Lynch Syndrome

Lynch Syndrome is a hereditary predisposition to development of certain cancers as a result of inherited mutations that impair DNA mismatch repair. Follow this feed to learn more.

July 6, 2020

Next-generation sequencing reveals heterogeneous genetic alterations in key signaling pathways of mismatch repair deficient colorectal carcinomas

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc
Jing WangZhiyong Liang
July 9, 2020
Open Access

NAIGO: An Improved Method to Align PPI Networks Based on Gene Ontology and Graphlets

Frontiers in Bioengineering and Biotechnology
Lijuan ZhuJialiang Yang
June 26, 2020
Review
Open Access

Evolving pathologic concepts of serrated lesions of the colorectum

Journal of Pathology and Translational Medicine
Jung Ho Kim, Gyeong Hoon Kang
June 28, 2020

Clinicopathologic features and prognosis of synchronous and metachronous multiple primary colorectal cancer

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
C ZhangX Su
June 28, 2020

Genomic characterization of vulvar squamous cell carcinoma

Gynecologic Oncology
Katharina PrieskeLinn Woelber
July 10, 2020

Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa

Gut
Laura Reyes-UribeEduardo Vilar
July 2, 2020

Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals

Genetics in Medicine : Official Journal of the American College of Medical Genetics
Paul LacazeEric Schadt
June 21, 2020

PARP inhibition suppresses the emergence of temozolomide resistance in a model system

Journal of Neuro-oncology
Alice L YuanMichael D Blough
July 9, 2020

HPV nonrelated endocervical adenocarcinoma in hereditary cancer syndromes

Tumori
Ileana CarnevaliMaria Grazia Tibiletti
July 8, 2020
Open Access

Neoadjuvant Immunotherapy-Based Systemic Treatment in MMR-Deficient or MSI-High Rectal Cancer: Case Series

Journal of the National Comprehensive Cancer Network : JNCCN
Rahel DemisseMay Cho
June 23, 2020
Open Access

Comprehensive characterization of driver genes in diffuse large B cell lymphoma

Oncology Letters
Zheng FanYing Lu
July 10, 2020

Genetic characteristics of gastric-type mucinous carcinoma of the uterine cervix

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc
Eunhyang ParkNam Hoon Cho
July 9, 2020
Open Access

Comprehensive Constitutional Genetic and Epigenetic Characterization of Lynch-Like Individuals

Cancers
Estela DámasoGabriel Capellá
June 23, 2020
Open Access

A First Step to a Biomarker of Curative Surgery in Colorectal Cancer by Liquid Biopsy of Methylated Septin 9 Gene

Disease Markers
M Leon ArellanoD García-Olmo

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