Lynch Syndrome

Lynch Syndrome is a hereditary predisposition to development of certain cancers as a result of inherited mutations that impair DNA mismatch repair. Follow this feed to learn more.

October 27, 2020

LAG-3 expression associates with poor prognosis and immunoevasive contexture in EBV-positive and MLH1-defective gastric cancer patients

International Journal of Cancer. Journal International Du Cancer
Kunpeng LvJiejie Xu
October 12, 2020

Ensemble learning models that predict surface protein abundance from single-cell multimodal omics data

Methods : a Companion to Methods in Enzymology
Fan XuJie Zheng
October 16, 2020
Open Access

Topoisomerase IB interacts with genome segregation proteins and is involved in multipartite genome maintenance in Deinococcus radiodurans

Microbiological Research
Swathi KotaHari S Misra
October 13, 2020
Open Access

In vivo vaccination with cell line-derived whole tumor lysates – neoantigen quality, not quantity matters

Inken SalewskiClaudia Maletzki
October 13, 2020

ATAC-seq Reveals an Isl1 Enhancer that Regulates Sinoatrial Node Development and Function

Circulation Research
Giselle GalangVasanth Vedantham
October 13, 2020

Human Pacemaker Regulatory Element Analysis Identifies TBX3 Pacemaker Enhancer

Circulation Research
Vincent Ww van EifVincent M Christoffels
October 23, 2020
Open Access

DNA mismatch repair-dependent DNA damage responses and cancer

DNA Repair
Robbert IjsselsteijnNiels de Wind
October 19, 2020
Open Access

Variant-to-gene-mapping analyses reveal a role for the hypothalamus in genetic susceptibility to inflammatory bowel disease

Cellular and Molecular Gastroenterology and Hepatology
Chiara LasconiStruan F A Grant
October 9, 2020
Open Access

Unbiased identification of nanoparticle cell uptake mechanism via a genome-wide CRISPR/Cas9 knockout screen

BioRxiv : the Preprint Server for Biology
E. L. Van NostrandGene W Yeo
October 19, 2020

QTL-seq analysis of powdery mildew resistance in a Korean cucumber inbred line

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
Chunying ZhangSanghyeob Lee
October 22, 2020

Tumor site discordance in mismatch repair deficiency in synchronous endometrial and ovarian cancers

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Soyoun Rachel KimSarah Elizabeth Ferguson
October 14, 2020

Role of Tumor Mutation Burden Analysis in Detecting Lynch Syndrome in Precision Medicine: Analysis of 2,501 Japanese Cancer Patients

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Yoshimi KiyozumiKen Yamaguchi
October 16, 2020
Open Access

High-Resolution Genome-Wide Occupancy in Candida spp. Using ChEC-seq

Faiza TebbjiAdnane Sellam

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