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Inflammasome and Pyroptosis

Inflammasome and Pyroptosis diagram by Haitao Guo, Wikimedia
Haitao Guo, Wikimedia

Pyroptosis is a form of necrotic and inflammatory programmed cell death induced by inflammatory caspases, one of which is activated by Inflammasome, a multiprotein oligomer responsible for the activation of inflammatory responses. Discover the latest research on inflammasome and pyroptosis here.

Top 20 most recent papers
May 23, 2020
ReviewOpen Access

Remodeling adipose tissue inflammasome for type 2 diabetes mellitus treatment: Current perspective and translational strategies

Bioengineering & Translational Medicine
Amrita Banerjee, Jagdish Singh
May 23, 2020

Danger-associated metabolic modifications during bacterial infection of macrophages

International Immunology
Mariatou DraméPedro Escoll
May 23, 2020
Open Access

The NLRP3-Mediated Neuroinflammatory Responses to CdTe Quantum Dots and the Protection of ZnS Shell

International Journal of Nanomedicine
Tianshu WuMeng Tang
May 20, 2020
ReviewOpen Access

Autoinflammatory Mechanisms in Crystal-Induced Arthritis

Frontiers in Medicine
Francesca OlivieroPaolo Sfriso
May 22, 2020

Design, synthesis, and screening of sulfonylurea-derived NLRP3 inflammasome inhibitors

Medicinal Chemistry Research : an International Journal for Rapid Communications on Design and Mechanisms of Action of Biologically Active Agents
Amol A KulkarniJ Phillip Bowen
May 21, 2020
ReviewOpen Access

Alveolar Dynamics and Beyond - The Importance of Surfactant Protein C and Cholesterol in Lung Homeostasis and Fibrosis

Frontiers in Physiology
Kirsten SehlmeyerElena Lopez-Rodriguez
May 25, 2020

Dopamine D1 receptor agonist A68930 attenuates acute kidney injury by inhibiting NLRP3 inflammasome activation

Journal of Pharmacological Sciences
Jing-Yuan CaoHong Liu
May 23, 2020

High glucose mediates NLRP3 inflammasome activation via upregulation of ELF3 expression

Cell Death & Disease
Jing WangChanghong Miao
May 24, 2020

ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome

Cancer Immunology Research
Melody CheongGeoffrey R Hill

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