Feed Preview

Lynch Syndrome

Lynch Syndrome diagram by Nephron [CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0)]
Nephron [CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0)]

Lynch Syndrome is a hereditary predisposition to development of certain cancers as a result of inherited mutations that impair DNA mismatch repair. Follow this feed to learn more.

Top 20 most recent papers
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

Nivolumab Is Effective in Mismatch Repair-Deficient Noncolorectal Cancers: Results From Arm Z1D-A Subprotocol of the NCI-MATCH (EAY131) Study

Journal of Clinical Oncology : Official Journal of the American Society of Clinical OncologyNovember 25, 2019
Nilofer Saba AzadKeith T Flaherty
37
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

Cancer Susceptibility Mutations in Patients With Urothelial Malignancies

Journal of Clinical Oncology : Official Journal of the American Society of Clinical OncologyDecember 3, 2019
Maria I CarloKenneth Offit
11
bioRxiv

Mutation analysis of multiple pilomatricomas in a patient with myotonic dystrophy type 1 suggests a DM1-associated hypermutation phenotype

bioRxivNovember 15, 2019
Albert RübbenClaudio Cacchi
5
Gut

Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)/Association of Coloproctology of Great Britain and Ireland (ACPGBI)/United Kingdom Cancer Genetics Group (UKCGG)

GutNovember 28, 2019
Kevin John MonahanHereditary CRC guidelines eDelphi consensus group
65
1
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc

NTRK gene rearrangements are highly enriched in MLH1/PMS2 deficient, BRAF wild-type colorectal carcinomas-a study of 4569 cases

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, IncDecember 2, 2019
Angela ChouAnthony J Gill
bioRxiv

High-efficiency multi-site genomic editing (HEMSE) of Pseudomonas putida through thermoinducible ssDNA recombineering

bioRxivNovember 21, 2019
Tomas AparicioVíctor de Lorenzo
20
Personalized Medicine

Implementing universal cancer screening programs can help sustain genomic medicine programs

Personalized MedicineDecember 4, 2019
Alanna Kulchak RahmBrandie Heald
Gynecologic Oncology

Low rates of cascade genetic testing among families with hereditary gynecologic cancer: An opportunity to improve cancer prevention

Gynecologic OncologyNovember 25, 2019
Natalie E GriffinAndrea R Hagemann
14
Gastroenterology

Use of Family History and Genetic Testing to Determine Risk of Colorectal Cancer

GastroenterologyNovember 21, 2019
Fay KastrinosRandall W Burt
8
Public Health Genomics

The Current Practice of Lynch Syndrome Diagnosis and Management in Italy: A Qualitative Assessment

Public Health GenomicsDecember 5, 2019
Alessia TognettoStefania Boccia
Journal of Vascular Surgery Cases and Innovative Techniques

En bloc resection of visceral aorta and right kidney due to aortic sarcoma using temporary extracorporeal bypass grafting

Journal of Vascular Surgery Cases and Innovative TechniquesDecember 1, 2019
Patrick BjörkmanAnders N Albäck
Journal of Clinical Pathology

Histological and molecular diversity and heterogeneity of precancerous lesions associated with inflammatory bowel diseases

Journal of Clinical PathologyDecember 4, 2019
Xian-Yong GuiDouglas James Demetrick
Zeitschrift für Gastroenterologie

Current recommendations for surveillance, risk reduction and therapy in Lynch syndrome patients

Zeitschrift für GastroenterologieNovember 1, 2019
Robert HüneburgJacob Nattermann
1
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Identification of hypermutation and defective mismatch repair in ctDNA from metastatic prostate cancer

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchNovember 19, 2019
Elie J RitchAlexander William Wyatt
17
World Journal of Gastrointestinal Oncology

Clinical significance of MLH1 /MSH2 for stage II/III sporadic colorectal cancer

World Journal of Gastrointestinal OncologyNovember 15, 2019
Shui-Ming WangY L Wang
Virchows Archiv : an International Journal of Pathology

PD-L1 expression in gastroesophageal dysplastic lesions

Virchows Archiv : an International Journal of PathologyNovember 14, 2019
Matteo FassanFotios Loupakis
Current Treatment Options in Gastroenterology

Incorporating Colorectal Cancer Genetic Risk Assessment into Gastroenterology Practice

Current Treatment Options in GastroenterologyNovember 18, 2019
Benjamin SternMaria Wagner Baker
10
Gynecologic Oncology

Clinical outcomes of patients with POLE mutated endometrioid endometrial cancer

Gynecologic OncologyNovember 19, 2019
Marina StasenkoKaren A Cadoo
2
Journal of Medical Genetics

Retesting of women who are negative for a BRCA1 and BRCA2 mutation using a 20-gene panel

Journal of Medical GeneticsNovember 29, 2019
Jordan Lerner-EllisGeorge S Charames
Clinical Epigenetics

Highly sensitive MLH1 methylation analysis in blood identifies a cancer patient with low-level mosaic MLH1 epimutation

Clinical EpigeneticsNovember 28, 2019
Estela DámasoMarta Pineda

See more papers from this feed

Related Feeds

Anal Dysplasia

Anal dysplasia is a precancerous condition in which some cells within the anus transform into abnormal cells. Discover the latest research on anal dysplasia here.

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.

Barrett Esophagus

Barrett’s esophagus if a serious complication of gastroesophageal reflux disease during which the normal esophageal lining changes to tissue that resembles intestinal lining. Here is the latest research.

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.

Bowen's Disease

Bowen's disease is thought of as an easily-treatable early stage of skin cancer, characterized by red, scaly patches on the skin. Discover the latest research on Bowen's disease here.

Cervical Dysplasia

Cervical dysplasia also known as Cervical intraepithelial neoplasia, refers to abnormal cell growth on the surface of the cervix that may be precancerous. Follow this feed to keep updated on this topic.

Keratosis, Actinic

Actinic Keratosis are lesions causes by sun-induced DNA damage to keratinocytes in exposed skin areas. These lesions are considered precancerous and, if left untreated, can result in superficial squamous cell carcinoma. Here is the latest research.

Lichen Sclerosus

Lichen planus is the inflammation of the mucous membranes of the mouth. Discover the latest research on lichen planus here.

Preleukemia

Preleukemia refers to a hemic and lymphatic disease in which the bone marrow does not produce enough blood cells. Here is the latest research.

Uterine Cervical Dysplasia

Cervical dysplasia, also known as vertical intraepithelial neoplasia, is a precancerous condition characterized by abnormal cell growth on the surface lining of the cervix. Here is the latest research.

© 2019 Meta ULC. All rights reserved
/feed-previews/lynch-syndrome/5e7b4a2e-ef42-47a1-b144-26cb31e42641