iPSC Isogenic Models of Disease

Differences in genetic backgrounds pose a limitation to studying and inferring genetic mechanisms of diseases. These limitations can be overcome using induced pluripotent stem cell-derived isogenic models of diseases. Here is the latest research.

May 24, 2020
Open Access

Extra-telomeric impact of telomeres: Emerging molecular connections in pluripotency or stemness

The Journal of Biological Chemistry
Soujanya VinayagamurthyShantanu Chowdhury
May 6, 2020
Open Access

Analysis of Drug Effects on iPSC Cardiomyocytes with Machine Learning

Annals of Biomedical Engineering
Martti JuholaKatriina Aalto-Setälä
May 13, 2020
Open Access

Metabolic Dysregulation of the Lysophospholipid/autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274

Circulation. Genomic and Precision Medicine
Sven W MeckelmannValerie B O'Donnell
May 14, 2020
Case Report

Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson's Disease

The New England Journal of Medicine
Jeffrey S SchweitzerKwang-Soo Kim
May 6, 2020
Open Access

Induced Pluripotent Stem Cells: Reprogramming Platforms and Applications in Cell Replacement Therapy

BioResearch Open Access
Akram Al AbbarSyahril Abdullah
May 1, 2020
Open Access

A Strategy for Personalized Treatment of iPS-Retinal Immune Rejections Assessed in Cynomolgus Monkey Models

International Journal of Molecular Sciences
Shota FujiiMasayo Takahashi
May 16, 2020

Recent technological advancements in stem cell research for targeted therapeutics

Drug Delivery and Translational Research
Nilesh RaiVibhav Gautam
May 21, 2020

METTL1 limits differentiation and functioning of EPCs derived from human-induced pluripotent stem cells through a MAPK/ERK pathway

Biochemical and Biophysical Research Communications
Yujie DengBeixin Yu
May 21, 2020

In Vitro and In Vivo Interspecies Chimera Assay Using Early Pig Embryos

Cellular Reprogramming
Monika Nowak-ImialekHeiner Niemann

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