have similar properties to those of embryonic stem cells (escs) but bypass the ethical concerns of embryo destruction and can be exploited for both research and clinical applications.Discover the latest research on iPSC here.

Top 20 most recent papers
May 24, 2020

Extra-telomeric impact of telomeres: Emerging molecular connections in pluripotency or stemness

The Journal of Biological Chemistry
Soujanya VinayagamurthyShantanu Chowdhury
May 23, 2020

Generation and characterization of HLA-universal platelets derived from induced pluripotent stem cells

Scientific Reports
Phatchara NorbnopVorasuk Shotelersuk
May 22, 2020

Concise Review: Harnessing iPSC-derived Cells for Ischemic Heart Disease Treatment

Journal of Translational Internal Medicine
Bin Duan
May 21, 2020

METTL1 limits differentiation and functioning of EPCs derived from human-induced pluripotent stem cells through a MAPK/ERK pathway

Biochemical and Biophysical Research Communications
Yujie DengBeixin Yu
May 21, 2020

In Vitro and In Vivo Interspecies Chimera Assay Using Early Pig Embryos

Cellular Reprogramming
Monika Nowak-ImialekHeiner Niemann
May 19, 2020
Open Access

Live-cell screening platform using human-induced pluripotent stem cells expressing fluorescence-tagged cytochrome P450 1A1

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Ji-Woo KimHan-Jin Park
May 24, 2020

Generation of a human iPSC line (MPIi006-A) from a patient with Pelizaeus-Merzbacher disease

Stem Cell Research
Kee-Pyo KimHans R Schöler
May 20, 2020

Longitudinal metabolic profiling of cardiomyocytes derived from human-induced pluripotent stem cells

Basic Research in Cardiology
Mohamed M BekhiteP Christian Schulze
May 19, 2020

Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates

Neurobiology of Disease
Philippe GossetFrancesca Cicchetti

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