Leptin in the Brain

Leptin is a pleiotropic hormone that impinges on many brain areas, and in doing so alters food intake, motivation, learning, memory, cognitive function, neuroprotection, reproduction, growth, metabolism, energy expenditure, and more. Here are the latest discoveries pertaining to leptin in the brain.

January 7, 2022

The Interactions between Adipose Tissue Secretions and Parkinson's disease; The Role of Leptin.

The European Journal of Neuroscience
Sara EkraminasabSina Rashedi
January 3, 2022
Preprint
Open Access

Integrated genomic analysis of AgRP neurons reveals that IRF3 regulates leptin's hunger-suppressing effects

BioRxiv : the Preprint Server for Biology
Frankie D HeywardE. D. Rosen
January 3, 2022
Open Access

Leptin Gene Protects Against Cold Stress in Antarctic Toothfish.

Frontiers in Physiology
Ying WangLiangbiao Chen
December 28, 2021

COVID-19 Outcome Relates With Circulating BDNF, According to Patient Adiposity and Age.

Frontiers in Nutrition
Luciele Guerra MinuzziFábio Santos Lira
December 22, 2021

Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity.

Nature Metabolism
Marta Porniece KumarJens C Brüning
December 16, 2021
Review

Hypothalamic inflammation in metabolic disorders and aging.

Cellular and Molecular Life Sciences : CMLS
Anup BhusalKyoungho Suk
December 14, 2021
Review

Early life nutrition and neuroendocrine programming.

Neuropharmacology
M H Vickers
December 14, 2021
Review

Visceral adiposity, inflammation, and hippocampal function in obesity.

Neuropharmacology
Alexis M Stranahan
December 11, 2021
Preprint
Open Access

Leptin-mediated suppression of food intake by conserved Glp1r-expressing neurons prevents obesity

BioRxiv : the Preprint Server for Biology
A. C. RuppMartin G. Myers
December 11, 2021
Review
Open Access

Leptin-A Potential Bridge between Fat Metabolism and the Brain's Vulnerability to Neuropsychiatric Disorders: A Systematic Review.

Journal of Clinical Medicine
Gilmara Gomes de Assis, Eugenia Murawska-Ciałowicz
November 20, 2021
Review
Open Access

Irx3 and Irx5 - Novel Regulatory Factors of Postnatal Hypothalamic Neurogenesis.

Frontiers in Neuroscience
Zhengchao DouChi-Chung Hui
November 20, 2021
Review
Open Access

Infection and Immunometabolism in the Central Nervous System: A Possible Mechanistic Link Between Metabolic Imbalance and Dementia.

Frontiers in Cellular Neuroscience
Noriko Shinjyo, Kiyoshi Kita
November 20, 2021
Review

AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity.

European Journal of Pharmacology
Muhammad Sufyan VohraWong Eng Hwa

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