Lennox-Gastaut Syndrome

Lennox-Gastaut syndrome is a rare epileptic syndrome characterized by multiple types of seizures, developmental delay, and cognitive impairment. It can be caused by trauma, infections, metabolic disorders, or genetic factors. Find the latest research on Lennox-Gastaut syndrome here.

September 13, 2021

Safety and efficacy of rufinamide in children and adults with Lennox-Gastaut syndrome: A post hoc analysis from Study 022.

Epilepsy & Behavior : E&B
Alexis ArzimanoglouManoj Malhotra
September 9, 2021
Review

Cannabidiol modulation of oxidative stress and signalling.

Neuronal Signaling
Sónia R PereiraEric J Downer
September 6, 2021
Review

Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain.

Revista de neurologia
J J García-PeñasV Villanueva-Haba
August 27, 2021
Review
Open Access

An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies.

International Journal of Molecular Sciences
Parthena MartinBradley S Galer
August 21, 2021
Review

Pharmacotherapy for Seizures in Tuberous Sclerosis Complex.

CNS Drugs
Rima NabboutPaolo Curatolo
August 21, 2021

Cluster analysis of a large dataset of patients with Lennox-Gastaut syndrome.

Seizure : the Journal of the British Epilepsy Association
Ali A Asadi-PooyaMohsen Farazdaghi
August 17, 2021

Improved Bioavailability with Dry Powder Cannabidiol Inhalation: A Phase 1 Clinical Study.

Journal of Pharmaceutical Sciences
Orrin DevinskyAndrea Leone-Bay
August 14, 2021

Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H).

Journal of Medicinal Chemistry
Tatsuki KoikeTakanobu Kuroita
August 11, 2021

The impact of seizure frequency on quality of life in patients with Lennox-Gastaut syndrome or Dravet syndrome.

Epilepsy & Behavior : E&B
Stéphane AuvinAndrew Saich
August 6, 2021
Review
Open Access

Epilepsy Syndromes in the First Year of Life and Usefulness of Genetic Testing for Precision Therapy.

Genes
Allan BayatRikke S Møller
July 31, 2021
Open Access

Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol.

Drug Metabolism and Disposition : the Biological Fate of Chemicals
Jessica L BeersKlarissa D Jackson
July 29, 2021

Children With Trisomy 21 and Lennox-Gastaut Syndrome With Predominant Myoclonic Seizures.

Journal of Child Neurology
Matthew MacdonaldAnita N Datta
July 27, 2021
Open Access

Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy.

Epilepsy & Behavior : E&B
Justin C StricklandRyan Vandrey
July 18, 2021

Efficacy and safety of rufinamide as adjunctive therapy in patients with Lennox Gastaut syndrome: A systematic review and Meta-analysis.

Seizure : the Journal of the British Epilepsy Association
Indar Kumar SharawatLesa Dawman
July 7, 2021

Clinical manifestation of CDKL5 deficiency disorder and identified mutations in a cohort of Slovak patients.

Epilepsy Research
Daniela KluckovaAndrej Ficek
July 4, 2021
Review

Epilepsy: Epileptic Syndromes and Treatment.

Neurologic Clinics
Akshat Katyayan, Gloria Diaz-Medina
July 3, 2021

Antiepileptogenic effects of rapamycin in a model of infantile spasms due to structural lesions.

Epilepsia
Ozlem AkmanAristea S Galanopoulou

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