Lewy Body Disease

Lewy Body Disease is associated with abnormal deposits of proteins like alpha-synuclein in the brain and causes a decline in mental abilities. Here is the latest research on this progressive neurological disorder.

January 11, 2021

Validation of FDG-PET datasets of normal controls for the extraction of SPM-based brain metabolism maps

European Journal of Nuclear Medicine and Molecular Imaging
Silvia Paola CaminitiClara Luigia Gobbo
December 29, 2020

Behavioral Deficits and Brain α-Synuclein and Phosphorylated Serine-129 α-Synuclein in Male and Female Mice Overexpressing Human α-Synuclein

Journal of Alzheimer's Disease : JAD
Lilit GabrielyanLixin Wang
January 3, 2021
Open Access

Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies

Journal of Molecular Cell Biology
Maarten C HardenbergMichele Vendruscolo
January 6, 2021
Open Access

Dementia risk in Parkinson's disease is associated with interhemispheric connectivity loss and determined by regional gene expression

NeuroImage. Clinical
Angeliki ZarkaliRimona S Weil
January 6, 2021
Open Access

Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study

Acta Neuropathologica
Johannes AttemsIan G McKeith
January 11, 2021
Preprint
Open Access

Impaired sensory evidence accumulation and network function in Lewy body dementia

MedRxiv : the Preprint Server for Health Sciences
Claire O'CallaghanJ.-P. Taylor
December 29, 2020
Open Access

11 C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates

European Journal of Nuclear Medicine and Molecular Imaging
Laura KueblerKristina Herfert
January 13, 2021
Review
Open Access

Imaging Familial and Sporadic Neurodegenerative Disorders Associated with Parkinsonism

Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics
David J Brooks
January 11, 2021
Open Access

Could COVID-19 anosmia and olfactory dysfunction trigger an increased risk of future dementia in patients with ApoE4?

Medical Hypotheses
Ciro ManzoAlberto Castagna
January 12, 2021
Open Access

Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo

Neurobiology of Disease
Antonio Dominguez-MeijideTiago Fleming Outeiro
January 1, 2021
Review
Open Access

Cognitive impact of COVID-19: looking beyond the short term

Alzheimer's Research & Therapy
Scott MinersSeth Love
December 22, 2020
Open Access

Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein

Neurobiology of Disease
Clare TweedyFiona E N LeBeau
January 11, 2021
Open Access

Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain

Neurobiology of Aging
Ryan K ShahidehpourAdam D Bachstetter
January 12, 2021
Open Access

The Cognitive Profile of Mild Cognitive Impairment Due to Dementia With Lewy Bodies-An Updated Review

Frontiers in Aging Neuroscience
Mathilde Suhr HemminghythMonica Haraldseid Breitve
January 6, 2021
Open Access

Tau PET and relative cerebral blood flow in dementia with Lewy bodies: A PET study

NeuroImage. Clinical
E E WoltersB N M van Berckel

Sign up to follow this feed and discover related papers.

Related Feeds

3D Cellular Models of Brain and Neurodegeneration

Brain organoids are three-dimensional in vitro cellular models of the brain that can recapitulate many processes such as the neurodevelopment. In addition, these organoids can be combined with other cell types, such as neurons and astrocytes to study their interactions in assembloids. Disease processes can also be modeled by induced pluripotent stem cell-derived organoids and assembloids from patients with neurodegenerative disorders. Discover the latest research on the models here.

ALS & FTD: TDP-43

TAR DNA-binding protein 43 (TDP-43) is a pathological protein identified in sporadic Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). Here are the latest discoveries pertaining to TDP-43 and these diseases.

ALS: Genetics

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ALS: Pathogenic Mechanisms

Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating pathogenic mechanisms that underlie this genetically heterogeneous disorder.

ALS: Phenotypes

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder characterized phenotypically by progressive muscle weakness. Clinical phenotypes of ALS can be classified based on the pattern, level, and area of onset (e.g. bulbar, cervical, lumbar). Here is the latest research investigating phenotypes of ALS.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here is the latest research on ALS and prions.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research in this field.

ALS: Therapies

Amyotrophic Lateral Sclerosis (ALS) is associated with the death of neurons that control voluntary muscles. This feed followes the latest research into therapies for this progressive neurodegenerative disease.

Age-related Dementia

Dementias are a group of conditions, including Alzheimer's disease, vascular dementia, and frontotemporal dementia, characterized by deficiencies in cognitive abilities. Age-related dementia refers to dementias that occur in older individuals, usually 60+ years old, in contrast to early-onset dementia. Follow the latest research on age-related dementia here.

Alexander Disease

Alexander disease is a rare leukodystrophy caused by mutations in the astrocyte-specific intermediate filament protein glial fibrillary acidic protein (GFAP). Here is the latest research on this disease.

© 2021 Meta ULC. All rights reserved
/feed-previews/lewy-body-disease/d845e2c9-fe0c-494f-a546-cfdd61fc59d7