JAK/STAT & Metabolism

The JAK/STAT signaling pathways is important for various processes including immunity, cell division, cell death, and tumor formation. Recent data has implicated this pathway in metabolic diseases including type 2 diabetes and obesity. Here is the latest research.

September 7, 2020
Open Access

Biological Network Model of Effect of Chronic Intermittent Hypoxia on Spermatogenesis in Rats

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Jisheng WangBin Wang
September 28, 2020

Effects of aerobic exercise and resveratrol on the expressions of JAK2 and TGF-β1 in renal tissue of type 2 diabetes rats

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
Xiao Juan SunWei Li Jiang
August 18, 2020

Novel therapeutic agents for the treatment of diabetic kidney disease

Expert Opinion on Investigational Drugs
Rachel E HartmanSusan J Lewis
October 14, 2020

Targeting Drugs Against Fibroblast Growth Factor(s)-Induced Cell Signaling

Current Drug Targets
Shilpi AgrawalThallapuranam Krishnaswamy Suresh Kumar
November 13, 2020
Open Access

Examining the Frequency of the JAK2 (V617F) Mutation in Patients with Myeloproliferative Diseases in North Eastern Iran and the Effect of Treatment Intervention

Reports of Biochemistry & Molecular Biology
Mojila NasseriMohammad Reza Abbaszadegan
January 13, 2021
Open Access

Growth Hormone Signaling Pathway Leading to the Induction of DNA Synthesis and Proliferation in Primary Cultured Hepatocytes of Adult Rats

Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society for Pharmaceutical Sciences, Société Canadienne Des Sciences Pharmaceutiques
Mitsutoshi KimuraMasahiko Ogihara
January 16, 2021

Aberrant type 1 immunity drives susceptibility to mucosal fungal infections

Timothy J BreakMichail S Lionakis
November 28, 2020

Circadian clock disruption attenuated growth hormone(GH)-mediated signalling

General and Comparative Endocrinology
Xintong LyuLan Wu
October 7, 2020
Open Access

The Relationship between Leptin, the Leptin Receptor and FGFR1 in Primary Human Breast Tumors

Wyatt Boothby-ShoemakerJamie J Bernard
October 4, 2020

Ocular surface diabetic disease: A neurogenic condition?

The Ocular Surface
Antonio Di ZazzoStefano Bonini
October 27, 2020
Open Access

JAK Inhibitors Suppress Cancer Cachexia-Associated Anorexia and Adipose Wasting in Mice

JCSM Rapid Communications
Gurpreet AroraRodney Infante
November 17, 2020
Open Access

Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice

Cellular and Molecular Gastroenterology and Hepatology
Kyo SasakiKeisuke Hino
September 5, 2020
Open Access

Extramyocellular interleukin-6 influences skeletal muscle mitochondrial physiology through canonical JAK/STAT signaling pathways

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Hinnah AbidIan R Lanza
December 19, 2020

Chronic exposure to methylmercury enhances the anorexigenic effects of leptin in C57BL/6J male mice

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
Beatriz FerrerMichael Aschner

Sign up to follow this feed and discover related papers.

Related Feeds

AKT Pathway

This feed focuses on the AKT serine/threonine kinase, which is an important signaling pathway involved in processes such as glucose metabolism and cell survival.

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.

Advanced Imaging of Cellular Signaling

Cell signaling is a vital mechanism for communication within cells and outside with the environment. Several different signaling pathways have been found and advanced imaging techniques are being developed to visualize the molecules involved in these signaling pathways. Find the latest research in advanced imaging of cellular signaling here.

Aging & Diabetes

This feed focuses on the role of the aging process on developing diabetes.

Antidiabetic Cellular Plasticity

This feed focuses on mechanisms that underlie cellular plasticity as a treatment for diabetes and other degenerative diseases.

ApoE Phenotypes

Apolipoprotein E (APOE) is a protein involved in fat metabolism and associated with the pathogenesis of Alzheimer's disease and cardiovascular disease. Here is the latest research on APOE phenotypes.

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.


Asprosin is a fasting-induced hormone produced in the white adipose tissue to stimulate the hepatic release of glucose into the bloodstream. Discover the latest research on this protein hormone here.

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.

Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

© 2021 Meta ULC. All rights reserved