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International Cancer Genomics Consortium (ICGC)

International Cancer Genomics Consortium (ICGC) diagram by

The International Cancer Genomics Consortium (ICGC) was established to investigate the genomic changes present in many forms of cancer. Follow this feed to stay up to date on research from this institute.

Top 20 most recent papers
Nature

The molecular landscape of ETMR at diagnosis and relapse

NatureDecember 6, 2019
Sander LamboMarcel Kool
76
1
1
3
Nature Medicine

Author Correction: Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers

Nature MedicineNovember 21, 2019
Aparna R ParikhRyan B Corcoran
3
The Lancet Oncology

Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial

The Lancet OncologyNovember 23, 2019
Daniel P PetrylakRANGE study investigators
44
2
Cell

Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer

CellNovember 16, 2019
Avnish KapoorRonald A DePinho
6
1
3
Nature Medicine

Author Correction: Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

Nature MedicineOctober 31, 2019
Andrew Maltez ThomasNicola Segata
5
Blood

Mosunetuzumab Induces Complete Remissions in Poor Prognosis Non-Hodgkin Lymphoma Patients, Including Those Who Are Resistant to or Relapsing After Chimeric Antigen Receptor T-Cell (CAR-T) Therapies, and Is Active in Treatment through Multiple Lines

BloodNovember 15, 2019
Stephen J SchusterLihua E Budde
4
1
3
Cancer Cell

Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

Cancer CellNovember 12, 2019
Amaury LerusteFranck Bourdeaut
88
1
25
bioRxiv

Multiplexed single-cell profiling of post-perturbation transcriptional responses to define cancer vulnerabilities and therapeutic mechanism of action

bioRxivDecember 8, 2019
James M McFarlandAviad Tsherniak
93
1
Nature Communications

Integrated exome and RNA sequencing of dedifferentiated liposarcoma

Nature CommunicationsDecember 14, 2019
Makoto HirataKoichi Matsuda
13
Nature Communications

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

Nature CommunicationsDecember 22, 2019
Joshua M DempsterFrancesco Iorio
103
5
Journal for Immunotherapy of Cancer

Perspectives in immunotherapy: meeting report from the "Immunotherapy Bridge 2018" (28-29 November, 2018, Naples, Italy)

Journal for Immunotherapy of CancerDecember 1, 2019
Paolo A AsciertoIgor Puzanov
9
JAMA Network Open

Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer

JAMA Network OpenOctober 28, 2019
Olena M VaskeDavid Haussler
46
8
1
22
Cancer Cell

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

Cancer CellOctober 22, 2019
Jamie N AnastasYang Shi
68
35
bioRxiv

Reference-free deconvolution of complex DNA methylation data – a detailed protocol

bioRxivNovember 24, 2019
Michael SchererPavlo Lutsik
33
bioRxiv

annoFuse: an R Package to annotate and prioritize putative oncogenic RNA fusions

bioRxivNovember 12, 2019
Krutika S. GaonkarJo Lynne Rokita
15
2
Scientific Reports

Circulating tumor DNA as a prognostic indicator in resectable pancreatic ductal adenocarcinoma: A systematic review and meta-analysis

Scientific ReportsNovember 20, 2019
Jee-Soo LeeYoung Kyung Lee
11
2
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)

DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)October 28, 2019
Raghav SundarPatrick Tan
3
6
Nature Communications

Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia

Nature CommunicationsOctober 28, 2019
Yasutaka HayashiToshio Kitamura
5
8
Molecular Oncology

Towards a Cancer Mission in Horizon Europe

Molecular OncologyNovember 1, 2019
Anton BernsJulio E Celis
5
1
2
Leukemia

Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment

LeukemiaNovember 29, 2019
Aurélie CayeDominique Bonnet
11

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