Innate Immunity: Neurodegeneration

The innate immune system is a first line of defense against infection. Pathological states can occur if there is over activation of the innate immune system, particularly in the brain. The excessive activation of these cells can lead to inflammation and neurodegenerative diseases. Here is the latest research on innate immunity and neurodegeneration.

August 29, 2020

Enhancing mitophagy as a therapeutic approach for neurodegenerative diseases

International Review of Neurobiology
Yahyah AmanEvandro Fei Fang
October 18, 2020
Review
Open Access

Microglia in Alzheimer's Disease in the Context of Tau Pathology

Biomolecules
Juan Ramón PereaJesús Avila
July 29, 2020
Review
Open Access

SAMHD1 acts at stalled replication forks to prevent interferon induction

Comptes rendus biologies
F CoquelP Pasero
July 19, 2020
Open Access

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

Journal of Neuroinflammation
Michiyo IbaEliezer Masliah
September 29, 2020
Review
Open Access

Role of Toll Like Receptor 4 in Alzheimer's Disease

Frontiers in Immunology
Maria Calvo-RodriguezLucía Núñez
August 30, 2020
Review
Open Access

Implication of Aging Related Chronic Neuroinflammation on COVID-19 Pandemic

Journal of Personalized Medicine
Paola BossùGianfranco Spalletta
April 3, 2020
Open Access

Microglia and other myeloid cells in CNS health and disease

The Journal of Pharmacology and Experimental Therapeutics
Adithya GopinathWolfgang Streit
August 9, 2020
Review
Open Access

Increasing the Chemical Variety of Small-Molecule-Based TLR4 Modulators: An Overview

Frontiers in Immunology
Alessio Romerio, Francesco Peri
April 1, 2020
Preprint
Open Access

Decreased salivary lactoferrin levels are specific to Alzheimer’s disease

ResearchSquare
Marta González-SánchezEva Carro
April 23, 2020
Open Access

Microbial BMAA and the Pathway for Parkinson's Disease Neurodegeneration

Frontiers in Aging Neuroscience
Daniela Nunes-CostaNuno Empadinhas
August 11, 2020
Review
Open Access

Beyond Host Defense: Deregulation of Drosophila Immunity and Age-Dependent Neurodegeneration

Frontiers in Immunology
Srishti Arora, Petros Ligoxygakis
September 30, 2020

Endothelial C3a receptor mediates vascular inflammation and BBB permeability during aging

The Journal of Clinical Investigation
Nicholas E PropsonHui Zheng
June 2, 2020
Review
Open Access

The Long and the Short of PTEN in the Regulation of Mitophagy

Frontiers in Cell and Developmental Biology
Liming WangHan-Ming Shen
March 9, 2020
Preprint
Open Access

Inhibition of IL34 unveils tissue-selectivity and is sufficient to reduce microglial proliferation in chronic neurodegeneration

BioRxiv : the Preprint Server for Biology
Juliane ObstDiego Gomez-Nicola
September 24, 2020
Review
Open Access

Role of Microglia in Modulating Adult Neurogenesis in Health and Neurodegeneration

International Journal of Molecular Sciences
Mohammed Al-OnaiziAyman ElAli
October 7, 2020

Mitochondrial Quality Control and Restraining Innate Immunity

Annual Review of Cell and Developmental Biology
Andrew T Moehlman, Richard J Youle
July 16, 2020
Review
Open Access

The Use of Antimicrobial and Antiviral Drugs in Alzheimer's Disease

International Journal of Molecular Sciences
Umar H IqbalGiulio M Pasinetti
April 21, 2020
Review
Open Access

The impact of nutrition on COVID-19 susceptibility and long-term consequences

Brain, Behavior, and Immunity
Michael J Butler, Ruth M Barrientos

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