Induced pluripotent stem cells (iPSCs) may be obtained by direct reprogramming of different somatic cells to a pluripotent state by forced expression of a handful of transcription factors, These cells have similar properties to those of embryonic stem cells (escs) but bypass the ethical concerns of embryo destruction and can be exploited for both research and clinical applications.Discover the latest research on iPSC here.
Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.
Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.
Apoptotic caspases belong to the protease enzyme family and are known to play an essential role in inflammation and programmed cell death. Here is the latest research.
In autoimmune diseases, the immune system responds and attacks self-antigens and damages or impairs the function of the tissues. The treatment for autoimmune diseases often involves immunosuppressive agents, but newer treatments are being investigated. Discover the latest research on autoimmune disease therapy here.
Glioblastoma is the most common and aggressive type of brain tumor. It contains a population of tumor initiating stem cell-like cells known as cancer stem cells. Investigations are ongoing into these cancer stem cells found in these solid tumors which are highly resistance to treatment. Here is the latest research on cancer stem cells in glioblastoma.
Cardiac regeneration enables the repair of irreversibly damaged heart tissue using cutting-edge science, including stem cell and cell-free therapy. Discover the latest research on cardiac regeneration here.
mRNA-based technology is being studied as a potential technology that could be used to reprogram cell fate. This technique provides the potential to generate safe reprogrammed cells that can be used for clinical applications. Here is the latest research on cell fate conversion by mRNA.
Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins on cellular differentiation.
Cilia produce different signaling molecules including ciliary neurotrophic factor that modulate the expression of many processes throughout the body. Exploiting the signaling pathway may be a therapeutic strategy for promoting the growth of different cell types. Here is the latest research on ciliary signaling and growth.
Cis-regulatory elements are regions DNA that regulate the transcription of neighbouring genes. Trans-regulatory elements are genomic loci that regulate the expression of distant genes. Here is the latest research on CREs and TREs.