iPSC Models in Neurodegeneration

Induced pluripotent stem cell (iPSCs) models can be generated to study mechanisms involved in neurodegeneration. The iPSCs can be selectively differentiated into specific neurons such as dopaminergic neurons that are susceptible to neurodegeneration. Discover the latest research on iPSC models in neurodegeneration here.

August 29, 2020
Open Access

Mitochondrial and Peroxisomal Alterations Contribute to Energy Dysmetabolism in Riboflavin Transporter Deficiency

Oxidative Medicine and Cellular Longevity
Fiorella ColasuonnoSandra Moreno
July 28, 2020
Preprint
Open Access

Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism

BioRxiv : the Preprint Server for Biology
Fadi JacobG.-l. Ming
July 11, 2020
Open Access

Chromosome-level de novo assembly of the pig-tailed macaque genome using linked-read sequencing and HiC proximity scaffolding

GigaScience
Morteza RoodgarMichael P Snyder
August 12, 2020
Preprint
Open Access

Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m.3243A > G heteroplasmy in iPSC-derived neurons

BioRxiv : the Preprint Server for Biology
T. M. Klein GunnewiekNael M Nadif Kasri
August 23, 2020
Open Access

Chronic stress induces formation of stress granules and pathological TDP-43 aggregates in human ALS fibroblasts and iPSC-motoneurons

Neurobiology of Disease
Antonia RattiClaudia Colombrita
July 24, 2020
Preprint
Open Access

Beneficial contribution of iPSC-progeny to connexin 47 dynamics during demyelination-remyelination

BioRxiv : the Preprint Server for Biology
Sabah MozafariA. Baron-Van Evercooren
September 1, 2020
Open Access

Applicability of hiPSC-derived neuronal co-cultures and rodent primary cortical cultures for in vitro seizure liability assessment

Toxicological Sciences : an Official Journal of the Society of Toxicology
Anke M TukkerRemco H S Westerink
August 28, 2020
Review
Open Access

Stem Cells of the Aging Brain

Frontiers in Aging Neuroscience
Alexandra M NicaiseStefano Pluchino
July 7, 2020
Open Access

Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington's Disease

Frontiers in Cellular Neuroscience
Anya KimManuel J Rodríguez
August 28, 2020
Review
Open Access

Is the Immunological Response a Bottleneck for Cell Therapy in Neurodegenerative Diseases?

Frontiers in Cellular Neuroscience
Cristina Salado-ManzanoJosep M Canals
July 28, 2020
Open Access

Adipose-Derived Stem Cells Reduce Lipopolysaccharide-Induced Myelin Degradation and Neuroinflammatory Responses of Glial Cells in Mice

Journal of Personalized Medicine
Kateryna YatsenkoOleg Tsupykov
September 2, 2020

Stem Cells: In Sickness and in Health

Current Stem Cell Research & Therapy
Hisham F BahmadWassim Abou-Kheir
August 26, 2020

Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis

Molecular Psychiatry
Thalita FigueiredoMayana Zatz
September 8, 2020
Preprint
Open Access

Highly enriched hiPSC-derived midbrain dopaminergic neurons robustly models Parkinson's disease.

BioRxiv : the Preprint Server for Biology
G. S. VirdiSonia Gandhi
September 12, 2020

DNA Methylation as a Potential Molecular Mechanism in X-Linked Dystonia-Parkinsonism

Movement Disorders : Official Journal of the Movement Disorder Society
Christin KrauseHenriette Kirchner
August 23, 2020
Open Access

Carbon Fibers as a New Type of Scaffold for Midbrain Organoid Development

International Journal of Molecular Sciences
Anna TejchmanMarcin Majka

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