Integrins in Cancer Progression & Metastasis

The integrin family of cell adhesion receptors regulate diverse functions in cells and are implicated in the development, progression, and metastasis of solid tumors. Here is the latest research.

January 20, 2022

Lidocaine hampers colorectal cancer process via circITFG2/miR-1204/SOCS2 axis.

Anti-cancer Drugs
Huashe WangTing Pang
January 19, 2022
Open Access

Association between Arsenic Level, Gene Expression in Asian Population, and In Vitro Carcinogenic Bladder Tumor.

Oxidative Medicine and Cellular Longevity
Sonalika SinghalSandeep K Singhal
January 17, 2022

Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis.

Journal of Experimental & Clinical Cancer Research : CR
Jingjing ZhangWeiwei Feng
January 15, 2022
Open Access

Stem-like breast cancer cells in the activated state resist genetic stress via TGFBI-ZEB1.

NPJ Breast Cancer
Qi SunJay S Desgrosellier
January 15, 2022

TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer.

Cell Reports Medicine
Richard E BeatsonJohn Maher
January 14, 2022
Open Access

Collagen-binding integrin alpha11beta1 contributes to joint destruction in arthritic hTNFtg mice

BioRxiv : the Preprint Server for Biology
A. DeichselAdelheid Korb-Pap
January 15, 2022

Expression of tissue factor and TF-mediated integrin regulation in HTR-8/SVneo trophoblast cells.

Journal of Reproductive Immunology
Mallikarjun GundappaVelayuthaprabhu Shanmugam
January 14, 2022

Promotion of tumor progression by exosome transmission of circular RNA circSKA3.

Molecular Therapy. Nucleic Acids
William W DuBurton B Yang
January 13, 2022

LncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.

Molecular Therapy : the Journal of the American Society of Gene Therapy
Xingwen WangYing Hu
January 13, 2022
Open Access

Integrin/TGF-β1 inhibitor GLPG-0187 blocks SARS-CoV-2 Delta and Omicron pseudovirus infection of airway epithelial cells which could attenuate disease severity.

MedRxiv : the Preprint Server for Health Sciences
Kelsey E HuntingtonWafik El-Deiry
January 13, 2022

Smooth muscle mineralocorticoid receptor as an epigenetic regulator of vascular aging.

Cardiovascular Research
Jaime IbarrolaIris Z Jaffe
January 12, 2022
Open Access

Canonical Wnt Signaling Induces Focal Adhesion and Integrin Beta-1 Endocytosis

BioRxiv : the Preprint Server for Biology
Nydia Tejeda-MunozE. De Robertis

Sign up to follow this feed and discover related papers.

Related Feeds

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

Biophysics of Adhesion

Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. It is also essential for infectious organisms, such as bacteria or viruses, to cause diseases. Understanding the biophysics of cell adhesion can help understand these diseases. Discover the latest research on the biophysics of adhesion here.

Cancer Biology: Molecular Imaging

Molecular imaging enables noninvasive imaging of key molecules that are crucial to tumor biology. Discover the latest research in molecular imaging in cancer biology in this feed.

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Cell Migration in Cancer and Metastasis

Migration of cancer cells into surrounding tissue and the vasculature is an initial step in tumor metastasis. Discover the latest research on cell migration in cancer and metastasis here.

Cell Signaling by Tyrosine Kinases

Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. RTKs have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. Discover the latest research on cell signaling and RTK here.

Circadian Clock & Cancer

Circadian rhythms are natural, internal processes that regulate the sleep-wake cycle. Chronic disruptions in circadian rhythms have been associated with the development of a variety of diseases including cancer. Here is the latest research on circadian rhythms and cancer.

Circular RNAs in Cancer

Circular RNA (circRNA) are stable non-coding RNAs implicated in gene regulation, cell differentiation, tissue homeostasis, and tumorigenesis. Their role as a potential diagnostic and prognostic biomarker and as a possible therapeutic target is currently under investigation. Here is the latest research on circRNAs in cancer.

© 2022 Meta ULC. All rights reserved