iPSC-derived Microglia in Neurodegeneration

Induced pluripotent stem cell-derived microglia have recently been developed and provide unlimited access to patient-derived material. These cells can be used to model and investigate mechanism that underlie neurodegenerative diseases. Here is the latest research.

August 3, 2020
Open Access

Neuroinflammation and histone H3 citrullination are increased in X-linked Dystonia Parkinsonism post-mortem prefrontal cortex

Neurobiology of Disease
Tiziana PetrozzielloGhazaleh Sadri-Vakili
May 28, 2020
Open Access

ASC-Exosomes Ameliorate the Disease Progression in SOD1(G93A) Murine Model Underlining Their Potential Therapeutic Use in Human ALS

International Journal of Molecular Sciences
Roberta BonafedeRaffaella Mariotti
July 8, 2020
Open Access

Protective Mechanisms Against DNA Replication Stress in the Nervous System

Clara Forrer Charlier, Rodrigo A P Martins
August 23, 2020
Open Access

Chronic stress induces formation of stress granules and pathological TDP-43 aggregates in human ALS fibroblasts and iPSC-motoneurons

Neurobiology of Disease
Antonia RattiClaudia Colombrita
August 22, 2020
Open Access

Potential Therapeutic Usage of Nanomedicine for Glaucoma Treatment

International Journal of Nanomedicine
Song KwonJong Yeon Lee
June 11, 2020
Open Access

The Role of Hematopoietic Cell Transplant in the Glycoprotein Diseases

Brianna M NaumchikTroy C Lund
July 10, 2020
Open Access

Understanding cause and effect in Alzheimer's pathophysiology: implications for clinical trials

Neuropathology and Applied Neurobiology
Delphine Boche, James A R Nicoll
June 17, 2020

Spinal Cord Injury Leads to Hippocampal Glial Alterations and Neural Stem Cell Inactivation

Cellular and Molecular Neurobiology
Ignacio JureFlorencia Labombarda
May 30, 2020

Therapeutic Effects of Melatonin-Treated Bone Marrow Mesenchymal Stem Cells (BMSC) in a Rat Model of Alzheimer's Disease

Journal of Chemical Neuroanatomy
Mahdi RamezaniZoleikha Golipoor
August 31, 2020
Open Access

Nrf2/Wnt resilience orchestrates rejuvenation of glia-neuron dialogue in Parkinson's disease

Redox Biology
Bianca Marchetti
September 2, 2020
Open Access

Cell Therapies under Clinical Trials and Polarized Cell Therapies in Pre-Clinical Studies to Treat Ischemic Stroke and Neurological Diseases: A Literature Review

International Journal of Molecular Sciences
Masahiro HatakeyamaMasato Kanazawa
June 27, 2020
Open Access

MAP/ERK Signaling in Developing Cognitive and Emotional Function and Its Effect on Pathological and Neurodegenerative Processes

International Journal of Molecular Sciences
Héctor Albert-GascóFrancisco E Olucha-Bordonau
September 3, 2020
Open Access

Activated iPSC-microglia from C9orf72 ALS/FTD patients exhibit endosomal-lysosomal dysfunction

BioRxiv : the Preprint Server for Biology
I. LorenziniRita Sattler
June 26, 2020
Open Access

The Role of P2X7 Receptor in Alzheimer's Disease

Frontiers in Molecular Neuroscience
Linda FrancistiováMiguel Díaz-Hernández
July 7, 2020
Open Access

Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington's Disease

Frontiers in Cellular Neuroscience
Anya KimManuel J Rodríguez
July 7, 2020

ALS, a cellular whodunit on motor neuron degeneration

Molecular and Cellular Neurosciences
Peter Karagiannis, Haruhisa Inoue
June 13, 2020
Open Access

In vitro Models of Neurodegenerative Diseases

Frontiers in Cell and Developmental Biology
Anna SlanziGabriela Constantin
August 28, 2020
Open Access

Is the Immunological Response a Bottleneck for Cell Therapy in Neurodegenerative Diseases?

Frontiers in Cellular Neuroscience
Cristina Salado-ManzanoJosep M Canals
July 28, 2020
Open Access

Adipose-Derived Stem Cells Reduce Lipopolysaccharide-Induced Myelin Degradation and Neuroinflammatory Responses of Glial Cells in Mice

Journal of Personalized Medicine
Kateryna YatsenkoOleg Tsupykov
July 3, 2020
Open Access

Exosome Circuitry During (De)(Re)Myelination of the Central Nervous System

Frontiers in Cell and Developmental Biology
Helena S DominguesFábio G Teixeira

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