Kennedy Disease

Kennedy Disease, also known as X-linked bulbospinal muscular atrophy, is a progressive neuromuscular disorder caused by mutations in the androgen receptor gene and characterize by wasting of proximal and bulbar muscles. Here is the latest research.

September 7, 2019
Open Access

241st ENMC international workshop: Towards a European unifying lab for Kennedy's disease. 15-17th February, 2019 Hoofddorp, The Netherlands

Neuromuscular Disorders : NMD
Linda GreensmithEuropean SBMA Consortium
March 20, 2019
Open Access

Muscle contractility in spinobulbar muscular atrophy

Scientific Reports
Julia R DahlqvistJohn Vissing
November 20, 2019

Monozygotic Twins Discordant for Kennedy Disease: A Case Report

Journal of Clinical Neuromuscular Disease
Cyprian Popescu
April 12, 2020
Open Access

The French national protocol for Kennedy's disease (SBMA): consensus diagnostic and management recommendations

Orphanet Journal of Rare Diseases
Pierre-François PradatFrench Kennedy’s Disease Writing Group
December 27, 2019

The Role of Mutant RNA in the Pathogenesis of Huntington's Disease and Other Polyglutamine Diseases

Molekuliarnaia biologiia
A N BogomazovaM A Lagarkova
August 9, 2019
Open Access

Skeletal muscle MRI differentiates SBMA and ALS and correlates with disease severity

Neurology
Uros KlickovicPietro Fratta
June 27, 2020
Open Access

Efficacy of Botulinum Toxin for Treating Sialorrhea in Neuromuscular Conditions

Frontiers in Neurology
Harsh SinghRaghav Govindarajan
June 10, 2020
Review
Open Access

Cell-Clearing Systems Bridging Repeat Expansion Proteotoxicity and Neuromuscular Junction Alterations in ALS and SBMA

International Journal of Molecular Sciences
Fiona LimanaqiFrancesco Fornai
July 17, 2020

Autophagy and Polyglutamine Disease

Advances in Experimental Medicine and Biology
Haigang RenGuanghui Wang
May 18, 2019
Comment / Editorial
Open Access

Treatment of Prostate Cancers and Kennedy's Disease by PROTAC-Androgen Receptor Degradation

ACS Medicinal Chemistry Letters
Robert B Kargbo
July 31, 2020

Myoglobin: A new biomarker for spinal and bulbar muscular atrophy?

The International Journal of Neuroscience
Haixiao GuoXiaolu Liu
March 30, 2019
Open Access

Brain MRI shows white matter sparing in Kennedy's disease and slow-progressing lower motor neuron disease

Human Brain Mapping
Edoardo G SpinelliMassimo Filippi
April 21, 2019
Clinical Trial

High-intensity training in patients with spinal and bulbar muscular atrophy

Journal of Neurology
Karen HejeJohn Vissing
May 12, 2020

BDNF as a novel therapeutic candidate for Kennedy's disease

The Journal of Physiology
Takashi Yokota
June 13, 2020
Open Access

Sonic Hedgehog-Gli1 Signaling and Cellular Retinoic Acid Binding Protein 1 Gene Regulation in Motor Neuron Differentiation and Diseases

International Journal of Molecular Sciences
Yu-Lung LinLi-Na Wei
August 11, 2020

Molecular pathogenesis of spinal bulbar muscular atrophy (Kennedy's disease) and avenues for treatment

Current Opinion in Neurology
Christopher Grunseich, Kenneth H Fischbeck

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