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International Cancer Genome Consortium

International Cancer Genome Consortium diagram by Tartila, Shutterstock
Tartila, Shutterstock

The International Cancer Genome Consortium (ICGC) was founded with the goal of mapping the genome of 25,000 primary untreated cancers. The ICGC has also pushed for the global sharing of genomic data to facilitate cancer research. Find the latest research from the ICGC here.

Top 20 most recent papers
Nature Genetics

Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

Nature GeneticsJanuary 15, 2020
Michelle Chan-Seng-YueFaiyaz Notta
81
2
JAMA Oncology

Association Between 21-Gene Assay Recurrence Score and Locoregional Recurrence Rates in Patients With Node-Positive Breast Cancer

JAMA OncologyJanuary 10, 2020
Wendy A WoodwardKathy S Albain
75
5
2
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

Estrogen and Progesterone Receptor Testing in Breast Cancer: ASCO/CAP Guideline Update

Journal of Clinical Oncology : Official Journal of the American Society of Clinical OncologyJanuary 14, 2020
Kimberly H AllisonAntonio C Wolff
46
Archives of Pathology & Laboratory Medicine

Estrogen and Progesterone Receptor Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Guideline Update

Archives of Pathology & Laboratory MedicineJanuary 14, 2020
Kimberly H AllisonAntonio C Wolff
18
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Multifactorial deep learning reveals pan-cancer genomic tumor clusters with distinct immunogenomic landscape and response to immunotherapy

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchJanuary 9, 2020
Feng XieTian Xia
23
bioRxiv

Transient Commensal Clonal Interactions Can Drive Tumor Metastasis

bioRxivJanuary 16, 2020
Suha Naffar-Abu AmaraJoan S S. Brugge
bioRxiv

Revealing the impact of recurrent and rare structural variants in multiple myeloma

bioRxivDecember 19, 2019
Even H RustadFrancesco Maura
21
bioRxiv

Sampling artifacts in single-cell genomics cohort studies

bioRxivJanuary 15, 2020
Ramon Massoni-BadosaHolger Heyn
152
bioRxiv

Endogenization and excision of human herpesvirus 6 in human genomes

bioRxivDecember 26, 2019
Xiaoxi LiuYoichiro Kamatani
70
Nature Medicine

Big data is crucial to the early detection of cancer

Nature MedicineJanuary 15, 2020
Rebecca C Fitzgerald
33
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer

Afatinib for the Treatment of Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations: A Database of 693 Cases

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung CancerJanuary 14, 2020
James Chih-Hsin YangEdward S Kim
Hepatology : Official Journal of the American Association for the Study of Liver Diseases

Modulation of biliary cancer chemo-resistance through microRNA-mediated rewiring of the expansion of CD133+ cells

Hepatology : Official Journal of the American Association for the Study of Liver DiseasesDecember 28, 2019
Pietro CarotenutoChiara Braconi
Neurosurgical Focus

Introduction. Pediatric brain tumor

Neurosurgical FocusJanuary 3, 2020
Samuel CheshierSabine Mueller
1
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchJanuary 11, 2020
Christian BrieghelCarsten U Niemann
4
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Germline DNA Sequencing Reveals Novel Mutations Predictive of Overall Survival in a Cohort of Pancreatic Cancer Patients

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchDecember 25, 2019
Jennifer B GoldsteinDavid R Fogelman
6
Scientific Reports

The AHR pathway represses TGFβ-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma

Scientific ReportsJanuary 12, 2020
Nemanja SarićM Albert Basson
8
Cancer Science

MicroRNA-493-5p-mediated repression of the MYCN oncogene inhibits hepatic cancer cell growth and invasion

Cancer ScienceDecember 29, 2019
Ken YasukawaLuc Gailhouste
2
Physiological Research

Sex-dependent regulation of estrogen receptor beta in human colorectal cancer tissue and its relationship with clock genes and VEGF-A expression

Physiological ResearchJanuary 14, 2020
I HerichovaM Zeman
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc

Multiregion exome sequencing of ovarian immature teratomas reveals 2N near-diploid genomes, paucity of somatic mutations, and extensive allelic imbalances shared across mature, immature, and disseminated components

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, IncJanuary 9, 2020
Michael B HeskettRaymond J Cho
5
Gut

The study of Lynch syndrome in a special population reveals a strong founder effect and an unusual mutational mechanism in familial adenomatous polyposis

GutJanuary 12, 2020
Abdul K SirajKhawla S Al-Kuraya

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