KEAP1-NRF2 in Cancer

NRF2 is primarily regulated by KEAP1 and is implicated in protecting cancer cells from chemotherapy and plays a role in cancer progression. Here is the latest research on KEAP1-NRF2 signal transduction pathway.

January 16, 2022

Proportion of B cell subsets and Nrf2 mediated redox regulation in systemic lupus erythematosus patients.

Immunobiology
Preeti GautamArchana Bhatnagar
January 16, 2022

Oncogenic E3 ubiquitin ligase NEDD4 binds to KLF8 and regulates the microRNA-132/NRF2 axis in bladder cancer.

Experimental & Molecular Medicine
Minghuan MaoHangyu Li
January 15, 2022

Perillyl alcohol attenuates rheumatoid arthritis via regulating TLR4/NF-κB and Keap1/Nrf2 signaling pathways: A comprehensive study onin-vitro and in-vivo experimental models.

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
Eswara Rao PuppalaV G M Naidu
January 14, 2022

Salidroside prevents PM2.5-induced BEAS-2B cell apoptosis via SIRT1-dependent regulation of ROS and mitochondrial function.

Ecotoxicology and Environmental Safety
Hui ShanWanwei Li
January 14, 2022

Loricrin and NRF2 Coordinate Cornification.

JID Innovations
Yosuke IshitsukaAkemi Ishida-Yamamoto
January 12, 2022
Review

Nrf2 Regulation by Curcumin: Molecular Aspects for Therapeutic Prospects.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Seyed Hossein ShahcheraghiLuciano Saso
January 10, 2022

Fatty acid binding protein 4 regulates pancreatic cancer cell proliferation via activation of nuclear factor E2-related factor 2.

Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery
Keith WirthMasato Yamamoto
January 7, 2022

SPOP mutations promote p62/SQSTM1-dependent autophagy and Nrf2 activation in prostate cancer.

Cell Death and Differentiation
Qing ShiChenji Wang
December 31, 2021
Review

Nrf2 and Oxidative Stress in liver Ischemia/Reperfusion Injury.

The FEBS Journal
Raquel G BardalloTeresa Carbonell
December 31, 2021

An aging-related signature predicts favorable outcome and immunogenicity in lung adenocarcinoma.

Cancer Science
Wenjing ZhangQinghua Wang
December 30, 2021

Ultrasound-Controlled CRISPR/Cas9 System Augments Sonodynamic Therapy of Hepatocellular Carcinoma.

ACS Central Science
Haohao YinHuixiong Xu

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