Integrin Signalling

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal transduction pathways that mediate cellular signals such as regulation of the cell cycle, organization of the intracellular cytoskeleton, and movement of new receptors to the cell membrane. Discover the latest research on integrin signalling here.

October 25, 2021

Role of integrins in the metastatic spread of high-grade serous ovarian cancer.

Archives of Gynecology and Obstetrics
Slavomir KrajnakMarco Johannes Battista
October 25, 2021

Effects of Platelet Agonists and Priming on the Formation of Platelet Populations.

Thrombosis and Haemostasis
Alicia VeningaPaola E J van der Meijden
October 26, 2021

Seeding metastases: The role and clinical utility of circulating tumour cells.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine
Deep A Patel, Jonathan Blay
October 26, 2021
Open Access

Evaluation of Natalizumab Pharmacokinetics and Pharmacodynamics: Toward Individualized Doses.

Frontiers in Neurology
Jose M Serra López-MatencioCecilia Muñoz-Calleja
October 26, 2021
Open Access

The PDAC Extracellular Matrix: A Review of the ECM Protein Composition, Tumor Cell Interaction, and Therapeutic Strategies.

Frontiers in Oncology
Vincent M PerezJen Jen Yeh
October 26, 2021

PET Imaging of VLA-4 in a New BRAFV600E Mouse Model of Melanoma.

Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging
Michael C BellaviaCarolyn J Anderson
October 26, 2021

Soluble Klotho-integrin β1/ERK1/2 pathway ameliorates myocardial fibrosis in diabetic cardiomyopathy.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Jia-Min LiWen-Yuan Ding
October 25, 2021
Open Access

Tension-driven multi-scale self-organisation in human iPSC-derived muscle fibers

BioRxiv : the Preprint Server for Biology
Q. MaoFrank Schnorrer
October 22, 2021

Cell adhesion suppresses autophagy via Src/FAK-mediated phosphorylation and inhibition of AMPK.

Cellular Signalling
Ming ZhaoKristiina Vuori
October 22, 2021

CD93 a potential player in cytotrophoblast and endothelial cell migration.

Cell and Tissue Research
Sonia FantoneDaniela Marzioni
October 22, 2021

Not one, but many forms of thrombosis proteins.

Journal of Thrombosis and Haemostasis : JTH
Aster PijningPhilip J Hogg

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