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Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells diagram by metamorworks, Shutterstock
metamorworks, Shutterstock

Induced pluripotent stem cells (iPSCs) may be obtained by direct reprogramming of different somatic cells to a pluripotent state by forced expression of a handful of transcription factors, These cells have similar properties to those of embryonic stem cells (escs) but bypass the ethical concerns of embryo destruction and can be exploited for both research and clinical applications.Discover the latest research on iPSC here.

Top 20 most recent papers

Maturation of human induced pluripotent stem cell-derived cardiomyocytes for modeling hypertrophic cardiomyopathy

bioRxivJanuary 17, 2020
Walter E. KnightKunhua Song
The EMBO Journal

Autophagy mediates temporary reprogramming and dedifferentiation in plant somatic cells

The EMBO JournalJanuary 14, 2020
Eleazar RodriguezMorten Petersen

Sox2 modulation increases naive pluripotency plasticity

bioRxivJanuary 15, 2020
Kathryn TrembleJose C. R. Silva
Scientific Reports

Troponin destabilization impairs sarcomere-cytoskeleton interactions in iPSC-derived cardiomyocytes from dilated cardiomyopathy patients

Scientific ReportsJanuary 16, 2020
Yuanyuan DaiAntje Ebert
Molecular Neurobiology

Correction to: Progerin-Induced Transcriptional Changes in Huntington's Disease Human Pluripotent Stem Cell-Derived Neurons

Molecular NeurobiologyJanuary 16, 2020
Dorit Cohen-CarmonEran Meshorer
Cell Reports

p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells

Cell ReportsJanuary 16, 2020
Qiang LiRajesh C Rao
Nature Communications

Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency

Nature CommunicationsJanuary 12, 2020
Ryoko ArakiMasumi Abe
Scientific Reports

Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling

Scientific ReportsJanuary 17, 2020
Thomas Aga LegøySimona Chera
Biotechnology Progress

Generation of keratinocyte stem-like cells from human fibroblasts via a direct reprogramming approach

Biotechnology ProgressJanuary 14, 2020
Andong ZhaoSa Cai
International Journal of Molecular Sciences

Human Induced Pluripotent Stem Cells Derived from a Cardiac Somatic Source: Insights for an In-Vitro Cardiomyocyte Platform

International Journal of Molecular SciencesJanuary 17, 2020
Alessandra Maria LodriniClaudia Altomare
Inflammation and Regeneration

Toward the realization of cardiac regenerative medicine using pluripotent stem cells

Inflammation and RegenerationJanuary 16, 2020
Yoshikazu KishinoKeiichi Fukuda
International Journal of Molecular Sciences

Progress of Induced Pluripotent Stem Cell Technologies to Understand Genetic Epilepsy

International Journal of Molecular SciencesJanuary 17, 2020
Bruno SterliniAnna Corradi
Scientific Reports

Efficient generation of thymic epithelium from induced pluripotent stem cells that prolongs allograft survival

Scientific ReportsJanuary 16, 2020
Ryo OtsukaKen-Ichiro Seino
FEBS Open Bio

Benzothiazole amphiphiles promote RasGRF1-associated dendritic spine formation in human stem cell-derived neurons

FEBS Open BioJanuary 17, 2020
Jessica L CifelliJerry Yang
Stem Cell Reports

Negligible-Cost and Weekend-Free Chemically Defined Human iPSC Culture

Stem Cell ReportsJanuary 14, 2020
Hui-Hsuan KuoPaul W Burridge
Journal of Biomedical Materials Research. Part B, Applied Biomaterials

Thermosensitive hydrogels loaded with human-induced pluripotent stem cells overexpressing growth differentiation factor-5 ameliorate intervertebral disc degeneration in rats

Journal of Biomedical Materials Research. Part B, Applied BiomaterialsJanuary 14, 2020
Annan HuJian Dong
International Journal of Clinical and Experimental Pathology

MicroRNA-23 inhibition protects the ischemia/reperfusion injury via inducing the differentiation of bone marrow mesenchymal stem cells into cardiomyocytes

International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Mingjun LuZhiyong Liu

Cytokine Directed Chondroblast Trans-Differentiation: JAK Inhibition Facilitates Direct Reprogramming of Fibroblasts to Chondroblasts

CellsJanuary 17, 2020
Perla CotaDerrick E Rancourt
International Journal of Molecular Sciences

Clinical Trials of Limbal Stem Cell Deficiency Treated with Oral Mucosal Epithelial Cells

International Journal of Molecular SciencesJanuary 16, 2020
Joan OlivaYutaka Niihara
Annals of Translational Medicine

A compendious summary of Parkinson's disease patient-derived iPSCs in the first decade

Annals of Translational MedicineJanuary 14, 2020
Chao RenChun-Feng Liu

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