Lennox-Gastaut Syndrome

Lennox-Gastaut syndrome is a rare epileptic syndrome characterized by multiple types of seizures, developmental delay, and cognitive impairment. It can be caused by trauma, infections, metabolic disorders, or genetic factors. Find the latest research on Lennox-Gastaut syndrome here.

August 30, 2020
Open Access

Centromedian thalamic responsive neurostimulation for Lennox-Gastaut epilepsy and autism

Annals of Clinical and Translational Neurology
Churl-Su KwonSaadi Ghatan
September 11, 2020

Cannabidiol inhibits multiple cardiac ion channels and shortens ventricular action potential duration in vitro

European Journal of Pharmacology
Marguerite Le MaroisGeorg Andrees Bohme
September 10, 2020
Open Access

Slow Titration of Cannabidiol Add-On in Drug-Resistant Epilepsies Can Improve Safety With Maintained Efficacy in an Open-Label Study

Frontiers in Neurology
Gianluca D'OnofrioRima Nabbout
May 14, 2020

Stereotactic laser anterior corpus callosotomy for Lennox-Gastaut syndrome

Epilepsia
James X TaoPeter C Warnke
June 22, 2020
Review
Open Access

Expert opinion: Proposed diagnostic and treatment algorithms for Lennox-Gastaut syndrome in adult patients

Epilepsy & Behavior : E&B
Georgia MontourisSteve Chung
August 1, 2020

De novo CACNA1G variants in developmental delay and early-onset epileptic encephalopathies

Journal of the Neurological Sciences
Misako KuniiFumiaki Tanaka
May 1, 2020
Open Access

RNAi-Based Gene Therapy Rescues Developmental and Epileptic Encephalopathy in a Genetic Mouse Model

Molecular Therapy : the Journal of the American Society of Gene Therapy
Osasumwen V AimiuwuWayne N Frankel
June 17, 2020

Improving the dissolution of a water-insoluble orphan drug through a fused deposition modelling 3-Dimensional printing technology approach

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
Mehtap Saydam, Sevgi Takka
July 14, 2020
Open Access

Medical cannabis: What practitioners need to know

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
R Van RensburgE H Decloedt
August 8, 2020

Nonseizure consequences of Dravet syndrome, KCNQ2-DEE, KCNB1-DEE, Lennox-Gastaut syndrome, ESES: A functional framework

Epilepsy & Behavior : E&B
Anne T BergGerry Nesbitt
May 30, 2020
Open Access

GABAA receptor β3 subunit mutation D120N causes Lennox-Gastaut syndrome in knock-in mice

Brain Communications
Shimian QuRobert L Macdonald
July 3, 2020

Thrombocytopenia in pediatric patients on concurrent cannabidiol and valproic acid

Epilepsia
Nancy A McNamaraRenée A Shellhaas
August 26, 2020
Review
Open Access

Emerging Use of Epidiolex (Cannabidiol) in Epilepsy

The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG
Renad Abu-SawwaYong Park
July 14, 2020
Review
Open Access

The Impact of Cannabidiol on Psychiatric and Medical Conditions

Journal of Clinical Medicine Research
Thersilla Oberbarnscheidt, Norman S Miller
July 28, 2020

Cost-Effectiveness of Cannabidiol Adjunct Therapy versus Usual Care for the Treatment of Seizures in Lennox-Gastaut Syndrome

PharmacoEconomics
Edward E NeubergerDavid L Veenstra
September 16, 2020

Boricua Founder Variant in FRRS1L Causes Epileptic Encephalopathy With Hyperkinetic Movements

Journal of Child Neurology
Imane AbdelmoumenMichael C Schneider
June 20, 2020
Review

Current application of cannabidiol (CBD) in the management and treatment of neurological disorders

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Brian FianiSyed A Quadri
June 6, 2020

Intranasal delivery of topiramate nanoemulsion: Pharmacodynamic, pharmacokinetic and brain uptake studies

International Journal of Pharmaceutics
Ravish J Patel, Rajesh H Parikh

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