JAK/STAT & Metabolism
The JAK/STAT signaling pathways is important for various processes including immunity, cell division, cell death, and tumor formation. Recent data has implicated this pathway in metabolic diseases including type 2 diabetes and obesity. Here is the latest research.
Functional conservation and divergence of duplicated the suppressor of cytokine signaling 1 in blunt snout bream (Megalobrama amblycephala)
Involvement of fat mass and obesity gene (FTO) in the anti-obesity action of Annona muricata Annonaceae: in silico and in vivo studies
Amyloid beta peptide is an endogenous negative allosteric modulator of leptin receptor
Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling
Zinc ions increase GH signaling ability through regulation of available plasma membrane-localized GHR
JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms
The JAK/STAT Pathway in Skeletal Muscle Pathophysiology
Bromodomain and Extraterminal Inhibition by JQ1 Produces Divergent Transcriptional Regulation of Suppressors of Cytokine Signaling Genes in Adipocytes
In Vitro Effects of Vaspin on Porcine Granulosa Cell Proliferation, Cell Cycle Progression, and Apoptosis by Activation of GRP78 Receptor and Several Kinase Signaling Pathways Including MAP3/1, AKT, and STAT3
STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue
PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy
Dynamics of body mass index and visceral adiposity index in patients with rheumatoid arthritis treated with tofacitinib
Bioinformatics analysis and genetic polymorphisms in genomic region of the bovine SH2B2 gene and their associations with molecular breeding for body size traits in qinchuan beef cattle
Relationship between serum 25-hydroxyvitamin D3 levels and severity of chronic periodontitis in type 2 diabetic patients: A cross-sectional study
Biological Effects of Ciliary Neurotrophic Factor on hMADS Adipocytes
Vaspin in the pig ovarian follicles: expression and regulation by different hormones
Soft drugs for dermatological applications: recent trends
Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics
JAK3 inhibitor-based immunosuppression in allogeneic islet transplantation in cynomolgus monkeys
Green Tea Polyphenol (-)-Epigallocatechin Gallate (EGCG) Attenuates Neuroinflammation in Palmitic Acid-Stimulated BV-2 Microglia and High-Fat Diet-Induced Obese Mice
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