iPSC Isogenic Models of Disease

Differences in genetic backgrounds pose a limitation to studying and inferring genetic mechanisms of diseases. These limitations can be overcome using induced pluripotent stem cell-derived isogenic models of diseases. Here is the latest research.

July 17, 2020
Review
Open Access

When Stiffness Matters: Mechanosensing in Heart Development and Disease

Frontiers in Cell and Developmental Biology
Roberto GaetaniElisa Messina
July 23, 2020

Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes

Cell Reports
Dries A M FeyenMark Mercola
July 17, 2020
Open Access

HLA-Matched Allogeneic iPS Cells-Derived RPE Transplantation for Macular Degeneration

Journal of Clinical Medicine
Sunao SugitaMasayo Takahashi
July 27, 2020

Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells

Gene Therapy
Toshinobu NishimuraHiromitsu Nakauchi
July 28, 2020

Generation of pluripotent stem cells using somatic cell nuclear transfer and induced pluripotent somatic cells from African Green Monkeys

Stem Cells and Development
Young Gie ChungDonald Eugene Redmond
July 28, 2020

Human Leukocyte Antigen Class I Pseudo-Homozygous Mesenchymal Stem Cells Derived from Human Induced Pluripotent Stem Cells

Stem Cell Reviews and Reports
Daekee KwonKyung-Sun Kang
July 22, 2020
Review

Heart regeneration using pluripotent stem cells

Journal of cardiology
Shin KadotaYuji Shiba
July 30, 2020
Open Access

Expansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential

Cell Reports
Shin-Ichi MaeKenji Osafune
July 12, 2020
Preprint
Open Access

Wide phenotypic spectrum of human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations

BioRxiv : the Preprint Server for Biology
August 2, 2020

Establishment and characterization of two iPSC lines derived from healthy controls

Stem Cell Research
Achchhe PatelBarbara Corneo
July 26, 2020
Preprint
Open Access

Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction

BioRxiv : the Preprint Server for Biology
Siyeon RheeKristy Red-Horse
July 16, 2020

Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells

Cell Reports
Nayara C LeiteDouglas A Melton
July 9, 2020
Review
Open Access

Immune reaction and regulation in transplantation based on pluripotent stem cell technology

Inflammation and Regeneration
Ryo OtsukaKen-Ichiro Seino
July 28, 2020
Review
Open Access

Microglia: Agents of the CNS Pro-Inflammatory Response

Cells
José A Rodríguez-GómezMiguel A Burguillos
July 7, 2020

Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome-Associated Cardiomyopathy

Circulation
Ulrich HansesLukas Cyganek

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