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Lynch Syndrome

Lynch Syndrome diagram by Nephron, Wikimedia
Nephron, Wikimedia

Lynch Syndrome is a hereditary predisposition to development of certain cancers as a result of inherited mutations that impair DNA mismatch repair. Follow this feed to learn more.

Top 20 most recent papers
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc

Clinicopathological significance of deficient DNA mismatch repair and MLH1 promoter methylation in endometrioid endometrial carcinoma

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, IncFebruary 16, 2020
Annukka PasanenRalf Bützow
5
Cell & Bioscience

DNA mismatch repair in the context of chromatin

Cell & BioscienceFebruary 7, 2020
Yaping Huang, Guo-Min Li
International Journal of Cancer. Journal International Du Cancer

Distinct clinical phenotype and genetic testing strategy for Lynch syndrome in China based on a large colorectal cancer cohort

International Journal of Cancer. Journal International Du CancerFebruary 8, 2020
Lin DongShuangmei Zou
Cancer Prevention Research

A Multi-Institutional Cohort of Therapy-Associated Polyposis in Childhood and Young Adulthood Cancer Survivors

Cancer Prevention ResearchFebruary 14, 2020
Leah H BillerMatthew B Yurgelun
13
4
Journal of Cancer Research and Clinical Oncology

A novel DNA damage response signature of IDH-mutant grade II and grade III astrocytoma at transcriptional level

Journal of Cancer Research and Clinical OncologyFebruary 16, 2020
Qi LiuPei Yang
1
Familial Cancer

Mismatch repair gene pathogenic germline variants in a population-based cohort of breast cancer

Familial CancerFebruary 16, 2020
Tu Nguyen-DumontMelissa C Southey
1
OncoTargets and Therapy

Optimal Management of Upper Tract Urothelial Carcinoma: Current Perspectives

OncoTargets and TherapyFebruary 6, 2020
Jeffrey J LeowYew-Lam Chong
3
1
Acta Neuropathologica Communications

The efficacy of DNA mismatch repair enzyme immunohistochemistry as a screening test for hypermutated gliomas

Acta Neuropathologica CommunicationsFebruary 14, 2020
Matthew McCordCraig Horbinski
5

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