JAK/STAT & Metabolism

The JAK/STAT signaling pathways is important for various processes including immunity, cell division, cell death, and tumor formation. Recent data has implicated this pathway in metabolic diseases including type 2 diabetes and obesity. Here is the latest research.

May 19, 2020

Involvement of fat mass and obesity gene (FTO) in the anti-obesity action of Annona muricata Annonaceae: in silico and in vivo studies

Journal of Diabetes and Metabolic Disorders
Olusola Olalekan ElekofehintiCourage Dele Famusiwa
April 27, 2020

Amyloid beta peptide is an endogenous negative allosteric modulator of leptin receptor

Neuroendocrinology
Erika CeconRalf Jockers
June 8, 2019

Zinc ions increase GH signaling ability through regulation of available plasma membrane-localized GHR

Journal of Cellular Physiology
Ruonan LiHainan Lan
May 23, 2019
ReviewOpen Access

The JAK/STAT Pathway in Skeletal Muscle Pathophysiology

Frontiers in Physiology
Viviana MoresiLibera Berghella
May 31, 2020

STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue

Molecular Metabolism
Doris KalteneckerRichard Moriggl
April 8, 2019
Open Access

PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy

Journal of Cellular and Molecular Medicine
Ya LiMing Zhong
November 30, 2019
Open Access

Biological Effects of Ciliary Neurotrophic Factor on hMADS Adipocytes

Frontiers in Endocrinology
Jessica PeruginiAntonio Giordano
May 8, 2019

Vaspin in the pig ovarian follicles: expression and regulation by different hormones

Reproduction : the Official Journal of the Society for the Study of Fertility
Patrycja KurowskaAgnieszka Rak
September 9, 2019
Review

Soft drugs for dermatological applications: recent trends

Drug Discovery Today
Silvio AprileTracey Pirali
April 2, 2020
Open Access

Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics

Diabetes/metabolism Research and Reviews
Ernesto Maddaloni, Raffaella Buzzetti

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