The precise localization and structure of lymphoid organ development allows for an orchestrated immune response to an array of potential pathogens. Discover the latest research on Lymphoid Organ Development here.
Antibody engineering technologies are constantly advancing to improve the clinical effectiveness of monoclonal and bispecific antibodies. Discover the latest research on Antibody Engineering here.
Immunometabolism involves not only the way metabolites are digested by the immune system, but the way in which they can alter the pathway of the immune system. These responses occur in day-to-day healthy cell functioning, but can result in diseases, such as autoimmune disorders. Discover the latest research on cellular immunometabolism here.
Co-operation of immune cells in both innate and adaptive immunity is essential in mounting an appropriate immune effector cell response. Discover the latest research on Co-operation of Effector Responses here.
Cross-priming is the process whereby professional APC, mainly dendritic cells, prime t-cells by presenting antigens processed from proteins of other cells such as tumor cells or virus-infected cells. Discover the latest research on cross-priming here.
Follicular t helper cells are an important subset of helper t-cells which help to the formation of germinal centers and b-cells differentiation. Discover the latest research on follicular t helper cells here.
Immune complexes are formed by the binding of antibodies to soluble antigens eliciting an immune response and are prevalent in autoimmune diseases. Discover the latest research on Immune Complexes here.
Abnormal immune system maturation is influenced by microbial stimulation and is believed to be a driving force behind the increase in allergies among children. Discover the latest research on Immune Maturation here.
Immune microenvironments can influence cellular functions and signaling pathways, including those of tumor cells and their response to immunotherapies. Discover the latest research on Immune Microenvironments here.
Mapping the human immune system spatially, within and between tissues, will provide the basis for studying mechanisms of tissue residency and the effects of aging. This feed follos new studies profiling the immune system, including at different developmental stages.
Immunological surveillance occurs when T-cells detect and destroy virally infected or neoplastically transformed cells in the body. Discover the latest research on immunologic surveillance here.