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Induced Pluripotent Stem Cells
metamorworks, ShutterstockInduced pluripotent stem cells (iPSCs) may be obtained by direct reprogramming of different somatic cells to a pluripotent state by forced expression of a handful of transcription factors, These cells have similar properties to those of embryonic stem cells (escs) but bypass the ethical concerns of embryo destruction and can be exploited for both research and clinical applications.Discover the latest research on iPSC here.
Top 20 most recent papers
Maturation of human induced pluripotent stem cell-derived cardiomyocytes for modeling hypertrophic cardiomyopathy
bioRxivJanuary 17, 2020
Walter E. KnightKunhua Song
4
Autophagy mediates temporary reprogramming and dedifferentiation in plant somatic cells
The EMBO JournalJanuary 14, 2020
Eleazar RodriguezMorten Petersen
6
3
Sox2 modulation increases naive pluripotency plasticity
bioRxivJanuary 15, 2020
Kathryn TrembleJose C. R. Silva
10
Troponin destabilization impairs sarcomere-cytoskeleton interactions in iPSC-derived cardiomyocytes from dilated cardiomyopathy patients
Scientific ReportsJanuary 16, 2020
Yuanyuan DaiAntje Ebert
7
Correction to: Progerin-Induced Transcriptional Changes in Huntington's Disease Human Pluripotent Stem Cell-Derived Neurons
Molecular NeurobiologyJanuary 16, 2020
Dorit Cohen-CarmonEran Meshorer
3
p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells
Cell ReportsJanuary 16, 2020
Qiang LiRajesh C Rao
26
1
1
Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency
Nature CommunicationsJanuary 12, 2020
Ryoko ArakiMasumi Abe
1
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
Scientific ReportsJanuary 17, 2020
Thomas Aga LegøySimona Chera
3
Generation of keratinocyte stem-like cells from human fibroblasts via a direct reprogramming approach
Biotechnology ProgressJanuary 14, 2020
Andong ZhaoSa Cai
Human Induced Pluripotent Stem Cells Derived from a Cardiac Somatic Source: Insights for an In-Vitro Cardiomyocyte Platform
International Journal of Molecular SciencesJanuary 17, 2020
Alessandra Maria LodriniClaudia Altomare
3
Toward the realization of cardiac regenerative medicine using pluripotent stem cells
Inflammation and RegenerationJanuary 16, 2020
Yoshikazu KishinoKeiichi Fukuda
2
Progress of Induced Pluripotent Stem Cell Technologies to Understand Genetic Epilepsy
International Journal of Molecular SciencesJanuary 17, 2020
Bruno SterliniAnna Corradi
1
Efficient generation of thymic epithelium from induced pluripotent stem cells that prolongs allograft survival
Scientific ReportsJanuary 16, 2020
Ryo OtsukaKen-Ichiro Seino
3
1
Benzothiazole amphiphiles promote RasGRF1-associated dendritic spine formation in human stem cell-derived neurons
FEBS Open BioJanuary 17, 2020
Jessica L CifelliJerry Yang
1
Negligible-Cost and Weekend-Free Chemically Defined Human iPSC Culture
Stem Cell ReportsJanuary 14, 2020
Hui-Hsuan KuoPaul W Burridge
56
2
Thermosensitive hydrogels loaded with human-induced pluripotent stem cells overexpressing growth differentiation factor-5 ameliorate intervertebral disc degeneration in rats
Journal of Biomedical Materials Research. Part B, Applied BiomaterialsJanuary 14, 2020
Annan HuJian Dong
MicroRNA-23 inhibition protects the ischemia/reperfusion injury via inducing the differentiation of bone marrow mesenchymal stem cells into cardiomyocytes
International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Mingjun LuZhiyong Liu
Cytokine Directed Chondroblast Trans-Differentiation: JAK Inhibition Facilitates Direct Reprogramming of Fibroblasts to Chondroblasts
CellsJanuary 17, 2020
Perla CotaDerrick E Rancourt
Clinical Trials of Limbal Stem Cell Deficiency Treated with Oral Mucosal Epithelial Cells
International Journal of Molecular SciencesJanuary 16, 2020
Joan OlivaYutaka Niihara
A compendious summary of Parkinson's disease patient-derived iPSCs in the first decade
Annals of Translational MedicineJanuary 14, 2020
Chao RenChun-Feng Liu
1