International Cancer Genomics Consortium (ICGC)

The International Cancer Genomics Consortium (ICGC) was established to investigate the genomic changes present in many forms of cancer. Follow this feed to stay up to date on research from this institute.

May 10, 2020
Open Access

The landscape of chromothripsis across adult cancer types

Nature Communications
Natalia VoroninaAurélie Ernst
May 20, 2020

Cas9 activates the p53 pathway and selects for p53-inactivating mutations

Nature Genetics
Oana M EnacheUri Ben-David
April 29, 2020

Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors

Nature Medicine
Johanna TheruvathCrystal L Mackall
May 3, 2020
Open Access

DNA methylation of chronic lymphocytic leukemia with differential response to chemotherapy

Scientific Data
Deyan Yordanov YosifovDaniel Mertens
May 14, 2020
Review
Open Access

Oncogene-Addicted Non-Small-Cell Lung Cancer: Treatment Opportunities and Future Perspectives

Cancers
Miriam Grazia FerraraEmilio Bria
July 1, 2020
Open Access

EGFR C797S as a Resistance Mechanism of Lazertinib in Non-small Cell Lung Cancer with EGFR T790M Mutation

Cancer Research and Treatment : Official Journal of Korean Cancer Association
Sehhoon ParkMyung-Ju Ahn
April 10, 2020
Open Access

JSCO/ESMO/ASCO/JSMO/TOS: International expert consensus recommendations for tumour-agnostic treatments in patients with solid tumours with microsatellite instability or NTRK fusions

Annals of Oncology : Official Journal of the European Society for Medical Oncology
T YoshinoJ-Y Douillard
May 7, 2020
Comment / Editorial

Toward clinical understanding of aristolochic acid upper-tract urothelial carcinoma

Theranostics
Arnoud BootSteven G Rozen
May 1, 2020
Open Access

Coronavirus Disease 2019 (COVID-19) Information for Cardiologists - Systematic Literature Review and Additional Analysis

Circulation Journal : Official Journal of the Japanese Circulation Society
Tadafumi SugimotoKoichi Node
June 5, 2020

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

Nature
Mikołaj SłabickiBenjamin L Ebert
June 9, 2020

Articulating the sources for an African normative framework of healthcare: Ghana as a case study

Developing World Bioethics
Caesar A AtuireMichael Dunn
June 20, 2020

Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer

Cancer Cell
Luisa F Escobar-HoyosSteven D Leach
June 4, 2020

HHEX promotes myeloid transformation in cooperation with mutant ASXL1

Blood
Reina TakedaToshio Kitamura
May 5, 2020
Open Access

Netboost: Boosting-supported Network Analysis Improves High-Dimensional Omics Prediction in Acute Myeloid Leukemia and Huntington's Disease

IEEE/ACM Transactions on Computational Biology and Bioinformatics
Pascal SchlosserMartin Schumacher
June 20, 2020
Open Access

A Germline PALB2 Pathogenic Variant identified in a Pediatric High Grade Glioma

Cold Spring Harbor Molecular Case Studies
Yiming ZhongMarilyn M Li

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Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

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Signaling in Adult Neurogenesis

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Psychiatric Chronotherapy

Psychiatric Chronotherapy considers the circadian rhythm as a major factor for optimizing therapeutic efficacy of psychiatric interventions. Discover the latest research on Psychiatric Chronotherapy here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

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