Killing Mechanisms

Cytolytic t lymphocytes exert two main specific molecular killing mechanisms against target cells, namely (i) they can synthesize and release soluble cytolytic factors, and (ii) they can express effector molecules that act as ligands of receptors expressed by target cells on the cell surface. Here is the latest research on killing mechanisms.

January 16, 2021
Open Access

Enhanced Expression of miR-181b in B Cells of CLL Improves the Anti-Tumor Cytotoxic T Cell Response

Mirco Di MarcoRosa Visone
January 15, 2021
Open Access

α-Pinene Enhances the Anticancer Activity of Natural Killer Cells via ERK/AKT Pathway

International Journal of Molecular Sciences
Hantae JoMi-Gi Lee
January 17, 2021

Nanodrug with dual-sensitivity to tumor microenvironment for immuno-sonodynamic anti-cancer therapy

Jinsheng HuangXintao Shuai
January 20, 2021

Investigation on the biological activity of anthocyanins and polyphenols in blueberry

Journal of Food Science
Sen YangXiaohong Kou
January 20, 2021

Blocking IL-17A enhances tumor response to anti-PD-1 immunotherapy in microsatellite stable colorectal cancer

Journal for Immunotherapy of Cancer
Chao LiuYanqiao Zhang
January 17, 2021
Case Report

Idiopathic CD4 T Cell Lymphocytopenia: A Case of Overexpression of PD-1/PDL-1 and CTLA-4

Infectious Disease Reports
Gaurav KumarPierre-Marie Roger
January 16, 2021
Open Access

Commentary on 'Autophagy promotes phagocytosis and clearance of Treponema pallidum via the NLRP3 inflammasome in macrophages'

Journal of the European Academy of Dermatology and Venereology : JEADV
N H Brockmeyer
January 16, 2021
Open Access

Disruption of gastric mucous granule exocytosis by Helicobacter pylori virulence factor CagA

Ryo NinomiyaFumihiko Hamada
January 17, 2021

Perforin and granzymes in neurological infections: From humans to cattle

Comparative Immunology, Microbiology and Infectious Diseases
Lucía Martínez Cuesta, Sandra Elizabeth Pérez
January 17, 2021

Gold digging: Searching for gut microbiota that enhances antitumor immunity

Journal of Cellular Physiology
Fengyi HouYujing Bi
January 16, 2021

Targeting Cancer Heterogeneity with Immune Responses Driven by Oncolytic Peptides

Trends in Cancer
Ilio VitaleLorenzo Galluzzi
January 17, 2021

PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques

Science Immunology
Keith D KauffmanDaniel L Barber
January 15, 2021
Open Access

Therapy of lymphoma by immune checkpoint inhibitors: the role of T cells, NK cells and cytokine-induced tumor senescence

Journal for Immunotherapy of Cancer
Fatima AhmetlicRalph Mocikat

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