Induced Pluripotent Stem Cells

Induced pluripotent stem cells (iPSCs) may be obtained by direct reprogramming of different somatic cells to a pluripotent state by forced expression of a handful of transcription factors, These cells have similar properties to those of embryonic stem cells (escs) but bypass the ethical concerns of embryo destruction and can be exploited for both research and clinical applications.Discover the latest research on iPSC here.

January 16, 2022

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.

Cell Stem Cell
Jitske JansenRafael Kramann
January 15, 2022
Open Access

Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson's disease.

Communications Biology
Gabriela NovakAlexander Skupin
January 15, 2022
Open Access

General gene expression patterns and stemness of the gingiva and dental pulp.

Journal of Dental Sciences
Ko Eun LeeHyung-Jun Choi
January 15, 2022

Comprehensive analyses of the inotropic compound omecamtiv mecarbil in rat and human cardiac preparations.

American Journal of Physiology. Heart and Circulatory Physiology
Alexandra RhodenThomas Eschenhagen
January 15, 2022

Inducing human retinal pigment epithelium-like cells from somatic tissue.

Stem Cell Reports
Ivo Ngundu WoogengCody Kime
January 15, 2022

PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids.

Stem Cell Reports
Nobuhiko ShirakiKohji Nishida
January 14, 2022
Comment / Editorial

in vitro models of human mast cells: How to get more and better with induced pluripotent stem cells?

The Journal of Allergy and Clinical Immunology
Laurent L'homme, David Dombrowicz
January 14, 2022

Generation of two iPSC lines from healthy donor with a heterozygous mutation in the VPS13B gene.

Stem Cell Research
S A ChechetkinaI E Pristyazhnyuk
January 14, 2022

Inhibiting mitochondrial fission rescues degeneration in hereditary spastic paraplegia neurons.

Brain : a Journal of Neurology
Zhenyu ChenXue-Jun Li
January 14, 2022

Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function.

Current Protocols
Shuk Yee NganAmy P Wong
January 14, 2022
Open Access

Dendritic Polyglycerol Amine: An Enhanced Substrate to Support Long-Term Neural Cell Culture.

ASN Neuro
Jean-Pierre ClémentTimothy E Kennedy
January 14, 2022

Skin Mirrors Brain: A Chance for Alzheimer's Disease Research.

Advances in Experimental Medicine and Biology
Christos C ZouboulisAmir M Hossini
January 13, 2022

Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance.

Proceedings of the National Academy of Sciences of the United States of America
Stephanie Cerceo PageBrady J Maher

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