iPSCs & type 1 diabetes

Insulin-producing cells derived from human embryonic stem cells or induced pluripotent stem cells have for long been a promising, but elusive treatment far from clinical translation into type 1 diabetes therapy. Here is the latest research.

July 22, 2020
Open Access

Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress

The Journal of Biological Chemistry
Xinlei YaoYuxin Li
July 18, 2020

Stem Cells: A Golden Therapy for Diabetic Wound

Current Diabetes Reviews
Shubhangi BuchadeKetki Rode
July 24, 2020

CPA1 and REG1a as New Markers for Pancreatic Acinar Cell Carcinoma

Human Pathology
Samar SaidTsung-Teh Wu
July 15, 2020
Open Access

Umbilical Cord-Mesenchymal Stem Cell-Conditioned Medium Improves Insulin Resistance in C2C12 Cell

Diabetes & Metabolism Journal
Kyung Soo KimYong Wook Cho
July 30, 2020

Brain insulin resistance impairs hippocampal plasticity

Vitamins and Hormones
Matteo SpinelliClaudio Grassi
July 16, 2020
Open Access

Mechanisms behind the Immunoregulatory Dialogue between Mesenchymal Stem Cells and Th17 Cells

Claudia Terraza-AguirreFarida Djouad
July 14, 2020

Acute murine cytomegalovirus disrupts established transplantation tolerance and causes recipient allo-sensitization

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Shuangjin YuXunrong Luo
July 21, 2020

Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology
Li QinDaniel J Müller
July 19, 2020
Open Access

Adipose stem cells from type 2 diabetic mice exhibit therapeutic potential in wound healing

Stem Cell Research & Therapy
Yongfa SunXiao Dong
August 4, 2020
Open Access

miR-205 regulates bone turnover in elderly female patients with type 2 diabetes mellitus through targeted inhibition of Runx2

Experimental and Therapeutic Medicine
Guangfeng ZhangXiaobing Li
August 1, 2020
Open Access

Large-Scale Expansion of Human Mesenchymal Stem Cells

Stem Cells International
Muhammad Najib Fathi Bin HassanJia Xian Law
July 16, 2020
Open Access

Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells

Cell Reports
Nayara C LeiteDouglas A Melton
July 28, 2020

β-Cell specific transcription factors in the context of diabetes mellitus and β-cell regeneration

Mechanisms of Development
Sivasangari BalakrishnanChidambaram Prahalathan
July 28, 2020

Pharmacological activation of Nrf2 promotes wound healing

European Journal of Pharmacology
Paul VictorKunka Mohanram Ramkumar
August 9, 2020

Distinct infrastructure of lipid networks in visceral and subcutaneous adipose tissues in overweight humans

The American Journal of Clinical Nutrition
Anish ZachariaArieh Moussaieff

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