Innate Immunity & Neurodegeneration

The innate immune response is an important regulator of the downstream immune response, and it is becoming increasingly evident that immune dysfunction has impacts on the pathogenesis of multiple disease states, including neurodegeneration. Additionally, mutations in several genes involved in the innate immune response have been associated with neurodegeneration. Discover the latest research on innate immunity and neurodegeneration here.

December 7, 2021
Review

Microglial TREM2 in amyotrophic lateral sclerosis.

Developmental Neurobiology
Manling XieLong-Jun Wu
December 7, 2021
Review

Untangling senescent and damage-associated microglia in the aging and diseased brain.

The FEBS Journal
Pei Y NgDarren J Baker
December 7, 2021

Inflammation-dependent oxidative stress metabolites as a hallmark of amyotrophic lateral sclerosis.

Free Radical Biology & Medicine
Luyang XiongTatiana V Byzova
December 6, 2021
Open Access

Attractin Participates in Schizophrenia by Affecting Testosterone Levels.

Frontiers in Cell and Developmental Biology
Nan LiQingshun Zhao
December 6, 2021
Review

Vitamin D and its' role in Parkinson's disease patients with SARS-CoV-2 infection. A review article.

Interdisciplinary Neurosurgery : Advanced Techniques and Case Management
Ahmed Y AzzamMohammed A Azab
December 6, 2021
Open Access

Drug Repositioning For Allosteric Modulation of VIP and PACAP Receptors.

Frontiers in Endocrinology
Ingrid Langer, Dorota Latek
December 6, 2021
Open Access

Anti-Inflammatory and Anti-Oxidative Effects of AM404 in IL-1β-Stimulated SK-N-SH Neuroblastoma Cells.

Frontiers in Pharmacology
Matthias ApweilerBernd L Fiebich
December 6, 2021
Review
Open Access

Insights Into the Role of CSF1R in the Central Nervous System and Neurological Disorders.

Frontiers in Aging Neuroscience
Banglian HuHonghua Zheng
December 6, 2021
Review
Open Access

Role of G Protein-Coupled Receptors in Microglial Activation: Implication in Parkinson's Disease.

Frontiers in Aging Neuroscience
Chao GuMei Wang
December 6, 2021

[Research progress of cell pyroptosis in the mechanism and treatment of glaucoma].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
J R Cao, Z Z Dong
December 6, 2021

[Progress of researches on mechanisms of acupuncture in treatment of Parkinson's disease].

Zhen ci yan jiu = Acupuncture research
Xiao-Bei SunShao-Peng Liu
December 6, 2021

Alterations in T-Cell Transcription Factors and Cytokine Gene Expression in Late-Onset Alzheimer's Disease.

Journal of Alzheimer's Disease : JAD
Masoud NeshanGhasem Ahangari
December 6, 2021
Review

Local and remote interactions between macrophages and microglia in neurological conditions.

Current Opinion in Immunology
Séverine Boillée
December 4, 2021

Targeted therapy strategies for melanoma brain metastasis.

Neuro-oncology Advances
Chantal SaberianMichael A Davies
December 4, 2021
Preprint
Open Access

Microglia Mediate Early Corticostriatal Synapse Loss and Cognitive Dysfunction in Huntingtons Disease Through Complement-Dependent Mechanisms

BioRxiv : the Preprint Server for Biology
D. K. WiltonBeth stevens
December 3, 2021

Neuroinflammation in Huntington's disease: A starring role for astrocyte and microglia.

Current Neuropharmacology
Julieta SabaCarla Caruso
December 2, 2021
Review

Imaging neuroinflammation with TSPO: A new perspective on the cellular sources and subcellular localization.

Pharmacology & Therapeutics
Tomás R GuilarteDiana J Azzam

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