iPSC Isogenic Models of Disease

Differences in genetic backgrounds pose a limitation to studying and inferring genetic mechanisms of diseases. These limitations can be overcome using induced pluripotent stem cell-derived isogenic models of diseases. Here is the latest research.

January 20, 2021
Review

CADASIL from Bench to Bedside: Disease Models and Novel Therapeutic Approaches

Molecular Neurobiology
Arianna Manini, Leonardo Pantoni
January 8, 2021
Review
Open Access

Possible NK cell-mediated immune responses against iPSC-derived cells in allogeneic transplantation settings

Inflammation and Regeneration
Kyoko Masuda, Hiroshi Kawamoto
January 20, 2021

Unraveling the genomic basis of congenital heart disease

The Journal of Clinical Investigation
Dawood Darbar
January 16, 2021

Advances in CNS organoids: a focus on organoid-based models for motor neuron disease

Tissue Engineering. Part C, Methods
Renata Vieira de SaJeroen Pasterkamp
December 31, 2020
Preprint
Open Access

ApoE4-carrying Human Astrocytes Oversupply Cholesterol into Neurons and Promote Aβ Generation

ResearchSquare
Se-In LeeJinsoo Seo
January 15, 2021
Open Access

Effects of Survival Motor Neuron Protein on Germ Cell Development in Mouse and Human

International Journal of Molecular Sciences
Wei-Fang ChangLi-Ying Sung
January 6, 2021

Combinatorial Strategies for Long-term Control of HIV Infection

AIDS Reviews
Daekee KwonKyung-Sun Kang
January 4, 2021
Open Access

Studying leukemia stem cell properties and vulnerabilities with human iPSCs

Stem Cell Research
Nikolaos Spyrou, Eirini P Papapetrou
January 5, 2021
Review
Open Access

Great Expectations: Induced pluripotent stem cell technologies in neurodevelopmental impairments

International Journal of Medical Sciences
Xue ZhangZhongtao Gai
January 3, 2021
Review

Stem cell-based models and therapies: a key approach into schizophrenia treatment

Cell and Tissue Banking
Bagher LarijaniBabak Arjmand

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