Integrin Signalling

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal transduction pathways that mediate cellular signals such as regulation of the cell cycle, organization of the intracellular cytoskeleton, and movement of new receptors to the cell membrane. Discover the latest research on integrin signalling here.

July 8, 2020
Open Access

Beneficial Effects of Soluble Guanylyl Cyclase Stimulation and Activation in Sickle Cell Disease are Amplified by Hydroxyurea: In Vitro and In Vivo Studies

The Journal of Pharmacology and Experimental Therapeutics
Wilson A FerreiraNicola Conran
July 6, 2020
Open Access

Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury

Tomohiro YokotaArjun Deb
July 8, 2020

Circulating Tumor Cell Migration Requires Fibronectin Acting through Integrin B1 or SLUG

Jeannette Huaman, Olorunseun O Ogunwobi
July 9, 2020
Open Access

Osteoclast Signal Transduction During Bone Metastasis Formation

Frontiers in Cell and Developmental Biology
Dávid S Győri, Attila Mócsai
July 7, 2020

No Benefit of Concomitant Immunomodulator Therapy on Efficacy of Biologics That are Not Tumor Necrosis Factor Antagonists in Patients With Inflammatory Bowel Diseases: a Meta-Analysis

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Clara YzetMathurin Fumery
July 10, 2020

Mural Cell-Specific Deletion of Cerebral Cavernous Malformation 3 in the Brain Induces Cerebral Cavernous Malformations

Arteriosclerosis, Thrombosis, and Vascular Biology
Kang WangHuanjiao Jenny Zhou
July 9, 2020

Clinical impact of urinary CD11b and CD163 on the renal outcomes of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Yuki YokoeSeiichi Matsuo
July 7, 2020

Design and screening of FAK, CDK 4/6 dual inhibitors by pharmacophore model, molecular docking, and molecular dynamics simulation

Journal of Biomolecular Structure & Dynamics
Chuance SunCongmin Kang
July 8, 2020
Open Access

Effects of DSPP and MMP20 Silencing on Adhesion, Metastasis, Angiogenesis, and Epithelial-Mesenchymal Transition Proteins in Oral Squamous Cell Carcinoma Cells

International Journal of Molecular Sciences
Jaya Aseervatham, Kalu U E Ogbureke
July 7, 2020
Open Access

Antimicrobial Resistance in Swine Fecal Specimens Across Different Farm Management Systems

Frontiers in Microbiology
Suporn PholwatSuporn Foongladda
July 9, 2020

Binding of acidic PLA2 Ba SPII RP4 from Bothrops alternatus snake venom to integrin αvβ3: An in silico study

Toxicon : Official Journal of the International Society on Toxinology
Emilio AngelinaLaura Cristina Leiva
July 10, 2020

Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis

ACS Applied Materials & Interfaces
Allison N Ramey-WardKhalid Salaita
July 9, 2020

Adenovirus Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification

ACS Applied Materials & Interfaces
Daniel FleischmannAchim Michael Goepferich
July 7, 2020
Open Access

Hydrogel Culture Surface Stiffness Modulates Mesenchymal Stromal Cell Secretome and Alters Senescence

Tissue Engineering. Part a
Molly E OgleJohnna S Temenoff

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