Integrin Signalling

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal transduction pathways that mediate cellular signals such as regulation of the cell cycle, organization of the intracellular cytoskeleton, and movement of new receptors to the cell membrane. Discover the latest research on integrin signalling here.

October 21, 2020

Zafirlukast is a broad-spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times

British Journal of Pharmacology
Lisa-Marie HolbrookDaniel R Kennedy
October 24, 2020
Open Access

Unannotated single nucleotide polymorphisms in the TATA box of erythropoiesis genes show in vitro positive involvements in cognitive and mental disorders

BMC Medical Genetics
Mikhail PonomarenkoLudmila Savinkova
October 21, 2020
Open Access

Integration of RNA-Seq and proteomics data identifies glioblastoma multiforme surfaceome signature

Saiful Effendi SyafruddinM. Aiman Mohtar
October 24, 2020
Open Access

Mechanoregulation in hematopoiesis and hematologic disorders

Current Stem Cell Reports
Paulina D HortonPamela L Wenzel
October 23, 2020
Open Access

Molecular Aspects of Thyroid Calcification

International Journal of Molecular Sciences
Luciana Bueno FerreiraPaula Soares
October 23, 2020

Sinus Irrigation Penetration After Proposed Modified Draf IIa Technique in a Side-to-Side Cadaveric Model

American Journal of Rhinology & Allergy
Khalil IssaRalph Abi Hachem
October 23, 2020
Open Access

Bidirectional Tumor-Promoting Activities of Macrophage Ezrin

International Journal of Molecular Sciences
Krishnendu KhanPaul L Fox
October 24, 2020

Mir-30d Regulates Cardiac Remodeling by Intracellular And Paracrine Signaling

Circulation Research
Jin LiSaumya Das
October 22, 2020

Extended storage of thawed platelets: Refrigeration supports postthaw quality for 10 days

Lacey JohnsonDenese C Marks
October 23, 2020

Peritoneal Spread of Ovarian Cancer harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling

Cancer Research
Deepak ParasharPradeep Chaluvally-Raghavan
October 23, 2020
Open Access

RAGE Up-Regulation Differently Affects Cell Proliferation and Migration in Pancreatic Cancer Cells

International Journal of Molecular Sciences
Priyanka SwamiEstelle Leclerc
October 25, 2020

Corrigendum to "The soluble nectin-4 ecto-domain promotes breast cancer induced angiogenesis via endothelial Integrin-β4" [Int J Biochem Cell Biol, 2018, Sep, 102, 151-160

The International Journal of Biochemistry & Cell Biology
Sumit SiddharthChanakya Nath Kundu
October 22, 2020

Thyroid hormones reduce nicotinic receptor mediated currents in SH-SY5Y neuroblastoma cells

Pharmacological Reports : PR
Giulia Puia, Federica Ravazzini

Sign up to follow this feed and discover related papers.

Related Feeds

Adherens Junctions

An adherens junction is defined as a cell junction whose cytoplasmic face is linked to the actin cytoskeleton. They can appear as bands encircling the cell (zonula adherens) or as spots of attachment to the extracellular matrix (adhesion plaques). Adherens junctions uniquely disassemble in uterine epithelial cells to allow the blastocyst to penetrate between epithelial cells. Discover the latest research on adherens junctions here.

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Basement Membranes

Basement membranes are thin, specialized extracellular matrices surrounding most tissues in all metazoans. Here is the latest research on basement membranes.

Biophysics of Adhesion

Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. It is also essential for infectious organisms, such as bacteria or viruses, to cause diseases. Understanding the biophysics of cell adhesion can help understand these diseases. Discover the latest research on the biophysics of adhesion here.

Cadherins and Catenins

Cadherins (named for "calcium-dependent adhesion") are a type of cell adhesion molecule (CAM) that is important in the formation of adherens junctions to bind cells with each other. Catenins are a family of proteins found in complexes with cadherin cell adhesion molecules of animal cells: alpha-catenin can bind to β-catenin and can also bind actin. β-catenin binds the cytoplasmic domain of some cadherins. Discover the latest research on cadherins and catenins here.

Cancer Cell Invasion: Nanomedicine

Nanomedicine is a promising alternative for cancer detection and therapy that utilizes nanoparticles, such as liposomes. Nanoparticles can potentially target cancer cell invasion and metastasis. Discover the latest research on Cancer Cell Invasion: Nanomedicine here.

Cell Adhesion Molecules in AS

Cell adhesion molecules expressed on the vascular endothelium and circulating leukocytes in response to inflammatory stimuli are implicated in atherosclerosis. Here is the latest research.

Cell Adhesion Molecules in the Brain

Cell adhesion molecules found on cell surface help cells bind with other cells or the extracellular matrix to maintain structure and function. Here is the latest research on their role in the brain.

Cell Migration in Cancer and Metastasis

Migration of cancer cells into surrounding tissue and the vasculature is an initial step in tumor metastasis. Discover the latest research on cell migration in cancer and metastasis here.


Chondrogenesis is the earliest phase of skeletal development, involving mesenchymal cell recruitment and migration, condensation of progenitors, and chondrocyte differentiation, and maturation and resulting in the formation of cartilage and bone during endochondral ossification. Here is the latest research.

© 2020 Meta ULC. All rights reserved